The Evolution Of Longevity
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The Evolution Of Longevity
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Author : Saul Kent
language : en
Publisher:
Release Date : 1980
The Evolution Of Longevity written by Saul Kent and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with categories.
Evolution Of Longevity In Animals
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Author : Avril Woodhead
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07
Evolution Of Longevity In Animals written by Avril Woodhead and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.
The analysis of intra-group correlations between LS and BW at representative intervals yields no consistent support for the hypothesis that lower BW is associated with longer LS. Indeed, among male Wistar rats and C57BL/6J and A/J mice followed since weaning on AL diets, the data suggested that relatively higher BW across the adult LS was generally associated with longer life. Even when the diet was restricted by EOD or RES regimens, this pattern of positive correlations between LS and BW persisted for the C57BL/6J and A/J strains when relative ages were analyzed. However, when BW at absolute ages were correlated with LS, support for the positive relationship between BW and LS was not as forthcoming. When AL groups were assessed beginning at later ages (> 10 months), the pattern of positive correlations was very evident for the Wistar rats--heavier rats tended to liver longer. This pattern was also evident among AL-fed C57BL/6J mice followed since 6 months, but was lost in the 10-month group in this strain. Among A/J mice on AL diets, the pattern became somewhat negative when followed at 6 and 10 months of age. However, among both C57BL/6J and A/J mice placed on EOD diets at 6 and 10 months of age, the pattern clearly tended toward the positive.
The Biology Of Human Longevity
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Author : Caleb E. Finch
language : en
Publisher: Elsevier
Release Date : 2010-07-28
The Biology Of Human Longevity written by Caleb E. Finch and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-28 with Medical categories.
Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle. Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists Provides a novel synthesis of existing ideas about the biology of longevity and aging Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition
Evolution Of Longevity In Animals
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Author : Avril Woodhead
language : en
Publisher: Springer
Release Date : 1987-11-01
Evolution Of Longevity In Animals written by Avril Woodhead and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-11-01 with Medical categories.
The analysis of intra-group correlations between LS and BW at representative intervals yields no consistent support for the hypothesis that lower BW is associated with longer LS. Indeed, among male Wistar rats and C57BL/6J and A/J mice followed since weaning on AL diets, the data suggested that relatively higher BW across the adult LS was generally associated with longer life. Even when the diet was restricted by EOD or RES regimens, this pattern of positive correlations between LS and BW persisted for the C57BL/6J and A/J strains when relative ages were analyzed. However, when BW at absolute ages were correlated with LS, support for the positive relationship between BW and LS was not as forthcoming. When AL groups were assessed beginning at later ages (> 10 months), the pattern of positive correlations was very evident for the Wistar rats--heavier rats tended to liver longer. This pattern was also evident among AL-fed C57BL/6J mice followed since 6 months, but was lost in the 10-month group in this strain. Among A/J mice on AL diets, the pattern became somewhat negative when followed at 6 and 10 months of age. However, among both C57BL/6J and A/J mice placed on EOD diets at 6 and 10 months of age, the pattern clearly tended toward the positive.
Longevity And Evolution
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Author : Gustavo Barja
language : en
Publisher: Nova Science Publishers
Release Date : 2011-10
Longevity And Evolution written by Gustavo Barja and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10 with Aging categories.
This book reviews research on presently known theories and mechanisms responsible for the rate of ageing and maximum longevity of different animals including birds, mammals and humans (to explain how" do we age and the velocity of the ageing process). In addition, this book deals with the historical evolutionary explanations of ageing and longevity ("why" do we age). The mechanisms discussed include mitochondria and oxygen free radicals, the presence of macromolecules constitutively highly resistant to deleterious modification in the tissues of long-lived animals, insulin/IGF-1 like signalling, telomere shortening, dietary restrictions, and other proposed molecular mechanisms.
Longevity Senescence And The Genome
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Author : Caleb E. Finch
language : en
Publisher: University of Chicago Press
Release Date : 1994-05-16
Longevity Senescence And The Genome written by Caleb E. Finch and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-05-16 with Health & Fitness categories.
Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging. To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.
Brain And Longevity
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Author : Caleb E. Finch
language : en
Publisher: Springer
Release Date : 2013-12-21
Brain And Longevity written by Caleb E. Finch and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-21 with Medical categories.
In this third volume on longevity Fondation Ipsen has again collected the most recent results in research on genes and diet in the evolution of human longevity, educational level and longevity, cognitive impairment and survival at older age and other contributions. The preponderance of relatively short - compared to long-lived organisms suggests that morphogenesis is easier to accomplish than is maintenace of soma, whereas the broad range of longevities of organisms demonstrates that maintaining soma for extended periods of time is possible. The underlying assumption of "disposable soma" theory of aging is that the expense of maintaining somatic cells depends on their contribution to the welfare of the germ cells.
The Evolution Of Senescence In The Tree Of Life
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Author :
language : en
Publisher:
Release Date : 2017
The Evolution Of Senescence In The Tree Of Life written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Aging categories.
Longevity
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Author : James R. Carey
language : en
Publisher: Princeton University Press
Release Date : 2003-03-02
Longevity written by James R. Carey and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-02 with Family & Relationships categories.
Despite our deep interest in mortality, little is known about why some individuals live to middle age and others to extreme old age. Life span, mortality, and aging present some of the most profound mysteries in biology. In Longevity, James Carey draws on unprecedented data to develop a biological and demographic framework for identifying the key factors that govern aging, life span, and mortality in humans and other animals. Carey presents the results of a monumental, twelve-year, National Institute on Aging-funded research project on the determinants of longevity using data from the life tables of five million Mediterranean fruit flies, the most comprehensive set of life table studies ever on the mortality dynamics of a single species. He interprets the fruit fly data within the context of human aging and the aging process in general to identify the determinants of mortality. Three key themes emerge: the absence of species-specific life span limits, the context-specific nature of the mortality rate, and biodemographic linkages between longevity and reproduction. A powerful foundation for the emerging field of biodemography and a rich framework for considering the future of human life span, Longevity will be an indispensable resource for readers from a range of fields including population biology, demography, gerontology, ecology, evolutionary biology, and medical research.
The Evolution Of Aging
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Author : Theodore C. Goldsmith
language : en
Publisher: Azinet
Release Date : 2006
The Evolution Of Aging written by Theodore C. Goldsmith and has been published by Azinet this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Aging categories.
Goldsmith provides a historical review of biological aging theories including underlying evolution and genetics issues and describes exciting recent discoveries and new theories that are causing renewed interest in aging-by-design.