Lithographically Defined Silicon Nanowire Field Effect Transistors For Label Free Biosensing
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Lithographically Defined Silicon Nanowire Field Effect Transistors For Label Free Biosensing
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Author : Fern Yuen Yoon
language : en
Publisher:
Release Date : 2008
Lithographically Defined Silicon Nanowire Field Effect Transistors For Label Free Biosensing written by Fern Yuen Yoon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Biosensors categories.
Lithographic Silicon Nanograting Field Effect Transistors As Ultrasensitive Biosensors
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Author : Suresh Kumar Regonda
language : en
Publisher:
Release Date : 2012
Lithographic Silicon Nanograting Field Effect Transistors As Ultrasensitive Biosensors written by Suresh Kumar Regonda and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Biosensors categories.
One dimensional nanostructures have proven to be promising candidates for the development of the advanced biochemical sensors for a variety of applications in health care, drug delivery, bioterrorism, homeland and defense security. Among them, silicon nanowire based FETs (SiNW-FETs) became a potential applicant for ultra -high sensitive label-free electrical biosensors due to their high surface to volume ratio and tunable electrical properties. Top-down approaches like complementary metal-oxide semiconductor (CMOS) compatible technology was opted due to their capability of producing very small and uniform nanowires and to overcome the complex process involved with bottom-up approaches like chemical vapor deposition (CVD) techniques. Despite, very low concentration of protein detection having already been demonstrated using single SiNW-FETs, reliable sensing is still challenging due to unreliable device performance during sensing which is crucial for many practical applications like disease diagnostics.
Functional Nanomaterials And Devices For Electronics Sensors And Energy Harvesting
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Author : Alexei Nazarov
language : en
Publisher: Springer
Release Date : 2014-08-28
Functional Nanomaterials And Devices For Electronics Sensors And Energy Harvesting written by Alexei Nazarov and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-28 with Technology & Engineering categories.
This book contains reviews of recent experimental and theoretical results related to nanomaterials. It focuses on novel functional materials and nanostructures in combination with silicon on insulator (SOI) devices, as well as on the physics of new devices and sensors, nanostructured materials and nano scaled device characterization. Special attention is paid to fabrication and properties of modern low-power, high-performance, miniaturized, portable sensors in a wide range of applications such as telecommunications, radiation control, biomedical instrumentation and chemical analysis. In this book, new approaches exploiting nanotechnologies (such as UTBB FD SOI, Fin FETs, nanowires, graphene or carbon nanotubes on dielectric) to pave a way between “More Moore” and “More than Moore” are considered, in order to create different kinds of sensors and devices which will consume less electrical power, be more portable and totally compatible with modern microelectronics products.
Nanowire Field Effect Transistors Principles And Applications
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Author : Dae Mann Kim
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-23
Nanowire Field Effect Transistors Principles And Applications written by Dae Mann Kim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-23 with Technology & Engineering categories.
“Nanowire Field Effect Transistor: Basic Principles and Applications” places an emphasis on the application aspects of nanowire field effect transistors (NWFET). Device physics and electronics are discussed in a compact manner, together with the p-n junction diode and MOSFET, the former as an essential element in NWFET and the latter as a general background of the FET. During this discussion, the photo-diode, solar cell, LED, LD, DRAM, flash EEPROM and sensors are highlighted to pave the way for similar applications of NWFET. Modeling is discussed in close analogy and comparison with MOSFETs. Contributors focus on processing, electrostatic discharge (ESD) and application of NWFET. This includes coverage of solar and memory cells, biological and chemical sensors, displays and atomic scale light emitting diodes. Appropriate for scientists and engineers interested in acquiring a working knowledge of NWFET as well as graduate students specializing in this subject.
Silicon Nanowire Field Effect Transistor For Biosensing
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Author : Yu Chen
language : en
Publisher:
Release Date : 2009
Silicon Nanowire Field Effect Transistor For Biosensing written by Yu Chen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Abstract: Detection and recognition of chemical ions and biological molecules are important in basic science as well as in pharmacology and medicine. Nanotechnology has made it possible to greatly enhance detection sensitivity through the use of nanowires, nanotubes, nanocrystals, nanocantilevers, and quantum dots as sensing platforms. In this work silicon nanowires are used as the conductance channel between the source and drain of a FET (field effect transistor) device and the biomolecular binding on the surface of nanowire modifies the conductance like a change in gate voltage. Due to the high surface-to-volume ratio and unique character of the silicon nanowires, this device has significant advantages in real-time, label-free and highly sensitive detection of a wide range of species, including proteins, nucleic acids and other small molecules. Here we present a biosensor fabricated from CMOS (complementary metal-oxide-semiconductor) compatible top-down methods including electron beam lithography. This method enables scalable manufacturing of multiple sensor arrays with high efficiency. In a systematic study of the device characteristics with different wire widths, we have found the sensitivity of the device increases when wire width decreases. By operating the device in appropriate bias region, the sensitivity of the device can be improved without doping or high temperature annealing. Not only can this device be used to detect the concentration of proteins and metabolites like urea or glucose, but also dynamic information like the dissociation constant can be extracted from the measurement. The device is also used to detect the clinically related cancer antigen CA 15.3 and shows potential application in cancer studies.
Semiconductor Nanowires
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Author : J Arbiol
language : en
Publisher: Elsevier
Release Date : 2015-03-31
Semiconductor Nanowires written by J Arbiol and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-31 with Technology & Engineering categories.
Semiconductor nanowires promise to provide the building blocks for a new generation of nanoscale electronic and optoelectronic devices. Semiconductor Nanowires: Materials, Synthesis, Characterization and Applications covers advanced materials for nanowires, the growth and synthesis of semiconductor nanowires—including methods such as solution growth, MOVPE, MBE, and self-organization. Characterizing the properties of semiconductor nanowires is covered in chapters describing studies using TEM, SPM, and Raman scattering. Applications of semiconductor nanowires are discussed in chapters focusing on solar cells, battery electrodes, sensors, optoelectronics and biology. Explores a selection of advanced materials for semiconductor nanowires Outlines key techniques for the property assessment and characterization of semiconductor nanowires Covers a broad range of applications across a number of fields
Study Of Silicon Nanowire Field Effect Transistor For Analog And Digital Biosensing
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Author : Pengyuan Zang
language : en
Publisher:
Release Date : 2017
Study Of Silicon Nanowire Field Effect Transistor For Analog And Digital Biosensing written by Pengyuan Zang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Biosensors categories.
The advancement of semiconductor technology has popularized the low power, economical and small form-factor solid state devices, such as those highly integrated and interconnected as the fundamental infrastructure for the internet of things (IoT). Due to its CMOS-compatibility and electrical interface, the biosensor utilizing field effect transistor (FET) as transducer has become the perfect candidate to interface directly with the chemical and biological properties of the physical world. Especially, nanowire (NW) FET biosensor has received great attention as a highly sensitive biosensing platform, benefiting from its increased surface-to-volume ratio. In this work, several challenges and key aspects of existing NW FET biosensor were studied, and solutions were proposed to address these problems. For example, the hydrolytic stability of the surface sensing element was evaluated and improved by a hydrolysis process, which led to a significant increase in the overall biosensor performance. Another challenge is the noise in the electric potential of the sensing solutions. A secondary reference electrode was introduced in the biosensing system, and its potential was used to subtract the noise from the measured sensor output. Compared to a reference FET, this approach greatly reduced the system complexity and requirement, yet still improved the limit of detection (LOD) by 50 – 70%. This work also involved careful investigation into the analyte sensitivity, which can be considerably affected by the charge buffering effect from the surface hydroxyl groups. Analytical studies and numerical simulations were carried out, revealing that both low pH sensitivity and large analyte buffer capacity are required to achieve a reasonable analyte sensitivity. The most significant portion of this work was the experimental demonstration of the digital biosensing concept with single serpentine NW FET biosensor. The majority of existing FET biosensors utilized the device as an analog transducer, which measures the captured analyte density to generate an output, and suffers from various noise factors, especially the nonspecific changes of the sensing solutions than cannot be reduced by averaging. Digital biosensor no longer depends on the amplitude of the sensor output and is therefore better immune from these noise factors. Instead, the individual binding event of single analyte is counted and analyzed statistically to determine the analyte concentration. The single serpentine NW FET is the ideal device design to achieve digital biosensing. It maintains the low noise level with the equivalently long channel, yet achieves a small footprint enough for binding of only a single analyte. The binding of analyte to multiple segments of the NW results in both higher sensitivity and binding avidity. The small footprint also enables high integration density of the individual digital biosensors into an array format, which is a responsive, highly sensitive, and cost-effective future biosensing platform.
Label Free Biosensing
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Author : Michael J. Schöning
language : en
Publisher: Springer
Release Date : 2018-07-20
Label Free Biosensing written by Michael J. Schöning and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-20 with Science categories.
This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field. Highlights of the subjects covered include label-free biosensing with: · semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors · impedimetric biosensors using planar and 3D electrodes · nanocavity and solid-state nanopore devices · carbon nanotube and graphene/graphene oxide biosensors · electrochemical biosensors using molecularly imprinted polymers · biomimetic sensors based on acoustic signal transduction · enzyme logic systems and digital biosensors based on the biocomputing concept · heat-transfer as a novel transducer principle · ultrasensitive surface plasmon resonance biosensors · magnetic biosensors and magnetic imaging devices
Nanowires
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Author : Anqi Zhang
language : en
Publisher: Springer
Release Date : 2016-07-26
Nanowires written by Anqi Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-26 with Technology & Engineering categories.
This book provides a comprehensive summary of nanowire research in the past decade, from the nanowire synthesis, characterization, assembly, to the device applications. In particular, the developments of complex/modulated nanowire structures, the assembly of hierarchical nanowire arrays, and the applications in the fields of nanoelectronics, nanophotonics, quantum devices, nano-enabled energy, and nano-bio interfaces, are focused. Moreover, novel nanowire building blocks for the future/emerging nanoscience and nanotechnology are also discussed.Semiconducting nanowires represent one of the most interesting research directions in nanoscience and nanotechnology, with capabilities of realizing structural and functional complexity through rational design and synthesis. The exquisite control of chemical composition, morphology, structure, doping and assembly, as well as incorporation with other materials, offer a variety of nanoscale building blocks with unique properties.
Novel Fabrication And Operation Of Integrated Silicon Nanowire Field Effect Biosensors For Reliable Detection Of Cancer Prognostic Biomarkers
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Author : Duy Phu Tran
language : en
Publisher:
Release Date : 2014
Novel Fabrication And Operation Of Integrated Silicon Nanowire Field Effect Biosensors For Reliable Detection Of Cancer Prognostic Biomarkers written by Duy Phu Tran and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Biochemical markers categories.
Owning to their unique physicochemical properties, one-dimensional silicon nanowire field effect transistors (SiNW FETs) are widely considered as one of the most promising solid state sensing technology towards the development of ultrasensitive and label-free bio diagnostic devices. While a number of recent studies have focussed on either the investigation of silicon nanowires' structure-function or the demonstration of their capabilities in model studies, integrated and systematic approaches towards their translational implementation as bio-diagnostic sensing technology in clinical environment remains scarce. The ultimate aim of this research was therefore to advance the technology and knowledge of SiNW FET molecular sensing devices through a cross-disciplinary approach combining nanofabrication, nano-electronics, molecular biosensing and clinical oncology.