Mechanical Engineering Of The Cytoskeleton In Developmental Biology
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Mechanical Engineering Of The Cytoskeleton In Developmental Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 1994-04-22
Mechanical Engineering Of The Cytoskeleton In Developmental Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-04-22 with Science categories.
Developing organisms are systems in which the geometry, dynamics, and boundary conditions are all changing in the course of morphogenesis. The morphogenesis of cells and organisms appear to be mediated in part by the mechanically active components of the cytoskeleton. Mechanical forces have long been considered secondary to the effects of molecular mechanisms in cell growth, differentiation, and development. This volume explores the role of mechanical forces in cell growth and development and demonstrates its importance. This volume will prove invaluable to all biologists interested in the fundamentals of mechanical forces in development, from the advanced to the graduate researcher.
The Hypertrophied Heart
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Author : Nobuakira Takeda
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Hypertrophied Heart written by Nobuakira Takeda and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Whenever the heart is challenged with an increased work load for a prolonged period, it responds by increasing its muscle mass--a phenomenon known as cardiac hypertrophy. Although cardiac hypertrophy is commonly seen under physiological conditions such as development and exercise, a wide variety of pathological situa tions such as hypertension (pressure overload), valvular defects (volume overload), myocardial infarction (muscle loss), and cardiomyopathy (muscle disease) are also known to result in cardiac hypertrophy. Various hormones such as catecholamines, thyroid hormones, angiotensin II, endothelin, and growth factors have also been shown to induce cardiac hypertrophy. Although the exact mechanisms underlying or pathological forrns of cardiac hypertrophy are poorly under the physiological stood, an increase in the intraventricular pressure is believed to represent the major stimulus for the development of cardiac hypertrophy. In this regard, stretching of the cardiac muscle has been shown to induce the hypertrophic response, but the role of metabolic influences in this process cannot be ruled out. Furthermore, different hormones and other interventions in the absence of stretch have been observed to stimulate protein synthesis in both isolated cardiomyocyte and vascular myocyte preparations. Nonetheless, it is becoming dear that receptor as well as phospholipid linked signal transduction pathways are activated in some specific manner depend ing upon the initial hypertrophic stimulus, and these then result in an increase in the size and mass of cardiomyocytes.
Regenerative Engineering And Developmental Biology
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Author : David M. Gardiner
language : en
Publisher: CRC Press
Release Date : 2017-08-21
Regenerative Engineering And Developmental Biology written by David M. Gardiner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-21 with Medical categories.
Regenerative Engineering and Developmental Biology: Principles and Applications examines cutting-edge developments in the field of regenerative engineering. Specific attention is given to activities that embrace the importance of integrating developmental biology and tissue engineering, and how this can move beyond repairing damage to body parts to instead regenerate tissues and organs. The text furthermore focusses on the five legs of the field of regenerative engineering, including: materials, developmental biology, stem cells, physics, and clinical translation. This book was written by leading developmental biologists; each chapter examines the processes that these biologists study and how they can be advanced by using the tools available in tissue engineering/biomaterials. Individual chapters are complete with concluding remarks and thoughts on the future of regenerative engineering. A list of references is also provided to aid the reader with further research. Ultimately, this book achieves two goals. The first encourages the biomedical community to think about how inducing regeneration is an engineering problem. The second goal highlights the discoveries with animal regeneration and how these processes can be engineered to regenerate body parts. Regenerative Engineering and Developmental Biology: Principles and Applications was written with undergraduate and graduate-level biomedical engineering students and biomedical professionals in mind.
Oh Omnivore The Path Of An Eclectic Theoretical Biologist
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Author : Richard Gordon
language : en
Publisher: World Scientific
Release Date : 2025-04-02
Oh Omnivore The Path Of An Eclectic Theoretical Biologist written by Richard Gordon and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-02 with Science categories.
Richard Gordon is a theoretical biologist who has led a multifaceted career, with research spanning various fields and being a professor in departments as varied as Radiology and Botany. His eclectic scientific pursuits and prolific writing have resulted in over 200 peer-reviewed publications, as well as many edited books and special issues.This is his personal memoir. It is based on a review of all his publications from Gordon's early years to the present. He recounts the collaborations, most importantly including the development of the nonlinear Algebraic Reconstruction Technique for image reconstruction, his most cited work. The ART algorithm today forms the basis of technologies that have dramatically improved progress from both basic science and in medicine such as computed tomography to 3D imaging of the sun's corona from satellites launched around the sun.The memoir offers a unique blend of scientific storytelling, personal reflection, and humanitarian endeavor, providing a fascinating glimpse into the life and work of a theoretical biologist with a remarkable range of interests and accomplishments. The overarching theme is how does one survive as a generalist in an academic world of specialists? The key seems to have been to have many collaborators, both in and outside the academic world, and diverse grant sources. The result has been an enjoyable and highly productive career, exploring many aspects of the world, from amusing games to profound scientific and philosophical questions, to potentially significant contributions to humanity. By following his interests, Gordon shows it is still possible to be a polymath in a fractionated world. Along the way, the author suggests many outstanding problems he's encountered that readers may want to tackle themselves.
Mechanical Engineering Of The Cytoskeleton In Developmental Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 1994-03-21
Mechanical Engineering Of The Cytoskeleton In Developmental Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-03-21 with Science categories.
Developing organisms are systems in which the geometry, dynamics, and boundary conditions are all changing in the course of morphogenesis. The morphogenesis of cells and organisms appear to be mediated in part by the mechanically active components of the cytoskeleton. Mechanical forces have long been considered secondary to the effects of molecular mechanisms in cell growth, differentiation, and development. This volume explores the role of mechanical forces in cell growth and development and demonstrates its importance. This volume will prove invaluable to all biologists interested in the fundamentals of mechanical forces in development, from the advanced to the graduate researcher.
Mechanics Of Motor Proteins And The Cytoskeleton
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Author : Jonathon Howard
language : en
Publisher: Sinauer
Release Date : 2005-12-06
Mechanics Of Motor Proteins And The Cytoskeleton written by Jonathon Howard and has been published by Sinauer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-06 with Science categories.
Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together.
Intelligent Surfaces In Biotechnology
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Author : H. Michelle Grandin
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-03
Intelligent Surfaces In Biotechnology written by H. Michelle Grandin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-03 with Technology & Engineering categories.
A comprehensive overview of smart and responsive surfaces in biotechnology and their applications A wave of recent advances in cell biology, biophysics, chemistry, and materials science has enabled the development of a new generation of smart biomaterials. Intelligent Surfaces in Biotechnology: Scientific and Engineering Concepts, Enabling Technologies, and Translation to Bio-Oriented Applications provides readers with a comprehensive overview of surface modifications and their applications, including coverage of the physico-chemical properties, characterization methods, smart coating technologies, and demonstration of performance in vitro and in vivo. The first part of the book covers applications in the fields of biosensing and biodiagnostics, while the second part focuses more on coatings for medical devices, drug delivery, and tailored cell-surface interactions. The book explores intelligent surface applications such as tissue engineering, drug targeting and delivery, wound healing and anti-infection strategies, biosensors, nanopatterning, and bioinspired design of novel responsive materials and multifunctional surfaces. Designed to aid scientists and engineers in understanding the rapidly developing field of biofunctional surfaces, Intelligent Surfaces in Biotechnology is an edited volume with each chapter written by a respected expert and featuring examples taken from the most state-of-the-art developments in the discipline. Cover Image: Design concept for a diagnostic microfluidic system based on responsive polymer- and antibody-conjugated nanobeads (see Chapter 2 of this book, Figure 2.5; reproduced by permission from the Royal Society of Chemistry).
Systems Biology Of Cancer
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Author : Sam Thiagalingam
language : en
Publisher: Cambridge University Press
Release Date : 2015-04-09
Systems Biology Of Cancer written by Sam Thiagalingam and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-09 with Mathematics categories.
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Hierarchical Genome And Differentiation Waves The Novel Unification Of Development Genetics And Evolution In 2 Volumes
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Author : Richard Gordon
language : en
Publisher: World Scientific
Release Date : 1999-07-12
Hierarchical Genome And Differentiation Waves The Novel Unification Of Development Genetics And Evolution In 2 Volumes written by Richard Gordon and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-07-12 with Science categories.
Over the past few decades numerous scientists have called for a unification of the fields of embryo development, genetics, and evolution. Each field has glaring holes in its ability to explain the fundamental phenomena of life. In this book, the author shows how the phenomenon of cell differentiation, considered in its temporal and spatial aspects during embryogenesis, provides a starting point for a unified theory of multicellular organisms (plants, fungi and animals), including their evolution and genetics. This unification is based on the recent discovery of differentiation waves by the author and his colleagues, described in the appendices, and illustrated by a flip movie prepared by a medical artist. To help the reader through the many fields covered, a glossary is included.This book will be of great value to the researcher and practicing doctors/scientists alike. The research students will receive an in-depth tutorial on the topics covered. The seasoned researcher will appreciate the applications and the gold mine of other possibilities for novel research topics.
Forces In Biology Cell And Developmental Mechanobiology And Its Implications In Disease Volume Ii
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Author : Selwin K. Wu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-05
Forces In Biology Cell And Developmental Mechanobiology And Its Implications In Disease Volume Ii written by Selwin K. Wu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-05 with Science categories.