Lipid Mediated Protein Signaling


Lipid Mediated Protein Signaling
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Lipid Mediated Protein Signaling


Lipid Mediated Protein Signaling
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Author : Daniel G.S. Capelluto
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-17

Lipid Mediated Protein Signaling written by Daniel G.S. Capelluto and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-17 with Medical categories.


This book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells. Also, there are some chapters that go beyond and expand these studies of protein-lipid interactions at the structural level. The book begins with a literature review from investigations associated to sphingolipids, followed by studies that describe the role of phosphoinositides in signaling and closing with the function of other key lipids in signaling at the plasma membrane and intracellular organelles.



Lipid Mediated Signaling


Lipid Mediated Signaling
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Author : Eric J. Murphy
language : en
Publisher: CRC Press
Release Date : 2010-03-05

Lipid Mediated Signaling written by Eric J. Murphy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-05 with Medical categories.


As the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade's worth of advances in research techniques that are pertinent in understand



Inositol Lipids In Cell Signalling


Inositol Lipids In Cell Signalling
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Author : R. H. Michell
language : en
Publisher:
Release Date : 1989

Inositol Lipids In Cell Signalling written by R. H. Michell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Science categories.


The discovery that inositol lipids are integral in cellular signaling mechanisms has been one of the most exciting breakthroughs in recent years. As secondary messengers in a wide variety of tissues and involved processes as diverse as rapid contraction of skeletal muscle, insulin secretion, and the slow activation of cell proliferation in cancer cells, their impact on biochemistry is akin to that of cyclic AMP two decades ago. Drawing together the many strands of research on inositol lipid-mediated signalling and containing contributions by leading authorities in their fields, Inositol Lipids in Cell Signalling is essential for any involved biochemist, cell biologist, or pharmacologist.



New Developments In Lipid Protein Interactions And Receptor Function


New Developments In Lipid Protein Interactions And Receptor Function
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Author : K.W.A. Wirtz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

New Developments In Lipid Protein Interactions And Receptor Function written by K.W.A. Wirtz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


A NATO Advanced Study Institute on "New Developments in Lipid-Protein Interactions and Receptor Function" was held on the Island of Spetsai, Greece, from August 16-27, 1992. This Institute was organized to bring together researchers in the field of membrane organization and dynamics with those actively involved in studies on receptor function, signal transduction mechanisms and gene regulation. 2 Presentations and discussions focussed on the regulation of intracellular Ca +-levels, on the second messengers derived from inositol lipids and on the specific phospholipase C isozymes involved in these processes. A major focus was on G-proteins and the effect of lipid anchors on their function. These principles of regulation were further discussed in the context of receptors for acetylcholine, lysophosphatidic acid and low-density lipoproteins. In addition, various aspects of the genomic regulation of cell growth and differentiation by transcription factors were presented. These topics were put into perspective by discussing the most recent developments in lipid-protein interactions, protein insertion into membranes, membrane lipid organization and lipid dynamics as mediated by phospholipid transfer proteins. This book presents the content of the major lectures and a selection of the most relevant of the most important topics posters. These proceedings offer a comprehensive account presented during the course of the Institute. The book is intended to make these proceedings accessible to a large audience.



Lipid Second Messengers


Lipid Second Messengers
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Author : Robert M. Bell
language : en
Publisher: Springer Science & Business Media
Release Date : 1996-05-31

Lipid Second Messengers written by Robert M. Bell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-05-31 with Medical categories.


Scientists in lipid biochemistry research have increasingly recognized the role of lipids as signaling molecules, aside from their importance in forming cellular membranes and storing energy. This book provides the latest findings on a wide variety of complex lipids in cells that function either as intracellular or intercellular messengers. International investigators present current data on the most extensively studied examples of both intracellular and intercellular messengers generated from lipids, and describe their basic mechanisms, which also utilize receptors in the G-protein-coupled family. The in-depth discussions address such topics as lipid signaling for protein kinase C activation, phosphatidic acid and lyso-phosphatidic acid, ceramide as a messenger, bioactive properties of Sphingosine and structurally related compounds, platelet-activating factor and PAF-like mimetics, and prostaglandins and related compounds. Lipid Second Messengers is an up-to-date reference on developments in the expanding field of lipid-derived signals and will be of interest to biochemists, physiologists, pharmacologists, geneticists, and biologists.



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.




Phospholipid Metabolism In Cellular Signaling


Phospholipid Metabolism In Cellular Signaling
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Author : Jose M. Mato
language : en
Publisher: CRC Press
Release Date : 2018-01-18

Phospholipid Metabolism In Cellular Signaling written by Jose M. Mato and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.


Phospholipids are no longer considered exclusively as the building blocks of biomembranes, but are now regarded to be exceptionally important to cellular signalling.Another conclusion resulting from studies over the past several years is that no single general scheme for the role of phospholipids during cell activation can be drawn as representative of all cells. This book presents a comprehensive view of the recent advances made in certain major research areas within the field of phospholipid metabolism in cellular signalling. Topics discussed within this volume include lipid composition of cellular membranes and their organization in biological systems, the dynamic aspects of phospholipid metabolism and its regulation by extracellular stimuli, and the role of newly discovered glycosyl-phosphatidylinositols in insulin action . The book also discusses two biologically active phospholipids: the sphingolipids, and ether-linked glycerophospholipids (the platelet activating factor). Phospholipid Metabolism in Cellular Signaling is an important research reference that should be considered required reading by all scientists and graduate students working on cell activation (e.g., growth factors, hormones, and oncogenes).



Lipid Signaling And Metabolism


Lipid Signaling And Metabolism
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Author : James M. Ntambi
language : en
Publisher: Academic Press
Release Date : 2020-08-09

Lipid Signaling And Metabolism written by James M. Ntambi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-09 with Science categories.


Lipid Signaling and Metabolism provides foundational knowledge and methods to examine lipid metabolism and bioactive lipid signaling mediators that regulate a broad spectrum of biological processes and disease states. Here, world-renowned investigators offer a basic examination of general lipid, metabolism, intracellular lipid storage and utilization that is followed by an in-depth discussion of lipid signaling and metabolism across disease areas, including obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders. Throughout, authors demonstrate how expanding our understanding of lipid mediators in metabolism and signaling enables opportunities for novel therapeutics. Emphasis is placed on bioactive lipid metabolism and research that has been impacted by new technologies and their new potential to transform precision medicine. Provides a clear, up-to-date understanding of lipid signaling and metabolism and the impact of recent technologies critical to advancing new studies Empowers researchers to examine bioactive lipid signaling and metabolism, supporting translation to clinical care and precision medicine Discusses the role of lipid signaling and metabolism in obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders, among others



Effects Of Membrane Lipids On Protein Function


Effects Of Membrane Lipids On Protein Function
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Author : Rutilio A. Fratti
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-30

Effects Of Membrane Lipids On Protein Function written by Rutilio A. Fratti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-30 with Science categories.




Membrane Lipid Signaling In Aging And Age Related Disease


Membrane Lipid Signaling In Aging And Age Related Disease
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Author : M.P. Mattson
language : en
Publisher: Elsevier
Release Date : 2003-05-06

Membrane Lipid Signaling In Aging And Age Related Disease written by M.P. Mattson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-06 with Science categories.


The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases. This book provides a comprehensive review of specific membrane lipid mediators and their roles in aging and age-related disease.