Mammalian Cell Biotechnology In Protein Production
DOWNLOAD
Download Mammalian Cell Biotechnology In Protein Production PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Mammalian Cell Biotechnology In Protein Production book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Mammalian Cell Biotechnology In Protein Production
DOWNLOAD
Author : Hansjörg Hauser
language : en
Publisher: Walter de Gruyter
Release Date : 2011-07-13
Mammalian Cell Biotechnology In Protein Production written by Hansjörg Hauser and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-13 with Science categories.
„Hauser und Wagner haben die neuen Möglichkeiten der Mammalian Cell Biology sehr anregend dargestellt.“ Prof. Dr. Hans Fritz, Ludwig-Maximilians-Universität München
Cell Culture Engineering
DOWNLOAD
Author : Gyun Min Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2020-01-13
Cell Culture Engineering written by Gyun Min Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-13 with Science categories.
Offers a comprehensive overview of cell culture engineering, providing insight into cell engineering, systems biology approaches and processing technology In Cell Culture Engineering: Recombinant Protein Production, editors Gyun Min Lee and Helene Faustrup Kildegaard assemble top class authors to present expert coverage of topics such as: cell line development for therapeutic protein production; development of a transient gene expression upstream platform; and CHO synthetic biology. They provide readers with everything they need to know about enhancing product and bioprocess attributes using genome-scale models of CHO metabolism; omics data and mammalian systems biotechnology; perfusion culture; and much more. This all-new, up-to-date reference covers all of the important aspects of cell culture engineering, including cell engineering, system biology approaches, and processing technology. It describes the challenges in cell line development and cell engineering, e.g. via gene editing tools like CRISPR/Cas9 and with the aim to engineer glycosylation patterns. Furthermore, it gives an overview about synthetic biology approaches applied to cell culture engineering and elaborates the use of CHO cells as common cell line for protein production. In addition, the book discusses the most important aspects of production processes, including cell culture media, batch, fed-batch, and perfusion processes as well as process analytical technology, quality by design, and scale down models. -Covers key elements of cell culture engineering applied to the production of recombinant proteins for therapeutic use -Focuses on mammalian and animal cells to help highlight synthetic and systems biology approaches to cell culture engineering, exemplified by the widely used CHO cell line -Part of the renowned "Advanced Biotechnology" book series Cell Culture Engineering: Recombinant Protein Production will appeal to biotechnologists, bioengineers, life scientists, chemical engineers, and PhD students in the life sciences.
Recombinant Protein Expression In Mammalian Cells
DOWNLOAD
Author : David L. Hacker
language : en
Publisher: Humana
Release Date : 2024-08-17
Recombinant Protein Expression In Mammalian Cells written by David L. Hacker and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-17 with Science categories.
This fully updated volume explores notable developments in the field of mammalian cell-based recombinant protein production. Beginning with methods for transient recombinant protein production, the book continues with methods for stable cell pool generation, protein production using stable clonal cell lines, as well as high-throughput screening technologies for characterizing transient cell surface protein ectodomain expression and for identifying host genes involved in protein production. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Recombinant Protein Expression in Mammalian Cells: Methods and Protocols, Second Edition serves as an ideal guide for researchers investigatingprotein structure and function and accelerating the discovery of new therapeutic proteins.
Animal Cell Biotechnology
DOWNLOAD
Author : Ralf Pörtner
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-04-05
Animal Cell Biotechnology written by Ralf Pörtner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-05 with Science categories.
The second edition of this book constitutes a comprehensive manual of new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture considering the whole cascade from lab to final production. The chapters are written by world-renowned experts and the volume’s five parts reflect the processes required for different stages of production. This book is a compendium of techniques for scientists in both industrial and research laboratories that use mammalian cells for biotechnology purposes.
Mammalian Cell Biotechnology
DOWNLOAD
Author : Michael Butler
language : en
Publisher: Oxford University Press
Release Date : 1991
Mammalian Cell Biotechnology written by Michael Butler and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Animal cell biotechnology. categories.
The development of mammalian cell biotechnology has led to an extensive range of compounds which can be routinely produced by cell culture. This book details the principles and practical techniques upon which this development is based.
Large Scale Mammalian Cell Culture Technology
DOWNLOAD
Author : Lubiniecki
language : en
Publisher: Routledge
Release Date : 2018-05-02
Large Scale Mammalian Cell Culture Technology written by Lubiniecki and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-02 with Medical categories.
An interdisciplinary approach, integrating biochemistry, biology, genetics, and engineering for the effective production of protein pharmaceuticals. The volume offers a biological perspective of large-scale animal cell culture and examines diverse processing strategies, process management, regulator
Mammalian Cell Cultures For Biologics Manufacturing
DOWNLOAD
Author : Weichang Zhou
language : en
Publisher: Springer
Release Date : 2014-01-15
Mammalian Cell Cultures For Biologics Manufacturing written by Weichang Zhou and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with Science categories.
Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Animal Cell Culture
DOWNLOAD
Author : Mohamed Al-Rubeai
language : en
Publisher: Springer
Release Date : 2014-11-28
Animal Cell Culture written by Mohamed Al-Rubeai and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-28 with Medical categories.
Animal cells are the preferred “cell factories” for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They are used for the production of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV, arthritis, cardiovascular and CNS diseases and cystic fibrosis. Animal cells are used as in vitro substrates in pharmacological and toxicological studies. This book is designed to serve as a comprehensive review of animal cell culture, covering the current status of both research and applications. For the student or R&D scientist or new researcher the protocols are central to the performance of cell culture work, yet a broad understanding is essential for translation of laboratory findings into the industrial production. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field to produce state-of-the-art collection of current research. A major reference volume on cell culture research and how it impacts on production of biopharmaceutical proteins worldwide, the book is essential reading for everyone working in cell culture and is a recommended volume for all biotechnology libraries.
Protein Expression In Mammalian Cells
DOWNLOAD
Author : James L Hartley
language : en
Publisher: Humana Press
Release Date : 2011-10-12
Protein Expression In Mammalian Cells written by James L Hartley and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-12 with Science categories.
Through all of the recent progress provided by high throughput DNA sequencing technologies, it has become clearer and clearer that the study of proteins and protein organelles will be the key to unlocking our ability to manipulate cells and intervene in human disease. In Protein Expression in Mammalian Cells: Methods and Protocols, expert researchers in the field present a compendium of vital techniques to further our knowledge of mammalian protein expression. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and concise, Protein Expression in Mammalian Cells: Methods and Protocols will aid scientists seeking to delve deeper into our own biology through the medium of other mammalian cells and proteins.
Cell Culture Engineering
DOWNLOAD
Author : Wei-Shu Hu
language : en
Publisher: Springer
Release Date : 2006-08-16
Cell Culture Engineering written by Wei-Shu Hu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-16 with Science categories.
Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.