Lipid And Protein Regulation Of Membrane Trafficking
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Lipid And Protein Regulation Of Membrane Trafficking
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Author : Junyong Jia
language : en
Publisher:
Release Date : 2007
Lipid And Protein Regulation Of Membrane Trafficking written by Junyong Jia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Protein Lipid And Membrane Traffic
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Author : North Atlantic Treaty Organization. Scientific Affairs Division
language : en
Publisher: IOS Press
Release Date : 2000
Protein Lipid And Membrane Traffic written by North Atlantic Treaty Organization. Scientific Affairs Division and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Biological transport categories.
This text concentrates on the following specific topics: the dynamic character of lipids and proteins in biological membranes; the existence of specific domains in membranes including their visualisation; the molecular mechanisms of intracellular transport of membrane constituents and the involvement of lipid-protein interactions in these processes; protein assembly; structure and folding and transport through membranes; and the intracellular sorting and targeting of individual membrane components as well as different organelles."
Regulation Of Lipid Metabolism And Membrane Trafficking By The Oxysterol Binding Protein Superfamily Member Kes1
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Author : Marissa LeBlanc
language : en
Publisher:
Release Date : 2010
Regulation Of Lipid Metabolism And Membrane Trafficking By The Oxysterol Binding Protein Superfamily Member Kes1 written by Marissa LeBlanc and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Connections To Membrane Trafficking Where You Least Expect Them Diseases Dynamics Diet And Distance
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Author : Rachel Susan Kraut
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-28
Connections To Membrane Trafficking Where You Least Expect Them Diseases Dynamics Diet And Distance written by Rachel Susan Kraut and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-28 with categories.
Membrane Trafficking
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Author : Ales Vancura
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-28
Membrane Trafficking written by Ales Vancura and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-28 with Science categories.
As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes.
Regulatory Mechanisms Of Intracellular Membrane Transport
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Author : Sirkka Keränen
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-08-27
Regulatory Mechanisms Of Intracellular Membrane Transport written by Sirkka Keränen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-08-27 with Medical categories.
This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many essential molecules involved in intracellular membrane/protein transport are emerging. A huge task now is to compile the molecular networks that govern these processes. Understanding of regulatory processes and participating molecules are likely to reveal global cellular regulatory circuits that couple membrane trafficking with other cellular functions. Such cell biological features are only starting to emerge. This book puts special emphasis on such mechanisms and processes. The contents discusses the role of coat proteins, tethering complexes, small rab GTPases, Sec1-family proteins and SNARE molecule phosphorylation in exocytosis, endocytosis and membrane fusion. In addition, the role of lipids in vesicle formation and membrane fusion, and some specialized cell biological denovo membrane generation processes are discussed.
Molecular Organization Of Membranes Where Biology Meets Biophysics
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Author : Marek Cebecauer
language : en
Publisher: Frontiers Media SA
Release Date : 2018-02-07
Molecular Organization Of Membranes Where Biology Meets Biophysics written by Marek Cebecauer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-07 with categories.
Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, regulate the function of all associated molecules. Therefore, studying interactions of components, biophysical properties and overall membrane dynamics provides essential information on its function in the context of cell activities. Such knowledge can contribute to biomedical fields such as pharmacology, immunology, neurobiology and many others. The goal of the Research Topic entitled ‘Molecular organisation of membranes: where biology meets biophysics’ was to provide a comprehensive platform for publishing articles, reviews and opinions focused on membrane organisation and the forces behind its heterogeneous and dynamic structure. We collected 11 works which cover topics as diverse as general membrane organisation models, membrane trafficking and signalling regulation, biogenesis of caveolae, protein-lipid interactions and the importance of membrane-associated tetraspanins networks. The prevalent theme was the existence of membrane nanodomains. To this point, new emerging technologies are presented which own the power to bring a novel insight on how membrane nanodomains are formed and maintained and what is their function. We believe that the collection of works in this Research Topic brings forward some important questions which will stimulate further research in this difficult but exciting field.
Nonvesicular Transport
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Author : Stephen S. Rothman
language : en
Publisher: Wiley-Interscience
Release Date : 1985
Nonvesicular Transport written by Stephen S. Rothman and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Science categories.
This book presents a range of articles on varied topics that consider evidence for the existence of nonvesicular transport for processes that have generally been considered to be carried out by means of vesicle mechanisms, particularly for the movement of proteins and neurotransmitters across membranes. The contributors base their hypotheses on knowledge of the kinetic, thermodynamic, and compartmental characteristics of a process in real space-time, independent of specific models that attempt to explain it.
Two Studies In Membrane Trafficking
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Author : Holly Christine Dippold
language : en
Publisher:
Release Date : 2009
Two Studies In Membrane Trafficking written by Holly Christine Dippold and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Eukaryotic cells maintain a complex organization of vesicular transport pathways through which integral membrane proteins and lipids travel. This allows the cell to maintain the proper functional composition of various intracellular membrane-bound compartments and communication with the external environment via the plasma membrane. I have studied two facets of vesicular trafficking. Chapter 1 describes the process of vesicle budding from the Golgi and its relationship to the unique morphology of the Golgi. Chapter 2 discusses the regulation of endocytosis and an attempt to find a target for a ubiquitin-specific protease necessary for endocytosis in yeast. The mechanism underlying the Golgi's flattened structure and its relation to secretory function is an intriguing question in cell biology. Golgi membranes, from yeast to humans, are enriched in phosphatidylinositol-4-phosphate (PtdIns(4)P). In a lipid binding screen, GOLPH3 was identified as a novel PtdIns(4)P-binding protein that depends upon PtdIns(4)P for its Golgi localization. GOLPH3 binds MYO18A, connecting the Golgi to F-actin, thus transmitting a tensile force necessary for Golgi budding and morphology. The same process generating the extended Golgi ribbon observed by fluorescence microscopy and the flattened form observed by electron microscopy drives the formation of transport vesicles. Integral plasma membrane proteins are down-regulated by endocytosis followed by trafficking to the lysosome for degradation. Can1p is a yeast arginine permease at the plasma membrane and undergoes such regulation. Canavanine is a toxic arginine analog that enters the cell through Can1p. A screen of viable yeast deletion mutants to identify genes which when deleted result in hypersensitivity to canavanine was conducted to identify novel components involved in down-regulation and internalization of plasma membrane proteins. Three genes identified were ubiquitin-specific proteases. By visual screening, deletion of UBP3 (UBiquitin-specific Protease 3) was observed to stabilize Can1p-GFP and other endocytic cargoes at the plasma membrane. Rescue experiments show that Ubp3p catalytic activity is necessary for endocytosis. Biochemical experiments indicate that Ubp3p is in a complex with Bre5p, and that Bre5p is also necessary for plasma membrane protein internalization. In conclusion, Ubp3p and its co-factor Bre5p are responsible for deubiquitination and positive regulation of an unidentified protein involved in endocytosis.
Intracellular Cholesterol Trafficking
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Author : Ta-Yuan Chang
language : en
Publisher: Springer Science & Business Media
Release Date : 1998
Intracellular Cholesterol Trafficking written by Ta-Yuan Chang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
The current understanding of cholesterol transport has moved from a largely descriptive science into the molecular stage. Intracellular Cholesterol Trafficking reports on the current state of research and features sections on: The Regulation of ACAT and Intracellular Cholesterol Level Niemann-Pick Type C Disease Cholesterol Transport in Specialized Cells Sterol Carrier Protein-2 and Cholesterol Transport Proteins Caveolae and Caveolin Summary and Future Perspectives . Intracellular Cholesterol Trafficking is sure to appeal to cell biologists, biochemists, endocrinologists, hepatologists, and atherosclerosis researchers.