Management Of Dysregulated Immune Response In The Critically Ill
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Management Of Dysregulated Immune Response In The Critically Ill
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Author : Zsolt Molnar
language : en
Publisher: Springer Nature
Release Date : 2023-03-11
Management Of Dysregulated Immune Response In The Critically Ill written by Zsolt Molnar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-11 with Medical categories.
This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.
Post Intensive Care Syndrome
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Author : Jean-Charles Preiser
language : en
Publisher: Springer Nature
Release Date : 2019-08-31
Post Intensive Care Syndrome written by Jean-Charles Preiser and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-31 with Medical categories.
This book, part of the European Society of Intensive Care Medicine textbook series, provides detailed up-to-date information on the physical, cognitive, and psychological impairments that are frequently present following a stay in an intensive care unit and examines in depth the available preventive and therapeutic strategies, including adapted rehabilitation programs. Beyond acquainting readers with the multiple facets of post-intensive care syndrome (PICS), the book aims to promote the effective follow-up of patients, thereby enhancing their ability to work and their functional autonomy, and to identify risk factors for the development of PICS as a stimulus to beneficial organizational changes in intensive care departments. The background to the book is the realization by healthcare providers that the quality of life of patients who have required a stay in an intensive care unit can be severely impaired or even become unacceptable. All too often, the diverse sequelae are overlooked by specialists of other disciplines. Moreover, families and caregivers are also at high risk of post-traumatic stress disorder and depression. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care. This book, written by renowned experts in the field, will facilitate the transmission of key knowledge with significant clinical and financial benefits.
Stress Challenges And Immunity In Space
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Author : Alexander Choukèr
language : en
Publisher: Springer Nature
Release Date : 2019-11-27
Stress Challenges And Immunity In Space written by Alexander Choukèr and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-27 with Medical categories.
This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Covid 19 Airway Management And Ventilation Strategy For Critically Ill Older Patients
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Author : Nicola Vargas
language : en
Publisher: Springer Nature
Release Date : 2020-08-25
Covid 19 Airway Management And Ventilation Strategy For Critically Ill Older Patients written by Nicola Vargas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-25 with Medical categories.
This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the Covid-19 pandemic, and offers practical information on how to manage them. Older adults are more susceptible to complications such as acute respiratory distress syndrome (ARDS) as a result of viral pneumonia. In addition, they often have multiple comorbidities and are commonly frail, which means their various organs and systems, such as the respiratory system, have reduced functional reserves. As such, older adults are less able to react to acute stressors. During the current Covid-19 pandemic, older adult patients' mortality is increased. Further, the infection and death rates of elderly people in nursing homes and health care institutions are high. Management of older adults with Covid is complicated. The reduced availability of beds may limit their access to ICU. Moreover, the prognosis may be poor, and airway management and ventilation strategies have to take into account various clinical and physiological characteristics specific to older patients. This book is addressed to all allied professionals involved in the management of older critically ill patients and presents information collected and practical lessons learned from the clinical daily management of this population during the pandemic.
The Washington Manual Of Critical Care
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Author : Marin Kollef
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2024-06-30
The Washington Manual Of Critical Care written by Marin Kollef and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-30 with Medical categories.
Part of the popular Washington Manual® handbook series, The Washington Manual® of Critical Care provides concise, high-yield content that reflects today’s fast-changing advances in the field. Edited by Drs. Marin H. Kollef, Vladimir N. Despotovic, Bryan D. Kraft, Rachel K. McDonald, and Nguyet Nguyen, and written by teams of Washington University residents and faculty, the fourth edition focuses on the essential information you need to know, using a brief, bulleted format, along with numerous figures, tables, algorithms, and images throughout. In one convenient, portable resource, you’ll find complete coverage of bedside diagnosis and management of the most frequently encountered illnesses and problems seen in the ICU—all at your fingertips for quick review and reference.
Coronavirus Disease Covid 19 Pathophysiology Epidemiology Clinical Management And Public Health Response Volume I C
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Author : Zisis Kozlakidis
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-25
Coronavirus Disease Covid 19 Pathophysiology Epidemiology Clinical Management And Public Health Response Volume I C written by Zisis Kozlakidis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-25 with Medical categories.
Volume I.C An outbreak of a respiratory disease first reported in Wuhan, China in December 2019 and the causative agent was discovered in January 2020 to be a novel betacoronovirus of the same subgenus as SARS-CoV and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) has rapidly disseminated worldwide, with clinical manifestations ranging from mild respiratory symptoms to severe pneumonia and a fatality rate estimated around 2%. Person to person transmission is occurring both in the community and healthcare settings. The World Health Organization (WHO) has recently declared the COVID-19 epidemic a public health emergency of international concern. The ongoing outbreak presents many clinical and public health management challenges due to limited understanding of viral pathogenesis, risk factors for infection, natural history of disease including clinical presentation and outcomes, prognostic factors for severe illness, period of infectivity, modes and extent of virus inter-human transmission, as well as effective preventive measures and public health response and containment interventions. There are no antiviral treatment nor vaccine available but fast track research and development efforts including clinical therapeutic trials are ongoing across the world. Managing this serious epidemic requires the appropriate deployment of limited human resources across all cadres of health care and public health staff, including clinical, laboratory, managerial and epidemiological data analysis and risk assessment experts. It presents challenges around public communication and messaging around risk, with the potential for misinformation and disinformation. Therefore, integrated operational research and intervention, learning from experiences across different fields and settings should contribute towards better understanding and managing COVID-19. This Research Topic aims to highlight interdisciplinary research approaches deployed during the COVID-19 epidemic, addressing knowledge gaps and generating evidence for its improved management and control. It will incorporate critical, theoretically informed and empirically grounded original research contributions using diverse approaches, experimental, observational and intervention studies, conceptual framing, expert opinions and reviews from across the world. The Research Topic proposes a multi-dimensional approach to improving the management of COVID-19 with scientific contributions from all areas of virology, immunology, clinical microbiology, epidemiology, therapeutics, communications as well as infection prevention and public health risk assessment and management studies.
The Very Old Critically Ill Patients
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Author : Hans Flaatten
language : en
Publisher: Springer Nature
Release Date : 2022-08-03
The Very Old Critically Ill Patients written by Hans Flaatten and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-03 with Medical categories.
This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, provides detailed up-to-date information on the care of the critical ill very old (≥80 years) patients in the ICU. The very old are expanding fast in our populations, and this is mirrored in our hospitals and ICUs as well. During the last decade, a lot more information about the group of critical ill elderly has been published, and several large networks cooperate in performing multinational studies in this field, one of them with roots in the ESICM. This book will give readers knowledge about the current epidemiology of elderly ICU patients, in patients centered outcomes and factors affecting these outcomes. A large part is devoted to age related changes in vital organ functions, and the specific geriatric “syndromes” like frailty, cognitive decline, reduced activity of daily living, sarcopenia and immunosenecence. This is all important for the practicing intensivists to know about. In addition, specific groups of the elderly in the ICU are also described like the elderly patients with trauma or sepsis. The book is written jointly by intensivists and geriatricians, often working in teams and originating from many different countries. This herald a new era in the collaboration between these two groups in order to improve care and rehabilitation. We have a lot to learn from each other, as both groups have a holistic view of our patients although with different perspectives. This book should be of value for all working in adult ICUs, physicians as well as nurses. It will hopefully lead to a better understanding of the particular challenges posed by this important sub-group of ICU patients and how to manage his group in a way that combine respect for life as well as death and includes patients and caregivers in this process.
Sepsis Management In Resource Limited Settings
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Author : Arjen M. Dondorp
language : en
Publisher: Springer
Release Date : 2019-02-08
Sepsis Management In Resource Limited Settings written by Arjen M. Dondorp and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-08 with Medical categories.
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.
Textbook Of Polytrauma Management
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Author : Hans-Christoph Pape
language : en
Publisher: Springer Nature
Release Date : 2022-05-31
Textbook Of Polytrauma Management written by Hans-Christoph Pape and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-31 with Medical categories.
This textbook is a fully updated and revised third edition of a highly successful practical guide to the care of the polytrauma patient. Broadening its readership to students, this new edition comprehensively describes the clinical course of multiple and severe injuries, from the accident scene to rehabilitation. It provides essential practical information on the care of patients both with blunt and penetrating trauma to multiple body regions, and discusses the management of truncal injuries (head, chest, abdomen) as well as fractures of the extremities, pelvis and spine. Further, the book highlights associated injuries that may alter decisions concerning patients with polytrauma. This new, revised edition takes full account of recent developments, including the increasing economic pressure on health care systems, prehospital treatment, changes in trauma systems and related education, and the improved survival of polytrauma patients. Also covering improved monitoring options along with issues in late patient outcomes and rehabilitation this work will greatly assist students, emergency personnel, trauma surgeons, orthopaedic traumatologists, and anesthesiologists.
Small Animal Critical Care Medicine E Book
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Author : Deborah Silverstein
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-06-15
Small Animal Critical Care Medicine E Book written by Deborah Silverstein and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-15 with Medical categories.
Small Animal Critical Care Medicine is a comprehensive, concise guide to critical care, encompassing not only triage and stabilization, but also the entire course of care during the acute medical crisis and high-risk period. This clinically oriented manual assists practitioners in providing the highest standard of care for ICU patients."The second edition of Small Animal Critical Care Medicine should be somewhere in everyone’s clinic, whether a first-line practice or a specialized clinic."Reviewed by: Kris Gommeren on behalf of the European Journal of Companion Animal Practice, Oct 2015 Over 200 concise chapters are thoroughly updated to cover all of the clinical areas needed for evaluating, diagnosing, managing, and monitoring a critical veterinary patient. More than 150 recognized experts offer in-depth, authoritative guidance on emergency and critical care clinical situations from a variety of perspectives. A problem-based approach focuses on clinically relevant details. Practical, user-friendly format makes reference quick and easy with summary tables, boxes highlighting key points, illustrations, and algorithmic approaches to diagnosis and management. Hundreds of full-color illustrations depict various emergency procedures such as chest tube placement. Appendices offer quick access to the most often needed calculations, conversion tables, continuous rate infusion determinations, reference ranges, and more. All-NEW chapters include Minimally Invasive Diagnostics and Therapy, T-FAST and A-FAST, Systemic Inflammatory Response Syndrome (SIRS), Multiple Organ Dysfunction Syndrome (MODS), Sepsis, Physical Therapy Techniques, ICU Design and Management, and Communication Skills and Grief Counseling. NEW! Coverage of basic and advanced mechanical ventilation helps you in deliver high-quality care to patients with respiratory failure. NEW! Coverage of increasingly prevalent problems seen in the Intensive Care Unit includes multidrug-resistant bacterial infections and coagulation disorders. NEW chapters on fluid therapy and transfusion therapy provide information on how to prevent complications and maximize resources. UPDATED coagulation section includes chapters on hypercoagulability, platelet function and testing, anticoagulant therapy, and hemostatic drugs.