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Marine Glycomics


Marine Glycomics
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Marine Glycomics


Marine Glycomics
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Author : Yuki Fujii
language : en
Publisher:
Release Date : 2022

Marine Glycomics written by Yuki Fujii and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.


Marine creatures are rich sources of glycoconjugate-containing glycans and have diversified structures. The advance of genomics has provided a valuable clue for their production and developments. This information will encourage breeding and engineering functional polysaccharides with slime ingredients in algae. These glycans will have the potential for applications to antioxidant, anticancer, and antimicrobial drugs in addition to health supplements and cosmetics. The combination of both biochemical and transcriptome approaches of marine creatures will lead to the opportunity to discover new activities of proteins such as glycan-relating enzymes and lectins. These proteins will also be used for experimental and medical purposes, such as diagnostics and trial studies. The topic of marine glycomics is also focusing on understanding the physiological properties of marine creatures, such as body defense against pathogens and cancers. In the competitions for natural selection, living creatures have evolved both their glycans and their recognition. They have primitive systems of immunity, and few of their mechanisms are closely related to glycans. If we are able to describe the accumulation of data of glycans of creatures living in the seashore and the oceans, we may be able to anticipate a time when we can talk about the ecosystem with glycans. That knowledge will be useful for the development of drugs that cure our diseases and for an understanding of living systems in addition to the preservation of living environments.



Marine Glycobiology Glycomics And Lectins


Marine Glycobiology Glycomics And Lectins
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Author : Yasuhiro Ozeki
language : en
Publisher: MDPI
Release Date : 2019-11-20

Marine Glycobiology Glycomics And Lectins written by Yasuhiro Ozeki and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-20 with Medical categories.


Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”—that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences. This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined.



Marine Medicinal Glycomics


Marine Medicinal Glycomics
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Author : Vitor H. Pomin
language : en
Publisher: Nova Science Publishers
Release Date : 2013

Marine Medicinal Glycomics written by Vitor H. Pomin and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Chitin categories.


Glycomics is an international project that analyses systematically and comparatively the overall and/or specific structural and biological properties of carbohydrates, also known as sugars or glycans, within a repertoire from a given type of cell, tissue, organism, kingdom, or even from a certain environment, as found under specific conditions. Glycomics is one of the latest omics projects to be launched into biology. This was because carbohydrates had been primarily considered as a mere class of structural or energetic molecules. Besides that, structural and functional studies in glycomics are more challenging than other projects, and analytical limitations in glycobiology have impaired the progress. However, with the development of technology, and mostly through recent scientific achievements, innumerous vital biological functions have been uncovered and attributed to the sugars. Moreover, certain glycans may also exhibit effective medicinal properties which have in turn awakened a great interest by pharmaceutical companies.This book compiles and illustrates some of these recent achievements concerning the principle examples of marine sugars with medical properties, such as chitin, chitosan, sulphated polysaccharides, and glycoconjugates. Their therapeutic actions are very broad since they comprise beneficial effects in many systems such as inflammation, coagulation, thrombosis, cancer growth/metastasis, and vascular biology. Additional information about the enzymatic synthesis, chemically modified derivatives, relevance of composing units, and other biochemical properties of these marine medicinal glycans are also discussed herein.



Marine Glycobiology Glycomics And Lectins


Marine Glycobiology Glycomics And Lectins
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Author : Yasuhiro Ozeki
language : en
Publisher:
Release Date : 2019

Marine Glycobiology Glycomics And Lectins written by Yasuhiro Ozeki and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Biochemistry categories.


Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”--that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences.This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined.



Marine Glycobiology


Marine Glycobiology
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Author : Se-Kwon Kim
language : en
Publisher: CRC Press
Release Date : 2016-10-14

Marine Glycobiology written by Se-Kwon Kim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-14 with Medical categories.


Marine glycobiology is an emerging and exciting area in the field of science and medicine. Glycobiology, the study of the structure and function of carbohydrates and carbohydrate-containing molecules, is fundamental to all biological systems and represents a developing field of science that has made huge advances in the last half-century. This book revolutionizes the concept of marine glycobiology, focusing on the latest principles and applications of marine glycobiology and their relationships.



Marine Omics


Marine Omics
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Author : Se-Kwon Kim
language : en
Publisher: CRC Press
Release Date : 2016-11-18

Marine Omics written by Se-Kwon Kim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-18 with Medical categories.


This book provides comprehensive coverage on current trends in marine omics of various relevant topics such as genomics, lipidomics, proteomics, foodomics, transcriptomics, metabolomics, nutrigenomics, pharmacogenomics and toxicogenomics as related to and applied to marine biotechnology, molecular biology, marine biology, marine microbiology, environmental biotechnology, environmental science, aquaculture, pharmaceutical science and bioprocess engineering.



Glycan Diversity In Fungi Bacteria And Sea Organisms


Glycan Diversity In Fungi Bacteria And Sea Organisms
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Author : Eliana Barreto-Bergter
language : en
Publisher: Frontiers Media SA
Release Date : 2016-09-07

Glycan Diversity In Fungi Bacteria And Sea Organisms written by Eliana Barreto-Bergter and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-07 with Infectious and parasitic diseases categories.


The cell surface of fungi, bacteria and sea organisms is highly glycosylated. These glycans are oligo- or polysaccharide molecules that can be secreted or attached to protein or lipids forming glycoconjugates. They present extraordinary structural diversity that could explain their involvement in many fundamental cellular processes, including growth, differentiation and morphogenesis. Considerable advances have been made on the structural elucidation of these glycans. Their primary structures were determined based on a combination of mass spectrometry and NMR spectroscopy techniques. The combination of these sensitive and powerful techniques has allowed us to increase our structural knowledge of a wide variety of glycans expressed by different fungi, bacteria and sea organisms.



Marine Glycosides


Marine Glycosides
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Author : Thomas E Adrian
language : en
Publisher: MDPI
Release Date : 2019-05-03

Marine Glycosides written by Thomas E Adrian and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-03 with Medical categories.


In recent years, there has been a steady increase in the publication of papers on the chemistry, biology, and potential clinical uses of marine glycosides. Indeed, more than half of the papers published in this field are less than a decade old. Glycosides have been isolated from species as diverse as algae, fungi, anthozoans, and echinoderms. Even fish of the genus Pardachirus produce glycosides, which they use as shark repellents.The major interest in these compounds as potential drugs stems from their broad spectrum of biological effects. They have been shown to have antimicrobial, antifungal, anti-inflammatory, immune modulatory, and anticancer effects. The anticancer effects of marine glycosides include cell cycle suppression, the induction of apoptosis, and the inhibition of migration, invasion, and metastasis, as well as antiangiogenesis. Marine glycosides influence membrane permeability and have been shown to influence membrane transport at the molecular level through effects on transport carriers and pumps, as well as effects on ligand-gated and voltage-gated channels. Various marine glycosides have been shown to activate sphingomyelinase and ceramide synthesis, to inhibit topoisomerase activity, receptor tyrosine kinase activity, and multidrug resistance protein activity, and to antagonize eicosanoid receptors.This Special Issue covers the entire scope of marine organism-derived glycosides that are of potential value as pharmaceutical agents or leads. These include, but are not limited to, tetracyclic triterpene glycosides, other triterpene glycosides, steroid glycosides, and glycosides of non-isoprenoid aglycones.



Marine Nutraceuticals


Marine Nutraceuticals
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Author : Se-Kwon Kim
language : en
Publisher: CRC Press
Release Date : 2013-03-25

Marine Nutraceuticals written by Se-Kwon Kim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-25 with Medical categories.


There is a great deal of consumer interest in natural bioactive substances due to their health benefits. Offering the potential to provide valuable nutraceuticals and functional food ingredients, marine-derived compounds are an abundant source of nutritionally and pharmacologically active agents, with both chemical diversity and complexity. Functio



Functional Glycomics


Functional Glycomics
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Author : Minoru Fukuda
language : en
Publisher: Elsevier
Release Date : 2006-12-08

Functional Glycomics written by Minoru Fukuda and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-08 with Science categories.


In the past decade, there has been an explosion of progress in understanding the roles of carbohydrates in biological systems. This explosive progress was made with the efforts in determining the roles of carbohydrates in immunology, neurobiology and many other disciplines, examining each unique system and employing new technology. This volume represents the second of three in the Methods in Enzymology series, including Glycobiology (vol. 415) and Glycomics (vol. 416), dedicated to disseminating information on methods in determining the biological roles of carbohydrates. These books are designed to provide an introduction of new methods to a large variety of readers who would like to participate in and contribute to the advancement of glycobiology. The methods covered include structural analysis of carbohydrates, biological and chemical synthesis of carbohydrates, expression and determination of ligands for carbohydrate-binding proteins, gene expression profiling including micro array, and generation of gene knockout mice and their phenotype analyses.