Mechanisms And Mediators Of Neuropathic Pain
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Mechanisms And Mediators Of Neuropathic Pain
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Author : Annika B. Malmberg
language : en
Publisher: Springer
Release Date : 2012-12-06
Mechanisms And Mediators Of Neuropathic Pain written by Annika B. Malmberg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Numerous improvements in our understanding of the mechanisms that underlie neuropathic pain states have come from the development of animal models, most of which involve partial peripheral nerve injury. The animal models have shown that nerve injury initiates a cascade of events resulting in altered neurochemistry and molecular biology of the peripheral neurons, the dorsal root ganglion cell, and changes in neurotransmitter and receptor expression in the dorsal horn of the spinal cord. Moreover, nerve injury produces anatomical changes with functional consequences. This volume summarises the current understanding of the pathophysiological processes in the peripheral and central nervous system that contribute to the neuropathic pain. It provides a timely review of neuropathic pain mechanisms, written by experts in the field.
Neuropathic Pain
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Author : David M. Simpson
language : en
Publisher: Oxford University Press
Release Date : 2012-06-21
Neuropathic Pain written by David M. Simpson and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-21 with Medical categories.
The incidence of neuropathic pain continues to rise, yet it is an affliction often misdiagnosed or inadequately treated. Although in recent years considerable research has been dedicated to understanding its mechanisms, there have been few advances in treatment. The contributors to this book are internationally renowned leaders in the fields of peripheral neuropathy and neuropathic pain. They discuss clinical approaches to diagnosis and treatment of neuropathic pain, its underlying mechanisms, and strategies for prevention. In addition, chapters cover timely issues, including legal and ethical concerns surrounding pain treatment, the status of clinical trial methods, and educational efforts. Comprehensive yet concise, this book serves as a guide for diagnostic approaches and treatment of neuropathic pain for the student, resident, practicing physician, researcher, and specialist.
Mechanisms Of Vascular Disease
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Author : Robert Fitridge
language : en
Publisher: University of Adelaide Press
Release Date : 2011
Mechanisms Of Vascular Disease written by Robert Fitridge and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Neuropathic Pain
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Author : Cory Toth
language : en
Publisher: Cambridge University Press
Release Date : 2013-11-07
Neuropathic Pain written by Cory Toth and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-07 with Medical categories.
Central or peripheral neuropathic pain can be caused by a wide range of injuries, infections and diseases such as: spinal cord injury, multiple sclerosis, stroke, herpes zoster, diabetes and cancer. Many of these pain syndromes are difficult to treat, representing a challenge for many neurologists not routinely trained in pain management. Written by an international team of experts in the field, Neuropathic Pain: Causes, Management and Understanding gives readers an in-depth understanding of the multitude of conditions causing neuropathic pain. Epidemiology, clinical diagnosis, pathophysiology, outcome measurement and the best evidence-based management of individual and general neuropathic pain conditions are also described in depth. A unique chapter, written from a patient's viewpoint, gives new insight into how chronic neuropathic pain affects the lives of those patients with the condition. This book is essential reading for all pain specialists, neurologists, psychiatrists and anesthesiologists who wish to better understand their patients' neuropathic pain.
Pathological Pain
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2004-08-20
Pathological Pain written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-08-20 with Medical categories.
Brings together contributions from key investigators in the area of pathological pain. It covers the receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opoid systems in neuropathy and opoid tolerance, and plastic changes related to pathological pain.
Pain Modulation
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Author : Howard L. Fields
language : en
Publisher: Elsevier Publishing Company
Release Date : 1988-01-01
Pain Modulation written by Howard L. Fields and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-01-01 with Medical categories.
This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.
Cytokines And Pain
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Author : L.R. Watkins
language : en
Publisher: Springer
Release Date : 2013-03-08
Cytokines And Pain written by L.R. Watkins and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.
Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation has on pain modulation. The purpose of this book is to examine, for the first time, immune-to-brain communication from the viewpoint of its effect on pain processing. It is aimed both at the basic scientist and health care providers, in order to clarify the major role that substances released by immune cells play in pain modulation. This book contains chapters contributed by all of the major laboratories focused on understanding how cytokines modulate pain. These chapters provide a unique vantage point from which to examine this question, as the summarized work ranges from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans.
Acute Pain Management
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Author : Raymond S. Sinatra
language : en
Publisher: Cambridge University Press
Release Date : 2009-04-27
Acute Pain Management written by Raymond S. Sinatra and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-27 with Medical categories.
This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.
Neuropathic Pain
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Author : David Martin Simpson
language : en
Publisher:
Release Date : 2012
Neuropathic Pain written by David Martin Simpson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Neuralgia categories.
The incidence of neuropathic pain continues to rise, yet it is an affliction often misdiagnosed or inadequately treated. Although in recent years considerable research has been dedicated to understanding its mechanisms, there have been few advances in treatment. The contributors to this book are internationally renowned leaders in the fields of peripheral neuropathy and neuropathic pain. They discuss clinical approaches to diagnosis and treatment of neuropathic pain, its underlying mechanisms, and strategies for prevention. In addition, chapters cover timely issues, including legal and ethical.
Analgesia
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Author : Christoph Stein
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-26
Analgesia written by Christoph Stein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-26 with Medical categories.
This book presents the development and experimental validation of the structural test strategy called Oscillation-Based Test – OBT in short. The results presented here assert, not only from a theoretical point of view, but also based on a wide experimental support, that OBT is an efficient defect-oriented test solution, complementing the existing functional test techniques for mixed-signal circuits.