Longevity And Evolution
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Longevity And Evolution
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Author : Gustavo Barja
language : en
Publisher: Nova Science Publishers
Release Date : 2011-10
Longevity And Evolution written by Gustavo Barja and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10 with Aging categories.
This book reviews research on presently known theories and mechanisms responsible for the rate of ageing and maximum longevity of different animals including birds, mammals and humans (to explain how" do we age and the velocity of the ageing process). In addition, this book deals with the historical evolutionary explanations of ageing and longevity ("why" do we age). The mechanisms discussed include mitochondria and oxygen free radicals, the presence of macromolecules constitutively highly resistant to deleterious modification in the tissues of long-lived animals, insulin/IGF-1 like signalling, telomere shortening, dietary restrictions, and other proposed molecular mechanisms.
Evolution Of Longevity In Animals
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Author : Avril Woodhead
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07
Evolution Of Longevity In Animals written by Avril Woodhead and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.
The analysis of intra-group correlations between LS and BW at representative intervals yields no consistent support for the hypothesis that lower BW is associated with longer LS. Indeed, among male Wistar rats and C57BL/6J and A/J mice followed since weaning on AL diets, the data suggested that relatively higher BW across the adult LS was generally associated with longer life. Even when the diet was restricted by EOD or RES regimens, this pattern of positive correlations between LS and BW persisted for the C57BL/6J and A/J strains when relative ages were analyzed. However, when BW at absolute ages were correlated with LS, support for the positive relationship between BW and LS was not as forthcoming. When AL groups were assessed beginning at later ages (> 10 months), the pattern of positive correlations was very evident for the Wistar rats--heavier rats tended to liver longer. This pattern was also evident among AL-fed C57BL/6J mice followed since 6 months, but was lost in the 10-month group in this strain. Among A/J mice on AL diets, the pattern became somewhat negative when followed at 6 and 10 months of age. However, among both C57BL/6J and A/J mice placed on EOD diets at 6 and 10 months of age, the pattern clearly tended toward the positive.
The Biology Of Human Longevity
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Author : Caleb E. Finch
language : en
Publisher: Elsevier
Release Date : 2010-07-28
The Biology Of Human Longevity written by Caleb E. Finch and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-28 with Medical categories.
Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle. Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists Provides a novel synthesis of existing ideas about the biology of longevity and aging Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition
The Evolution Of Longevity
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Author : Saul Kent
language : en
Publisher:
Release Date : 1980
The Evolution Of Longevity written by Saul Kent and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with categories.
Longevity
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Author : James R. Carey
language : en
Publisher: Princeton University Press
Release Date : 2021-01-12
Longevity written by James R. Carey and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-12 with Science categories.
Despite our deep interest in mortality, little is known about why some individuals live to middle age and others to extreme old age. Life span, mortality, and aging present some of the most profound mysteries in biology. In Longevity, James Carey draws on unprecedented data to develop a biological and demographic framework for identifying the key factors that govern aging, life span, and mortality in humans and other animals. Carey presents the results of a monumental, twelve-year, National Institute on Aging-funded research project on the determinants of longevity using data from the life tables of five million Mediterranean fruit flies, the most comprehensive set of life table studies ever on the mortality dynamics of a single species. He interprets the fruit fly data within the context of human aging and the aging process in general to identify the determinants of mortality. Three key themes emerge: the absence of species-specific life span limits, the context-specific nature of the mortality rate, and biodemographic linkages between longevity and reproduction. A powerful foundation for the emerging field of biodemography and a rich framework for considering the future of human life span, Longevity will be an indispensable resource for readers from a range of fields including population biology, demography, gerontology, ecology, evolutionary biology, and medical research.
Evolution Of Longevity In Animals
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Author : Avril Woodhead
language : en
Publisher: Springer
Release Date : 1987-11-01
Evolution Of Longevity In Animals written by Avril Woodhead and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-11-01 with Medical categories.
The analysis of intra-group correlations between LS and BW at representative intervals yields no consistent support for the hypothesis that lower BW is associated with longer LS. Indeed, among male Wistar rats and C57BL/6J and A/J mice followed since weaning on AL diets, the data suggested that relatively higher BW across the adult LS was generally associated with longer life. Even when the diet was restricted by EOD or RES regimens, this pattern of positive correlations between LS and BW persisted for the C57BL/6J and A/J strains when relative ages were analyzed. However, when BW at absolute ages were correlated with LS, support for the positive relationship between BW and LS was not as forthcoming. When AL groups were assessed beginning at later ages (> 10 months), the pattern of positive correlations was very evident for the Wistar rats--heavier rats tended to liver longer. This pattern was also evident among AL-fed C57BL/6J mice followed since 6 months, but was lost in the 10-month group in this strain. Among A/J mice on AL diets, the pattern became somewhat negative when followed at 6 and 10 months of age. However, among both C57BL/6J and A/J mice placed on EOD diets at 6 and 10 months of age, the pattern clearly tended toward the positive.
Human Longevity
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Author : Raymond C. Valentine
language : en
Publisher: CRC Press
Release Date : 2014-09-18
Human Longevity written by Raymond C. Valentine and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-18 with Medical categories.
More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised vers
The Evolution Of Aging
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Author : Theodore C. Goldsmith
language : en
Publisher: Azinet
Release Date : 2006
The Evolution Of Aging written by Theodore C. Goldsmith and has been published by Azinet this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Aging categories.
Goldsmith provides a historical review of biological aging theories including underlying evolution and genetics issues and describes exciting recent discoveries and new theories that are causing renewed interest in aging-by-design.
Evolution Of Human Longevity
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Author : Richard G. Cutler
language : en
Publisher:
Release Date : 1980
Evolution Of Human Longevity written by Richard G. Cutler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with categories.
The Long And The Short Of It
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Author : Jonathan Silvertown
language : en
Publisher: University of Chicago Press
Release Date : 2013-11-01
The Long And The Short Of It written by Jonathan Silvertown and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-01 with Science categories.
“[A] whimsical book on aging . . . the author mixes art, science, and humor to brew a highly readable concoction, presenting one aging theory after another.” —Publishers Weekly Everything that lives will die. That’s the fundamental fact of life. But not everyone dies at the same age: people vary wildly in their patterns of aging and their life spans—and that variation is nothing compared to what’s found in other animal and plant species. With The Long and the Short of It, biologist and writer Jonathan Silvertown offers readers a witty and fascinating tour through the scientific study of longevity and aging. Dividing his daunting subject by theme—death, life span, aging, heredity, evolution, and more—Silvertown draws on the latest scientific developments to paint a picture of what we know about how life span, senescence, and death vary within and across species. At every turn, he addresses fascinating questions that have far-reaching implications: What causes aging, and what determines the length of an individual life? What changes have caused the average human life span to increase so dramatically—fifteen minutes per hour—in the past two centuries? If evolution favors those who leave the most descendants, why haven’t we evolved to be immortal? The answers to these puzzles and more emerge from close examination of the whole natural history of life span and aging, from fruit flies, nematodes, redwoods, and much more. The Long and the Short of It pairs a perpetually fascinating topic with a wholly engaging writer, and the result is a supremely accessible book that will reward curious readers of all ages. “Captivating and enlightening.” —The New York Times Well Blog