Macromolecular Crystallography Protocols
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Macromolecular Crystallography Protocols Volume 1
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Author : Sylvie Doublie
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
Macromolecular Crystallography Protocols Volume 1 written by Sylvie Doublie and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.
Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1, Preparation and Crystallization of Macromolecules and Volume 2, Structure Determination, explore recent advances that have accelerated the pace of structural determination and made crystallography accessible to a broader range of investigators. Volume 1 is composed of detailed protocols for the preparation and optimization of crystals, including tips from the experts on the best methods for inducing proteins to adopt their crystalline form. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization, as well as computational techniques for data collection, phasing, and refinement. The volume concludes with a detailed and insightful survey of available crystallographic software. These volumes will be an indispensable reference for obtaining macromolecular crystals and determining their three-dimensional structure.
Macromolecular Crystallography Protocols Volume 2
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Author : Sylvie Doublie
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05
Macromolecular Crystallography Protocols Volume 2 written by Sylvie Doublie and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Science categories.
In the decade since publication of the first edition of Crystallographic Methods and Protocols the field has seen several major developments that have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. Volume I, Preparation and Crystallization of Macromolecules is dedicated to the crystallization and ways to increase the odds of obtaining crystals in macromolecules, while Volume 2, Structure Determination, covers both computational methods for characterizing crystals and solving structures.
Macromolecular Crystallography Protocols
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Author : Sylvie Doublié
language : en
Publisher:
Release Date : 2007
Macromolecular Crystallography Protocols written by Sylvie Doublié and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
In the decade since publication of the first edition of "Crystallographic Methods and Protocols", the field has seen several major developments that have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. Volume I, "Preparation and Crystallization of Macromolecules" is dedicated to the crystallization and ways to increase the odds of obtaining crystals in macromolecules, while Volume 2, "Structure Determination", covers both computational methods for characterizing crystals and solving structures.
Macromolecular Crystallography Protocols Volume 1
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Author : Sylvie Doublie
language : en
Publisher: Humana Press
Release Date : 2010-11-10
Macromolecular Crystallography Protocols Volume 1 written by Sylvie Doublie and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-10 with Science categories.
Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1 is composed of detailed protocols for the preparation and optimization of crystals. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization. The volume concludes with a survey of available crystallographic software.
Macromolecular Crystallography Protocols
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Author : Sylvie Doublié
language : en
Publisher:
Release Date : 2007
Macromolecular Crystallography Protocols written by Sylvie Doublié and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Crystallography categories.
Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1, Preparation and Crystallization of Macromolecules and Volume 2, Structure Determination, explore recent advances that have accelerated the pace of structural determination and made crystallography accessible to a broader range of investigators. Volume 1 is composed of detailed protocols for the preparation and optimization of crystals, including tips from the experts on the best methods for inducing proteins to adopt their crystalline form. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization, as well as computational techniques for data collection, phasing, and refinement. The volume concludes with a detailed and insightful survey of available crystallographic software. These volumes will be an indispensable reference for obtaining macromolecular crystals and determining their three-dimensional structure.
Protein Crystallography
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Author : Alexander Wlodawer
language : en
Publisher:
Release Date : 2017
Protein Crystallography written by Alexander Wlodawer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Life sciences categories.
Macromolecular Crystallography Protocols
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Author : Sylvie Doublié
language : en
Publisher:
Release Date : 2007
Macromolecular Crystallography Protocols written by Sylvie Doublié and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
In the decade since the publication of the first edition of "Crystallographic Methods and Protocols", the field has seen several major developments that have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. "Volume I, Preparation and Crystallization of Macromolecules" is dedicated to the crystallization and ways to increase the odds of obtaining crystals in macromolecules, while "Volume 2, Structure Determination" covers both computational methods for characterizing crystals and solving structures.
Mass Spectrometry Data Analysis In Proteomics
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Author : Rune Matthiesen
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Mass Spectrometry Data Analysis In Proteomics written by Rune Matthiesen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Science categories.
Mass Spectrometry Data Analysis in Proteomics is an in-depth guide to the theory and practice of analyzing raw mass spectrometry (MS) data in proteomics. As MS is a high throughput technique, proteomic researchers must attend carefully to the associated field of data analysis, and this volume outlines available bioinformatics programs, algorithms, and databases available for MS data analysis. General guidelines for data analysis using search engines such as Mascot, Xtandem, and VEMS are provided, with specific attention to identifying poor quality data and optimizing search parameters. Several different types of MS data are discussed, followed by a description of optimal methods for conversion of raw data into peak lists for input to search engines. Choosing the most accurate and complete databases is emphasized, and a report of available sequence databases is included. Methods for assembling expressed sequence tags (ESTs) into assembled nonredundant databases are provided, along with protocols for further processing the sequences into a format suitable for MS data. Mass Spectrometry Data Analysis in Proteomics describes publicly available applications whenever possible.
Biomolecular Crystallography
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Author : Bernhard Rupp
language : en
Publisher: Garland Science
Release Date : 2009-10-20
Biomolecular Crystallography written by Bernhard Rupp and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-20 with Science categories.
Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics.
Macromolecular Crystallography
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Author : Mark R. Sanderson
language : en
Publisher: OUP Oxford
Release Date : 2007-08-23
Macromolecular Crystallography written by Mark R. Sanderson and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-23 with Science categories.
Macromolecular Crystallography is the study of macromolecules (proteins and nucleic acids) using X-ray crystallographic techniques in order to determine their molecular structure. The knowledge of accurate molecular structures is a pre-requisite for rational drug design, and for structure-based function studies to aid the development of effective therapeutic agents and drugs. The successful determination of the complete genome (genetic sequence) of several species (including humans) has recently directed scientific attention towards identifying the structure and function of the complete complement of proteins that make up that species; a new and rapidly growing field of study called 'structural genomics'. There are now several important and well-funded global initiatives in operation to identify all of the proteins of key model species. One of the main requirements for these initiatives is a high-throughput crystallization facility to speed-up the protein identification process. The extent to which these technologies have advanced, calls for an updated review of current crystallographic theory and practice. This practical reference book features the latest conventional and high-throughput methods, and includes contributions from a team of internationally recognized leaders and experts. It will be of relevance and use to graduate students, research scientists and professionals currently working in the field of conventional and high-throughput macromolecular crystallography.