Mathematical Modeling Of Endocrine Systems

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Mathematical Modeling Of Endocrine Systems

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Author : Darko Stefanovski
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-04

Mathematical Modeling Of Endocrine Systems written by Darko Stefanovski and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-04 with Medical categories.

Mathematical Modelling And Computers In Endocrinology

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Author : Rosalind McIntosh
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Mathematical Modelling And Computers In Endocrinology written by Rosalind McIntosh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

The building of conceptual models is an inherent part of our interaction with the world, and the foundation of scientific investigation. Scientists often perform the processes of modelling subconsciously, unaware of the scope and significance of this activity, and the techniques available to assist in the description and testing of their ideas. Mathematics has three important contributions to make in biological modelling: (1) it provides unambiguous languages for expressing relationships at both qualitative and quantitative levels of observation; (2) it allows effective analysis and prediction of model behaviour, and can thereby organize experimental effort productively; (3) it offers rigorous methods of testing hypotheses by comparing models with experimental data; by providing a means of objectively excluding unsuitable concepts, the development of ideas is given a sound experimental basis. Many modern mathematical techniques can be exploited only with the aid of computers. These machines not only provide increased speed and accuracy in determining the consequences of model assumptions, but also greatly extend the range of problems which can be explored. The impact of computers in the biological sciences has been widespread and revolutionary, and will continue to be so.

Mathematical Modeling In Experimental Nutrition Vitamins Proteins Methods

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Author :
language : en
Publisher: Academic Press
Release Date : 1996-12-02

Mathematical Modeling In Experimental Nutrition Vitamins Proteins Methods written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-12-02 with Mathematics categories.

This book developed from a series of conferences to facilitate the application of mathematical modeling to experimental nutrition. As nutrition science moves from prevention of gross deficiencies to identifying requirements for optimum long term health, more sophisticated methods of nutritional assessment will be needed. Collection and evaluation of kinetic data may be one such method.This books opens with chapters giving specific examples of the application of modeling techniques to vitamin A, carotenoids, folate, vitamin b-6, glycogen phosphorylase, transthyretin, amino acids, and energy metabolism. Obtaining kinetic data on internal processes is a major challenge; therefore, the text includes chapters on the use of microdialysis and ultrafiltration, use of membrane vesicles, and culture of mammary tissue.Many of the authors use the Simulation, Analysis and Modeling program which allows compartmental models to be described without specifying the required differential equations. The final sections of the book, however, present some more mathematical descriptions of physiological processes, including bioperiodicity, metabolic control, and membrane transport; discussions of some computational aspects of modeling such as parameter distributions, linear integrators and identifiability; and alternative mathematical approaches such as neural networks and graph theory. - Specific, detailed examples of applications of modeling to vitamins, proteins, amino acids, and energy metabolism - Novel methods for collecting kinetic data--microdialysis, ultrafiltration, membrane vesicles, and the culture of mammary tissue - Mathematical treatment of complex metabolic processes including bioperiodicity, metabolic control, and membrane transport - Computational approaches to distribution of kinetic parameters, evaluation of linear integrators, and identifiability - Alternative mathematical approaches--neural networks and graph theory - Detailed descriptions of the application of modeling to a variety of nutrients

The Mathematical Modeling Of Metabolic And Endocrine Systems

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Author : Ewart R. Carson
language : en
Publisher:
Release Date :

The Mathematical Modeling Of Metabolic And Endocrine Systems written by Ewart R. Carson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.

Mathematical Modeling In Experimental Nutrition

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Author : Andrew J. Clifford
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21

Mathematical Modeling In Experimental Nutrition written by Andrew J. Clifford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Medical categories.

Nutrients have been recognized as essential for maximum growth, successful reproduction, and infection prevention since the 1940s; since that time, the lion's share of nutrient research has focused on defining their role in these processes. Around 1990, however, a major shift began in the way that researchers viewed some nutrients particularly the vitamins. This shift was motivated by the discovery that modest declines in vitamin nutritional status are associated with an increased risk of ill-health and disease (such as neural tube defects, heart disease, and cancer), especially in those populations or individuals who are genetically predisposed. In an effort to expand upon this new understanding of nutrient action, nutritionists are increasingly turning their focus to the mathematical modeling of nutrient kinetic data. The availability of suitably-tagged (isotope) nutrients (such as B-carotene, vitamin A, folate, among others), sensitive analytical methods to trace them in humans (mass spectrometry and accelerator mass spectrometry), and powerful software (capable of solving and manipulating differential equations efficiently and accurately), has allowed researchers to construct mathematical models aimed at characterizing the dynamic and kinetic behavior of key nutrients in vivo in humans at an unparalleled level of detail.

Mathematical Modeling In Nutrition And The Health Sciences

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Author : Janet A. Novotny
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Mathematical Modeling In Nutrition And The Health Sciences written by Janet A. Novotny and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Computers categories.

This volume is the proceedings of the 7th Mathematical Modeling in Experimental Nutrition Conference held at Penn State University July 29 until August 1, 2000. The book addresses the determination of optimal intakes of nutrients and food components to provide lifelong health and reduce incidence of disease. Mathematical modelling provides a means of rigorously defining the functions of a system and using a variety of conditions to stimulate responses. This volume presents the newest advances in modelling and related experimental techniques required to meet the new challenges currently facing nutrition and biological science.

Research Review

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Author :
language : en
Publisher:
Release Date : 1969-03

Research Review written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969-03 with Research categories.

Mathematical Physiology

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Author : James Keener
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-04

Mathematical Physiology written by James Keener and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-04 with Mathematics categories.

Divided into two volumes, the book begins with a pedagogical presentation of some of the basic theory, with chapters on biochemical reactions, diffusion, excitability, wave propagation and cellular homeostasis. The second, more extensive part discusses particular physiological systems, with chapters on calcium dynamics, bursting oscillations and secretion, cardiac cells, muscles, intercellular communication, the circulatory system, the immune system, wound healing, the respiratory system, the visual system, hormone physiology, renal physiology, digestion, the visual system and hearing. New chapters on Calcium Dynamics, Neuroendocrine Cells and Regulation of Cell Function have been included. Reviews from first edition: Keener and Sneyd's Mathematical Physiology is the first comprehensive text of its kind that deals exclusively with the interplay between mathematics and physiology. Writing a book like this is an audacious act! -Society of Mathematical Biology Keener and Sneyd's is unique in that it attempts to present one of the most important subfields of biology and medicine, physiology, in terms of mathematical "language", rather than organizing materials around mathematical methodology. -SIAM review

Research Review

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Author : United States. Air Force. Office of Aerospace Research
language : en
Publisher:
Release Date : 1969

Research Review written by United States. Air Force. Office of Aerospace Research and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with categories.

Dynamic Systems Biology Modeling And Simulation

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Author : Joseph DiStefano III
language : en
Publisher: Academic Press
Release Date : 2015-01-10

Dynamic Systems Biology Modeling And Simulation written by Joseph DiStefano III and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-10 with Science categories.

Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels. The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author's own modeling efforts, publications and teaching over half a century. Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical. The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility. The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications. - Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics - The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of "math modeling with life sciences - Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization - Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models - A full set of PowerPoint slides are available from the author for teaching from his textbook. He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course - Importantly, the slides are editable, so they can be readily adapted to a lecturer's personal style and course content needs. The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content - The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: [email protected]