Mathematics Of Dna Structure Function And Interactions


Mathematics Of Dna Structure Function And Interactions
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Mathematics Of Dna Structure Function And Interactions


Mathematics Of Dna Structure Function And Interactions
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Author : Craig John Benham
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-29

Mathematics Of Dna Structure Function And Interactions written by Craig John Benham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-29 with Medical categories.


Propelled by the success of the sequencing of the human and many related genomes, molecular and cellular biology has delivered significant scientific breakthroughs. Mathematics (broadly defined) continues to play a major role in this effort, helping to discover the secrets of life by working collaboratively with bench biologists, chemists and physicists. Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular Biology, held September 15--21 at the IMA. This volume is dedicated to the memory of Nicholas R. Cozzarelli, a dynamic leader who fostered research and training at the interface between mathematics and molecular biology. It contains a personal remembrance of Nick Cozzarelli, plus 15 papers contributed by workshop speakers. The papers give an overview of state-of-the-art mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes.



Dna Structure And Function


Dna Structure And Function
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Author : Richard R. Sinden
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Dna Structure And Function written by Richard R. Sinden and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


DNA Structure and Function, a timely and comprehensive resource, is intended for any student or scientist interested in DNA structure and its biological implications. The book provides a simple yet comprehensive introduction to nearly all aspects of DNA structure. It also explains current ideas on the biological significance of classic and alternative DNA conformations. Suitable for graduate courses on DNA structure and nucleic acids, the text is also excellent supplemental reading for courses in general biochemistry, molecular biology, and genetics. Explains basic DNA Structure and function clearly and simply Contains up-to-date coverage of cruciforms, Z-DNA, triplex DNA, and other DNA conformations Discusses DNA-protein interactions, chromosomal organization, and biological implications of structure Highlights key experiments and ideas within boxed sections Illustrated with 150 diagrams and figures that convey structural and experimental concepts



Dna Interactions With Drugs And Other Small Ligands


Dna Interactions With Drugs And Other Small Ligands
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Author : Marcio Santos Rocha
language : en
Publisher: Elsevier
Release Date : 2023-03-01

Dna Interactions With Drugs And Other Small Ligands written by Marcio Santos Rocha and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-01 with Medical categories.


DNA Interactions With Drugs and Other Small Ligands: Single Molecule Approaches and Techniques provides the reader with all the main information, a "state-of-the-art" of sorts and an overall review of the field. There is no other book currently available that covers all these subjects together. On the contrary, the different subjects that are developed in this book are currently scattered in journal articles and other books. Presents a review of the fundamental knowledge, techniques and relevant information surrounding the field of DNA interactions with drugs and other ligands Provides a resource like no other book available Includes valuable information from the author who is a highly experienced researcher in the field



Advanced Mechanical Models Of Dna Elasticity


Advanced Mechanical Models Of Dna Elasticity
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Author : Yakov M Tseytlin
language : en
Publisher: Academic Press
Release Date : 2016-07-29

Advanced Mechanical Models Of Dna Elasticity written by Yakov M Tseytlin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-29 with Science categories.


Advanced Mechanical Models of DNA Elasticity includes coverage on 17 different DNA models and the role of elasticity in biological functions with extensive references. The novel advanced helicoidal model described reflects the direct connection between the molecule helix structure and its specific properties, including nonlinear features and transitions. It provides an introduction to the state of the field of DNA mechanics, known and widely used models with their short analysis, as well as coverage on experimental methods and data, the influence of electrical, magnetic, ionic conditions on the persistence length, and dynamics with viscosity influence. It then addresses the need to understand the nature of the non-linear overstretching transition of DNA under force and why DNA has a negative twist-stretch coupling. Includes coverage of 17 contemporary models of DNA mechanics with analysis Provides comparison of DNA and RNA mechanical features Covers advances in experimental techniques including AFM, X-ray, and optical tweezers Contains extensive references for further reading



The Mathematical Nature Of The Living World


The Mathematical Nature Of The Living World
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Author : Gilbert Chauvet
language : en
Publisher: World Scientific
Release Date : 2005

The Mathematical Nature Of The Living World written by Gilbert Chauvet and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Mathematics categories.


The topic of the book a theory of functional biology thatincorporates the fundamental principles underlying the functioning ofliving organisms is clearly appropriate as we celebrate the 50thanniversary of the discovery by Watson and Crick of the structure ofthe DNA molecule.



Advances In The Mathematical Sciences


Advances In The Mathematical Sciences
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Author : Alyson Deines
language : en
Publisher: Springer
Release Date : 2018-10-31

Advances In The Mathematical Sciences written by Alyson Deines and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-31 with Mathematics categories.


Featuring research from the 2017 research symposium of the Association for Women in Mathematics, this volume presents recent findings in pure mathematics and a range of advances and novel applications in fields such as engineering, biology, and medicine. Featured topics include geometric group theory, generalized iterated wreath products of cyclic groups and symmetric groups, Conway-Coxeter friezes and mutation, and classroom experiments in teaching collegiate mathematics. A review of DNA topology and a computational study of learning-induced sequence reactivation during sharp-wave ripples are also included in this volume. Numerous illustrations and tables convey key results throughout the book. This volume highlights research from women working in academia, industry, and government. It is a helpful resource for researchers and graduate students interested in an overview of the latest research in mathematics.



Discrete And Topological Models In Molecular Biology


Discrete And Topological Models In Molecular Biology
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Author : Nataša Jonoska
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-23

Discrete And Topological Models In Molecular Biology written by Nataša Jonoska and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-23 with Computers categories.


Theoretical tools and insights from discrete mathematics, theoretical computer science, and topology now play essential roles in our understanding of vital biomolecular processes. The related methods are now employed in various fields of mathematical biology as instruments to "zoom in" on processes at a molecular level. This book contains expository chapters on how contemporary models from discrete mathematics – in domains such as algebra, combinatorics, and graph and knot theories – can provide perspective on biomolecular problems ranging from data analysis, molecular and gene arrangements and structures, and knotted DNA embeddings via spatial graph models to the dynamics and kinetics of molecular interactions. The contributing authors are among the leading scientists in this field and the book is a reference for researchers in mathematics and theoretical computer science who are engaged with modeling molecular and biological phenomena using discrete methods. It may also serve as a guide and supplement for graduate courses in mathematical biology or bioinformatics, introducing nontraditional aspects of mathematical biology.



Biophysics Of Dna Protein Interactions


Biophysics Of Dna Protein Interactions
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Author : Mark C. Williams
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-05

Biophysics Of Dna Protein Interactions written by Mark C. Williams and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-05 with Science categories.


Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating single molecule methods are beginning to appear. However, the promise of single molecule biophysics is to contribute to the understanding of specific fields of biology using new methods. This book would focus on the specific topic of the biophysics of DNA-protein interactions, and would include the use of new approaches, including both bulk methods as well as single molecule methods. This would make the book attractive to anyone working in the general area of DNA-protein interactions, which is of course a much wider market than just single molecule biophysicists or even biophysicists. The subject of the book will be the biophysics of DNA-protein interactions, and will include new methods and results that describe the physical mechanism by which proteins interact with DNA. For example, there has been much recent work on the mechanism by which proteins search for specific binding sites on DNA. A few chapters will be devoted to experiments and theory that shed light on this important problem. We will also cover proteins that alter DNA properties to facilitate interactions important for transcription or replication. Another section of the book will cover the biophysical mechanism by which motor proteins interact with DNA. Finally, we will cover larger protein-DNA complexes, such as replication forks, recombination complexes, DNA repair interactions, and their chromatin context.



Mathematical Analysis And Applications In Modeling


Mathematical Analysis And Applications In Modeling
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Author : Priti Kumar Roy
language : en
Publisher: Springer Nature
Release Date : 2020-03-10

Mathematical Analysis And Applications In Modeling written by Priti Kumar Roy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-10 with Mathematics categories.


This book collects select papers presented at the “International Conference on Mathematical Analysis and Application in Modeling,” held at Jadavpur University, Kolkata, India, on 9–12 January 2018. It discusses new results in cutting-edge areas of several branches of mathematics and applications, including analysis, topology, dynamical systems (nonlinear, topological), mathematical modeling, optimization and mathematical biology. The conference has emerged as a powerful forum, bringing together leading academics, industry experts and researchers, and offering them a venue to discuss, interact and collaborate in order to stimulate the advancement of mathematics and its industrial applications.



Mobile Dna Iii


Mobile Dna Iii
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Author : Michael Chandler
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-24

Mobile Dna Iii written by Michael Chandler and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-24 with Science categories.


An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.