The Topological Model Of Genome And Evolution

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The Topological Model Of Genome And Evolution
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Author : Pradeep Chhaya
language : en
Publisher: Springer Nature
Release Date : 2023-09-19
The Topological Model Of Genome And Evolution written by Pradeep Chhaya and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Science categories.
This book deals with the missing link in the domain of functional genomics viz. genomic architecture. It begins with a deconstruction of the Darwinian paradigm using the proposed model of modified involuted manifolds. It recasts the process of natural selection as a process of information transfer. Using a topological model, this book outlines a new genomic architecture. The key argument for this proposed model is that some such structuralism has always been implicit in genomics. The proposed model fits very well with the known genomic characteristics and allows to separate the regulatory genome from the transcriptive genomes. The model is capable of discerning modular architecture of genomes with different genomic functionalities existing in hierarchical relationships and demonstrates that genomes act as units of selection and as the environment for the individual genes which act as competing species. Towards the end, the book also examines the role of genomic evolution in cancer and the principles of natural selection and evolution of the genotype. The regulatory genome is also discussed, with an emphasis on its evolution and natural selection. It is a valuable source for researchers working in functional genomics, mathematical modeling in biology and evolutionary genomics.
Topological Data Analysis For Genomics And Evolution
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Author : Raul Rabadan
language : en
Publisher: Cambridge University Press
Release Date : 2019-12-19
Topological Data Analysis For Genomics And Evolution written by Raul Rabadan and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-19 with Mathematics categories.
An introduction to geometric and topological methods to analyze large scale biological data; includes statistics and genomic applications.
Mobile Elements And Plant Genome Evolution Comparative Analyses And Computational Tools Volume Ii
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Author : Ruslan Kalendar
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-28
Mobile Elements And Plant Genome Evolution Comparative Analyses And Computational Tools Volume Ii written by Ruslan Kalendar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-28 with Science categories.
This Research Topic is part of the Mobile Elements and Plant Genome Evolution, Comparative Analyses and Computational Tools series: Mobile Elements and Plant Genome Evolution, Comparative Analyses and Computational Tools Transposable elements are very common mobile genetic elements that are composed of several classes and make up the majority of eukaryotic genomes. The movement and accumulation of mobile genetic elements have been a major force in the formation of the genes and genomes of nearly all organisms. As dispersed and ubiquitous mobile elements, their life cycle of replicative transposition leads to genome rearrangements affecting cellular function. Transposable elements are important drivers of species diversity, and they exhibit great variety in structure, size, and mechanisms of transposition, making them important putative actors in genome evolution.
Genome Chaos
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Author : Henry H. Heng
language : en
Publisher: Academic Press
Release Date : 2019-05-25
Genome Chaos written by Henry H. Heng and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-25 with Medical categories.
Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine. - Bridges basic research and clinical application and provides a foundation for re-examining the results of large-scale omics studies and advancing molecular medicine - Gathers the most pressing questions in genomic and cytogenomic research - Offers alternative explanations to timely puzzles in the field - Contains eight evidence-based chapters that discuss 4d-genomics, genes and genomes as distinct biological entities, genome chaos and macro-cellular evolution, evolutionary cytogenetics and cancer, chromosomal coding and fuzzy inheritance, and more
Models And Algorithms For Genome Evolution
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Author : Cedric Chauve
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-09-17
Models And Algorithms For Genome Evolution written by Cedric Chauve and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-17 with Computers categories.
This authoritative text/reference presents a review of the history, current status, and potential future directions of computational biology in molecular evolution. Gathering together the unique insights of an international selection of prestigious researchers, this must-read volume examines the latest developments in the field, the challenges that remain, and the new avenues emerging from the growing influx of sequence data. These viewpoints build upon the pioneering work of David Sankoff, one of the founding fathers of computational biology, and mark the 50th anniversary of his first scientific article. The broad spectrum of rich contributions in this essential collection will appeal to all computer scientists, mathematicians and biologists involved in comparative genomics, phylogenetics and related areas.
Insights In Evolutionary Genomic Microbiology 2022
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Author : Ernesto Perez-Rueda
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-31
Insights In Evolutionary Genomic Microbiology 2022 written by Ernesto Perez-Rueda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-31 with Science categories.
This Research Topic is part of the Insights in Frontiers in Microbiology series. We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists in the field of Microbiology have been exceptional, leading to major advancements. Frontiers has organized a series of Research Topics to highlight the latest advancements in science in order to be at the forefront of science in different fields of research. This specific editorial initiative, led by Dr. Ernesto Perez-Rueda and Dr. Feng Gao, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances and future perspectives in the field.
Evolution Development And Ecology Of Anemonefishes
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Author : Vincent Laudet
language : en
Publisher: CRC Press
Release Date : 2022-11-07
Evolution Development And Ecology Of Anemonefishes written by Vincent Laudet and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-07 with Science categories.
Anemonefishes, one of the most popular and recognizable of fishes in the world, are much more than film characters; they are also emerging model organisms for studying the biology, ecology, and evolution of coral reef fishes. They are a group of 28 species often employed to study patterns and processes of social organization, intra- and inter-specific competition, sex change, mutualism, dispersal and connectivity of fish populations, habitat selection, pigment pattern formation, lifespan and predator-prey interactions. This multi-authored book covers all these areas and provides an update on the research done with this model and the perspective it opens for the future. Key Features Contains basic and up-to-date information on an emerging fish model Allows non-specialist readers to grasp the relevance of a wide research area Provides accurate and easy to access information on each of the 28 species Includes guidance for establishing a breeding colony Documents that anemonefishes are useful model organisms for ecological, developmental and climate research The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
Genomic Control Process
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Author : Isabelle S. Peter
language : en
Publisher: Academic Press
Release Date : 2015-01-21
Genomic Control Process written by Isabelle S. Peter and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-21 with Science categories.
Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. - Covers a vast area of current biological research to produce a genome oriented regulatory bioscience of animal life - Places gene regulation, embryonic and postembryonic development, and evolution of the body plan in a unified conceptual framework - Provides the conceptual keys to interpret a broad developmental and evolutionary landscape with precise experimental illustrations drawn from contemporary literature - Includes a range of material, from developmental phenomenology to quantitative and logic models, from phylogenetics to the molecular biology of gene regulation, from animal models of all kinds to evidence of every relevant type - Demonstrates the causal power of system-level understanding of genomic control process - Conceptually organizes a constellation of complex and diverse biological phenomena - Investigates fundamental developmental control system logic in diverse circumstances and expresses these in conceptual models - Explores mechanistic evolutionary processes, illuminating the evolutionary consequences of developmental control systems as they are encoded in the genome
Algorithms In Bioinformatics
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Author : Mihai Pop
language : en
Publisher: Springer
Release Date : 2015-08-27
Algorithms In Bioinformatics written by Mihai Pop and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-27 with Computers categories.
This book constitutes the refereed proceedings of the 15th International Workshop on Algorithms in Bioinformatics, WABI 2015, held in Atlanta, GA, USA, in September 2015. The 23 full papers presented were carefully reviewed and selected from 56 submissions. The selected papers cover a wide range of topics from networks to phylogenetic studies, sequence and genome analysis, comparative genomics, and RNA structure.
The Structure And Dynamics Of Networks
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Author : Mark Newman
language : en
Publisher: Princeton University Press
Release Date : 2011-10-23
The Structure And Dynamics Of Networks written by Mark Newman and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-23 with Mathematics categories.
From the Internet to networks of friendship, disease transmission, and even terrorism, the concept--and the reality--of networks has come to pervade modern society. But what exactly is a network? What different types of networks are there? Why are they interesting, and what can they tell us? In recent years, scientists from a range of fields--including mathematics, physics, computer science, sociology, and biology--have been pursuing these questions and building a new "science of networks." This book brings together for the first time a set of seminal articles representing research from across these disciplines. It is an ideal sourcebook for the key research in this fast-growing field. The book is organized into four sections, each preceded by an editors' introduction summarizing its contents and general theme. The first section sets the stage by discussing some of the historical antecedents of contemporary research in the area. From there the book moves to the empirical side of the science of networks before turning to the foundational modeling ideas that have been the focus of much subsequent activity. The book closes by taking the reader to the cutting edge of network science--the relationship between network structure and system dynamics. From network robustness to the spread of disease, this section offers a potpourri of topics on this rapidly expanding frontier of the new science.