Liquid Chromatography Time Of Flight Mass Spectrometry
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Liquid Chromatography Time Of Flight Mass Spectrometry
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Author : Imma Ferrer
language : en
Publisher: John Wiley & Sons
Release Date : 2009-05-06
Liquid Chromatography Time Of Flight Mass Spectrometry written by Imma Ferrer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-06 with Science categories.
Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants—such as antibiotics, steroids, analgesics—using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists, university research chemists, and graduate and post-doctorate students.
Liquid Chromatography Mass Spectrometry Ms Ms And Time Of Flight Ms
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Author : Imma Ferrer
language : en
Publisher: American Chemical Society
Release Date : 2003-08-14
Liquid Chromatography Mass Spectrometry Ms Ms And Time Of Flight Ms written by Imma Ferrer and has been published by American Chemical Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-14 with Language Arts & Disciplines categories.
This volume explores state-of-the-art mass spectrometric techniques. It focuses on liquid chromatography/mass spectrometry/mass spectrometry and time-of-flight/mass spectrometry to determine emerging contaminants, such as pharmaceuticals, hormones, pesticides, surfactants and unknown natural products.
Applications Of Time Of Flight And Orbitrap Mass Spectrometry In Environmental Food Doping And Forensic Analysis
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Author :
language : en
Publisher: Elsevier
Release Date : 2016-06-02
Applications Of Time Of Flight And Orbitrap Mass Spectrometry In Environmental Food Doping And Forensic Analysis written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-02 with Law categories.
Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance. This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants. This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications. This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS. - Provides comprehensive coverage of applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis - Explores a variety of specialized techniques, giving a balanced description of the strengths and weaknesses of each - Presents a general overview of imaging techniques within analysis
Tof Ms Within Food And Environmental Analysis
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Author : Amadeo Rodriguez Fernandez-Alba
language : en
Publisher: Elsevier
Release Date : 2012-08-01
Tof Ms Within Food And Environmental Analysis written by Amadeo Rodriguez Fernandez-Alba and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-01 with Science categories.
New developments in mass spectrometry have allowed routine identification and lowered limits of detection at levels only imagined a decade ago. Thousands of contaminants and residues in the food supply and the environment are now being reported. Between 2005 and 2010, more than 5,000 publications covering TOF-MS and environmental and food analysis were published, showing the importance of the technique in these applications. This book covers the basic principles of method development in GC- and LC-TOF-MS as well as the main operational parameters related to TOF-MS. The second part focuses on the relevant environmental applications, including quality control aspects as well as data collection. The third part is devoted to relevant applications in food analysis, including validation procedures for screening analysis as well as relevant databases. - Outlines basic concepts and principles of gas and liquid chromatography TOF-MS and its application in food analysis - Includes quality control and data collection techniques - Focuses on environmental implications and safety concerns
Principles Of Forensic Toxicology
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Author : Barry Levine
language : en
Publisher: Amer. Assoc. for Clinical Chemistry
Release Date : 2003
Principles Of Forensic Toxicology written by Barry Levine and has been published by Amer. Assoc. for Clinical Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Law categories.
Liquid Chromatography Mass Spectrometry
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Author : Robert E. Ardrey
language : de
Publisher: John Wiley & Sons
Release Date : 2003-04-02
Liquid Chromatography Mass Spectrometry written by Robert E. Ardrey and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-04-02 with Science categories.
Erklärt die Grundprinzipien der LC-MS-Kopplung speziell Beschäftigten im Labor, die diese Technik einsetzen, aber kein umfangreiches chemisches Vorwissen erworben haben. - LC-MS ist ein unentbehrliches Hilfsmittel zur Problemlösung in sämtlichen Gebieten der Analytik, besonders aber zur Trennung und Identifizierung komplexer Gemische organischer oder biologischer Verbindungen - Prinzipien von Flüssigchromatographie (LC) und Massenspektrometrie (MS) werden zunächst einzeln erklärt, Leser muss deshalb nicht auf spezielle Literatur zurückgreifen - Beschreibungen der instrumentellen Ausrüstung sind so anschaulich, dass auch Studenten ohne Zugang zum Labor davon profitieren - moderne Anwendungen der LC-MS und deren Vorteile werden ausführlich besprochen
Targeted Biomarker Quantitation By Lc Ms
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Author : Naidong Weng
language : en
Publisher: John Wiley & Sons
Release Date : 2017-07-31
Targeted Biomarker Quantitation By Lc Ms written by Naidong Weng and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-31 with Medical categories.
The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientists and clinicians for targeted quantitation experiments has experienced explosive growth in recent years. While there are a few books dedicated to bioanalysis and biomarkers in general, until now there were none devoted exclusively to addressing critical issues surrounding this area of intense research. Target Biomarker Quantitation by LC-MS provides a detailed blueprint for quantifying biomarkers in biological systems. It uses numerous real-world cases to exemplify key concepts, all of which were carefully selected and presented so as to allow the concepts they embody to be easily expanded to future applications, including new biomarker development. Target Biomarker Quantitation by LC-MS primarily focuses on the assay establishment for biomarker quantitation—a critical issue rarely treated in depth. It offers comprehensive coverage of three core areas of biomarker assay establishment: the relationship between the measured biomarkers and their intended usage; contemporary regulatory requirements for biomarker assays (a thorough understanding of which is essential to producing a successful and defendable submission); and the technical challenges of analyzing biomarkers produced inside a living organism or cell. Covers the theory of and applications for state-of-the-art mass spectrometry and chromatography and their applications in biomarker analysis Features real-life examples illustrating the challenges involved in target biomarker quantitation and the innovative approaches which have been used to overcome those challenges Addresses potential obstacles to obtain effective biomarker level and data interpretation, such as specificity establishment and sample collection Outlines a tiered approach and fit-for-purpose assay protocol for target biomarker quantitation Highlights the current state of the biomarker regulatory environment and protocol standards Target Biomarker Quantitation by LC-MS is a valuable resource for bioanalytical scientists, drug metabolism and pharmacokinetics scientists, clinical scientists, analytical chemists, and others for whom biomarker quantitation is an important tool of the trade. It also functions as an excellent text for graduate courses in pharmaceutical, biochemistry and chemistry.
Application Of Ic Ms And Ic Icp Ms In Environmental Research
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Author : Rajmund Michalski
language : en
Publisher: John Wiley & Sons
Release Date : 2016-05-20
Application Of Ic Ms And Ic Icp Ms In Environmental Research written by Rajmund Michalski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-20 with Science categories.
Introduces the reader to the field of ion chromatography, species analysis and hyphenated methods IC-MS and IC-ICP-MS including the theory and theirs applications Covers the importance of species analysis and hyphenated methods in ion chromatography Includes practical applications of IC-MS and IC-ICP-MS in environmental analysis Details sample preparation methods for ion chromatography Discusses hyphenated methods IC-MS and IC-ICP-MS used in determining both the total element contents and its elements Details speciation analysis used in studying biochemical cycles of selected chemical compounds; determining toxicity and ecotoxicity of elements; food and pharmaceuticals quality control; and in technological process control and clinical analytics
Chromatographic Techniques In The Forensic Analysis Of Designer Drugs
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Author : Teresa Kowalska
language : en
Publisher: CRC Press
Release Date : 2018-01-31
Chromatographic Techniques In The Forensic Analysis Of Designer Drugs written by Teresa Kowalska and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-31 with Law categories.
There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials. The methods are based on molecular characteristics of the drugs belonging to each individual class of compounds, so it will be clear how the current methods are adaptable to future new drugs that appear in the market.
Mass Spectrometry
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Author : Jürgen H Gross
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-05
Mass Spectrometry written by Jürgen H Gross and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-05 with Science categories.
Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.