Discrete And Topological Models In Molecular Biology
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Discrete And Topological Models In Molecular Biology
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Author : Nataša Jonoska
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-23
Discrete And Topological Models In Molecular Biology written by Nataša Jonoska and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-23 with Computers categories.
Theoretical tools and insights from discrete mathematics, theoretical computer science, and topology now play essential roles in our understanding of vital biomolecular processes. The related methods are now employed in various fields of mathematical biology as instruments to "zoom in" on processes at a molecular level. This book contains expository chapters on how contemporary models from discrete mathematics – in domains such as algebra, combinatorics, and graph and knot theories – can provide perspective on biomolecular problems ranging from data analysis, molecular and gene arrangements and structures, and knotted DNA embeddings via spatial graph models to the dynamics and kinetics of molecular interactions. The contributing authors are among the leading scientists in this field and the book is a reference for researchers in mathematics and theoretical computer science who are engaged with modeling molecular and biological phenomena using discrete methods. It may also serve as a guide and supplement for graduate courses in mathematical biology or bioinformatics, introducing nontraditional aspects of mathematical biology.
Mathematical Models In Biology
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Author : Elizabeth Spencer Allman
language : en
Publisher: Cambridge University Press
Release Date : 2004
Mathematical Models In Biology written by Elizabeth Spencer Allman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Mathematics categories.
This introductory textbook on mathematical biology focuses on discrete models across a variety of biological subdisciplines. Biological topics treated include linear and non-linear models of populations, Markov models of molecular evolution, phylogenetic tree construction, genetics, and infectious disease models. The coverage of models of molecular evolution and phylogenetic tree construction from DNA sequence data is unique among books at this level. Computer investigations with MATLAB are incorporated throughout, in both exercises and more extensive projects, to give readers hands-on experience with the mathematical models developed. MATLAB programs accompany the text. Mathematical tools, such as matrix algebra, eigenvector analysis, and basic probability, are motivated by biological models and given self-contained developments, so that mathematical prerequisites are minimal.
Topology In Molecular Biology
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Author : Michael I. Monastyrsky
language : en
Publisher: Springer
Release Date : 2006-10-23
Topology In Molecular Biology written by Michael I. Monastyrsky and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-23 with Science categories.
Computational Molecular Biology
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Author : S. Istrail
language : en
Publisher: Gulf Professional Publishing
Release Date : 2003-04-02
Computational Molecular Biology written by S. Istrail and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-04-02 with Computers categories.
This volume contains papers demonstrating the variety and richness of computational problems motivated by molecular biology. The application areas within biology that give rise to the problems studied in these papers include solid molecular modeling, sequence comparison, phylogeny, evolution, mapping, DNA chips, protein folding and 2D gel technology. The mathematical techniques used are algorithmics, combinatorics, optimization, probability, graph theory, complexity and applied mathematics. This is the fourth volume in the Discrete Applied Mathematics series on computational molecular biology, which is devoted to combinatorial and algorithmic techniques in computational molecular biology. This series publishes novel research results on the mathematical and algorithmic foundations of the inherently discrete aspects of computational biology. Key features: . protein folding . phylogenetic inference . 2-dimensional gel analysis . graphical models for sequencing by hybridisation . dynamic visualization of molecular surfaces . problems and algorithms in sequence alignment This book is a reprint of Discrete Applied Mathematics Volume 127, Number 1.
Algebraic And Discrete Mathematical Methods For Modern Biology
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Author : Raina Robeva
language : en
Publisher: Academic Press
Release Date : 2015-05-09
Algebraic And Discrete Mathematical Methods For Modern Biology written by Raina Robeva and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-09 with Mathematics categories.
Written by experts in both mathematics and biology, Algebraic and Discrete Mathematical Methods for Modern Biology offers a bridge between math and biology, providing a framework for simulating, analyzing, predicting, and modulating the behavior of complex biological systems. Each chapter begins with a question from modern biology, followed by the description of certain mathematical methods and theory appropriate in the search of answers. Every topic provides a fast-track pathway through the problem by presenting the biological foundation, covering the relevant mathematical theory, and highlighting connections between them. Many of the projects and exercises embedded in each chapter utilize specialized software, providing students with much-needed familiarity and experience with computing applications, critical components of the "modern biology" skill set. This book is appropriate for mathematics courses such as finite mathematics, discrete structures, linear algebra, abstract/modern algebra, graph theory, probability, bioinformatics, statistics, biostatistics, and modeling, as well as for biology courses such as genetics, cell and molecular biology, biochemistry, ecology, and evolution. Examines significant questions in modern biology and their mathematical treatments Presents important mathematical concepts and tools in the context of essential biology Features material of interest to students in both mathematics and biology Presents chapters in modular format so coverage need not follow the Table of Contents Introduces projects appropriate for undergraduate research Utilizes freely accessible software for visualization, simulation, and analysis in modern biology Requires no calculus as a prerequisite Provides a complete Solutions Manual Features a companion website with supplementary resources
Models And Modeling In The Sciences
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Author : Stephen M. Downes
language : en
Publisher: Routledge
Release Date : 2020-07-09
Models And Modeling In The Sciences written by Stephen M. Downes and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-09 with Philosophy categories.
Biologists, climate scientists, and economists all rely on models to move their work forward. In this book, Stephen M. Downes explores the use of models in these and other fields to introduce readers to the various philosophical issues that arise in scientific modeling. Readers learn that paying attention to models plays a crucial role in appraising scientific work. This book first presents a wide range of models from a number of different scientific disciplines. After assembling some illustrative examples, Downes demonstrates how models shed light on many perennial issues in philosophy of science and in philosophy in general. Reviewing the range of views on how models represent their targets introduces readers to the key issues in debates on representation, not only in science but in the arts as well. Also, standard epistemological questions are cast in new and interesting ways when readers confront the question, "What makes for a good (or bad) model?" All examples from the sciences and positions in the philosophy of science are presented in an accessible manner. The book is suitable for undergraduates with minimal experience in philosophy and an introductory undergraduate experience in science. Key features: The book serves as a highly accessible philosophical introduction to models and modeling in the sciences, presenting all philosophical and scientific issues in a nontechnical manner. Students and other readers learn to practice philosophy of science by starting with clear examples taken directly from the sciences. While not comprehensive, this book introduces the reader to a wide range of views on key issues in the philosophy of science.
Recombinatorics
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Author : Dan Gusfield
language : en
Publisher: MIT Press
Release Date : 2014-07-03
Recombinatorics written by Dan Gusfield and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-03 with Mathematics categories.
When a Philadelphia girl intercepts a message about an impending British attack against her father's regiment, commanded by General Washington, in White Marsh, she travels alone by horseback to warn the Patriot army.
Computational Systems Biology
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Author : Reinhard Laubenbacher
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-11-26
Computational Systems Biology written by Reinhard Laubenbacher and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-26 with Medical categories.
Mathematical and statistical network modeling is an important step toward uncovering the organizational principles and dynamic behavior of biological networks. This chapter focuses on methods to construct discrete dynamic models of gene regulatory networks from experimental data sets, also sometimes referred to as top-down modeling or reverse engineering. Time-discrete dynamical systems models have long been used in biology, particularly in population dynamics. The models mainly focused on here are also assumed to have a finite set of possible states for each variable. That is, the modeling framework discussed in this chapter is that of time-discrete dynamical systems over a finite state set.
Models And Algorithms For Biomolecules And Molecular Networks
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Author : Bhaskar DasGupta
language : en
Publisher: John Wiley & Sons
Release Date : 2016-01-26
Models And Algorithms For Biomolecules And Molecular Networks written by Bhaskar DasGupta and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-26 with Science categories.
By providing expositions to modeling principles, theories, computational solutions, and open problems, this reference presents a full scope on relevant biological phenomena, modeling frameworks, technical challenges, and algorithms. Up-to-date developments of structures of biomolecules, systems biology, advanced models, and algorithms Sampling techniques for estimating evolutionary rates and generating molecular structures Accurate computation of probability landscape of stochastic networks, solving discrete chemical master equations End-of-chapter exercises
Emerging Trends In Applications And Infrastructures For Computational Biology Bioinformatics And Systems Biology
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Author : Hamid R Arabnia
language : en
Publisher: Morgan Kaufmann
Release Date : 2016-03-25
Emerging Trends In Applications And Infrastructures For Computational Biology Bioinformatics And Systems Biology written by Hamid R Arabnia and has been published by Morgan Kaufmann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-25 with Computers categories.
Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research