Late Stage Fluorination Of Bioactive Molecules And Biologically Relevant Substrates
DOWNLOAD
FREE 30 Days
Download Late Stage Fluorination Of Bioactive Molecules And Biologically Relevant Substrates PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Late Stage Fluorination Of Bioactive Molecules And Biologically Relevant Substrates book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Late Stage Fluorination Of Bioactive Molecules And Biologically Relevant Substrates
DOWNLOAD
FREE 30 Days
Author : Al Postigo
language : en
Publisher: Elsevier
Release Date : 2018-09-05
Late Stage Fluorination Of Bioactive Molecules And Biologically Relevant Substrates written by Al Postigo and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-05 with Science categories.
Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work. Highlights the latest developments in the field in a concise volume Provides details of key fluorinating reagents across diverse families of organic compounds Explores the current applications and future potential of fluorine in drug development
Nontraditional Activation Methods In Green And Sustainable Applications
DOWNLOAD
FREE 30 Days
Author : Bela Torok
language : en
Publisher: Elsevier
Release Date : 2021-02-25
Nontraditional Activation Methods In Green And Sustainable Applications written by Bela Torok and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-25 with Science categories.
Nontraditional Activation Methods in Green and Sustainable Applications: Microwaves; Ultrasounds; Photo-, Electro- and Mechan-ochemistry and High Hydrostatic Pressure provides a broad overview of non-traditional activation methods to help readers identify and use appropriate approaches in reducing the environmental impact of their work. Sections discuss the fundamental principles of each method and provide examples of their practical use, illustrating their usefulness. Given the importance of expanding laboratory based technologies to the industrial level, chapters that cover both existing and potential industrial and environmental applications are also included. Highlighting the usefulness and adaptability of these methods for a range of practical applications, this book is a practical guide for both those involved with the design and application of synthetic methodologies and those interested in the implementation and impact of green chemistry principles in practice, from synthetic and medicinal chemists, to food developers and environmental policy planners. Discusses, and critically assesses, the advantages of non-traditional activation methods in green and sustainable chemistry applications Features individual chapters written by renowned experts in the field Contains extensive, state-of-the-art reference sections, providing critically filtered information to readers
Principles Of Molecular Probe Design And Applications
DOWNLOAD
FREE 30 Days
Author : Wellington Pham
language : en
Publisher: Springer Nature
Release Date : 2022-09-26
Principles Of Molecular Probe Design And Applications written by Wellington Pham and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-26 with Technology & Engineering categories.
This book describes insight mechanisms for designing molecular probes and methods that these agents can be used for medical diagnosis in preclinical animal models via optical, MRI and PET imaging. The book has a wealth of schemes of synthesis and methods deduced from pioneers in the field, making it possible to immerse into real-world molecular imaging. Written for graduate student training and practitioners, this book will serve as a teaching material and/or reference for anyone interested in exploring the power of chemical synthesis of imaging agents.
Organofluorine Chemistry
DOWNLOAD
FREE 30 Days
Author : Kalman J. Szabo
language : en
Publisher: John Wiley & Sons
Release Date : 2021-01-05
Organofluorine Chemistry written by Kalman J. Szabo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-05 with Science categories.
By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!
Fluorine And Health
DOWNLOAD
FREE 30 Days
Author : Alain Tressaud
language : en
Publisher: Elsevier
Release Date : 2008-06-06
Fluorine And Health written by Alain Tressaud and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-06 with Medical categories.
Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. New approach of topics involving chemistry, biology and medicinal techniques Transdisciplinar papers on fluoride products Importance of fluoride products in health Updated data on specific topics
Fluorination
DOWNLOAD
FREE 30 Days
Author : Jinbo Hu
language : en
Publisher: Springer
Release Date : 2020-08-12
Fluorination written by Jinbo Hu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-12 with Science categories.
This volume reviews the recent advances in formation of C-F bonds and X-F bonds (X = heteroatom) to produce useful fluorinated molecules for pharmaceuticals, materials and more. Reactions and methods associated with fluorination, including monofluorination, difluorination, trifluorination and other polyfluorination that have emerged within the past few years are systematically discussed. With contributions from front-line researchers in this field from both academia and industry, this book provides a valuable resource for scholars, graduate students as well as professionals.
Advances In Organic Synthesis
DOWNLOAD
FREE 30 Days
Author : Atta-ur-Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2011-01-10
Advances In Organic Synthesis written by Atta-ur-Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-10 with Science categories.
"The volume focuses on recent advances in organofluorine chemistry directed towards selective fluorine introduction into various target molecules, employing both traditional and contemporary, electrophilic and nucleophilic, fluorinating agents. It brings t"
Modern Synthesis Processes And Reactivity Of Fluorinated Compounds
DOWNLOAD
FREE 30 Days
Author : Henri Groult
language : en
Publisher: Elsevier
Release Date : 2016-11-04
Modern Synthesis Processes And Reactivity Of Fluorinated Compounds written by Henri Groult and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-04 with Science categories.
Modern Synthesis Processes and Reactivity of Fluorinated Compounds focuses on the exceptional character of fluorine and fluorinated compounds. This comprehensive work explores examples taken from all classes of fluorine chemistry and illustrates the extreme reactivity of fluorinating media and the peculiar synthesis routes to fluorinated materials. The book provides advanced and updated information on the latest synthesis routes to fluorocompounds and the involved reaction mechanisms. Special attention is given to the unique reactivity of fluorine and fluorinated media, along with the correlation of those properties to valuable applications of fluorinated compounds. Contains quality content edited, and contributed, by leading scholars in the field Presents applied guidance on the preparation of original fluorinated compounds, potentially transferable from the lab scale to industrial applications Provides practical synthesis information for a wide audience interested in fluorine compounds in many branches of chemistry, materials science, and physics
Photocatalysis
DOWNLOAD
FREE 30 Days
Author : Dionysios D Dionysiou
language : en
Publisher: Royal Society of Chemistry
Release Date : 2016-03-30
Photocatalysis written by Dionysios D Dionysiou and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-30 with Science categories.
From environmental remediation to alternative fuels, this book explores the numerous important applications of photocatalysis. The book covers topics such as the photocatalytic processes in the treatment of water and air; the fundamentals of solar photocatalysis; the challenges involved in developing self-cleaning photocatalytic materials; photocatalytic hydrogen generation; photocatalysts in the synthesis of chemicals; and photocatalysis in food packaging and biomedical and medical applications. The book also critically discusses concepts for the future of photocatalysis, providing a fascinating insight for researchers. Together with Photocatalysis: Fundamentals and Perspectives, these volumes provide a complete overview to photocatalysis.
Arene Chemistry
DOWNLOAD
FREE 30 Days
Author : Jacques Mortier
language : en
Publisher: John Wiley & Sons
Release Date : 2015-11-30
Arene Chemistry written by Jacques Mortier and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-30 with Science categories.
Organized to enable students and synthetic chemists to understand and expand on aromatic reactions covered in foundation courses, the book offers a thorough and accessible mechanistic explanation of aromatic reactions involving arene compounds. • Surveys methods used for preparing arene compounds and their transformations • Connects reactivity and methodology with mechanism • Helps readers apply aromatic reactions in a practical context by designing syntheses • Provides essential information about techniques used to determine reaction mechanisms