Leukemia Stem Cells In Hematologic Malignancies
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Leukemia Stem Cells In Hematologic Malignancies
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Author : Haojian Zhang
language : en
Publisher: Springer
Release Date : 2019-07-23
Leukemia Stem Cells In Hematologic Malignancies written by Haojian Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with Medical categories.
This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function. With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs. Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research etc.
Molecular Aspects Of Hematologic Malignancies
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Author : Michal Witt
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-30
Molecular Aspects Of Hematologic Malignancies written by Michal Witt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-30 with Science categories.
This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Leukemia Stem Cells
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Author : César Cobaleda
language : en
Publisher:
Release Date : 2021
Leukemia Stem Cells written by César Cobaleda and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Leukemia categories.
Childhood Cancer And Functional Impacts Across The Care Continuum
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Author : National Academies of Sciences Engineering and Medicine
language : en
Publisher:
Release Date : 2021-09-09
Childhood Cancer And Functional Impacts Across The Care Continuum written by National Academies of Sciences Engineering and Medicine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-09 with categories.
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Allogeneic Stem Cell Transplantation
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Author : Hillard M. Lazarus
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-02
Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-02 with Medical categories.
Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Hematologic Malignancies Acute Leukemias
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Author : S.H. Faderl
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-21
Hematologic Malignancies Acute Leukemias written by S.H. Faderl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-21 with Medical categories.
Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. This hugely important new book describes the current knowledge of acute leukemia biology and discusses new classification systems that have arisen as a result of emerging insights into pathogenesis. Estey, Faderl and Kantarjian, who all work at the respected Anderson Cancer Center in Houston, Texas, USA, examine in detail advances in the treatment of particular types of acute leukemia. Their book also covers the management of acute leukemia in general as well as the development of new therapies. This book will be extremely useful to clinicians.
Stem Cell Transplantation For Hematologic Malignancies
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Author : Robert J. Soiffer
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-01-29
Stem Cell Transplantation For Hematologic Malignancies written by Robert J. Soiffer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-29 with Medical categories.
A comprehensive survey of the current state-of-the-art in hematopoietic stem cell transplantation for malignant disease. The authors focus on the indications and results of transplantation for acute leukemia, chronic myelogenous leukemia, lymphoma, multiple myeloma, and breast cancer. Special attention is given to transplant-related complications, including the pathophysiology and clinical consequences of acute and chronic GVHD, delayed immune reconstitution leading to infectious complications, and organ damage to the lung and liver. Additional chapters address the sources of stem cells and the effects of graft manipulation used to eliminate residual contaminating tumor cells in autologous transplantation, or to reduce the number of T lymphocytes causing GVHD in allogenic transplantation.
Hematologic Malignancies
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Author : Michael B. Tomblyn
language : en
Publisher: Demos Medical Publishing
Release Date : 2012
Hematologic Malignancies written by Michael B. Tomblyn and has been published by Demos Medical Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Blood categories.
Authoritative reviews and updates discuss recent advances in radiation therapy in treatment of Hodgkins lymphoma, B-cell nodal and extranodal lymphomas, follicular lymphoma and cutaneous T-cell lymphoma; mantle cell lymphoma, and leukemia. In addition, reviews of current developments in PET imaging in lymphoma, radioimmunotherapy, and radiation and transplant, are included. This volume of Radiation Medicine Rounds gives the radiation oncology professional a complete overview of current best practice and emerging modalities for radiation treatment of hematologic malignancies.Hematologic Maligna.
Targeting The Microenvironment Niche In Hematologic Malignancies
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Author : Cirino Botta
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-02
Targeting The Microenvironment Niche In Hematologic Malignancies written by Cirino Botta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-02 with Medical categories.
Advances In Hematopoietic Stem Cell Research
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Author : Rosana Pelayo
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-01-27
Advances In Hematopoietic Stem Cell Research written by Rosana Pelayo and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-27 with Science categories.
This book provides a comprehensive overview in our understanding of the biology and therapeutic potential of hematopoietic stem cells, and is aimed at those engaged in stem cell research: undergraduate and postgraduate science students, investigators and clinicians. Starting from fundamental principles in hematopoiesis, Advances in Hematopoietic Stem Cell Research assemble a wealth of information relevant to central mechanisms that may regulate differentiation, and expansion of hematopoietic stem cells in normal conditions and during disease.