Mechanisms Of Environmental Mutagenesis Carcinogenesis


Mechanisms Of Environmental Mutagenesis Carcinogenesis
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Mechanisms Of Environmental Mutagenesis Carcinogenesis


Mechanisms Of Environmental Mutagenesis Carcinogenesis
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Author : A. Kappas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Mechanisms Of Environmental Mutagenesis Carcinogenesis written by A. Kappas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.



Environmental Mutagenesis Carcinogenesis And Plant Biology


Environmental Mutagenesis Carcinogenesis And Plant Biology
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Author : Edward J. Klekowski
language : en
Publisher: Greenwood
Release Date : 1982

Environmental Mutagenesis Carcinogenesis And Plant Biology written by Edward J. Klekowski and has been published by Greenwood this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.




Mechanism Of Environmental Carcinogenesis


Mechanism Of Environmental Carcinogenesis
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Author : J. Carl Barrett
language : en
Publisher: CRC-Press
Release Date : 1987-07-31

Mechanism Of Environmental Carcinogenesis written by J. Carl Barrett and has been published by CRC-Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-07-31 with Medical categories.




Progress In Environmental Mutagenesis


Progress In Environmental Mutagenesis
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Author : European Environmental Mutagen Society. Yugoslav Section
language : en
Publisher: North-Holland
Release Date : 1980

Progress In Environmental Mutagenesis written by European Environmental Mutagen Society. Yugoslav Section and has been published by North-Holland this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Science categories.


Comparative mutagenesis: chemical versus radiation; Molecular mechanisms of genetic changes; Experimental and epidemiological approach to mutagenesis and carcinogenesis.



Mutation And The Environment Basic Mechanisms


Mutation And The Environment Basic Mechanisms
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Author :
language : en
Publisher:
Release Date : 1990

Mutation And The Environment Basic Mechanisms written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Carcinogenesis categories.




Mutagenic Effects Of Environmental Contaminants


Mutagenic Effects Of Environmental Contaminants
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Author : H.E. Sutton
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Mutagenic Effects Of Environmental Contaminants written by H.E. Sutton and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Mutagenic Effects of Environmental Contaminants investigates the mutagenic consequences of environmental contaminants, such as pesticides, industrials, food additives, drugs, and biologicals, as well as the possible relationships between mutagenesis and carcinogenesis. It describes the monitoring of chemical mutagens in the environment and the ways that genetic mutations cause disease in humans. Organized into 14 chapters, this volume begins with an overview of the current burden of human genetic disease and the biochemical mechanisms of mutation. It then discusses practical and feasible methods that use a variety of organisms to screen potential mutagenic agents, increased mutation rates in human populations, mutagens that are currently used commercially, and the interrelationships between mutagenicity, carcinogenicity, and teratogenicity. The reader is also introduced to genetic toxicology, detection of chemically induced mutations in experimental animals, and chromosome and somatic mutations in humans. This book is a valuable resource for scientists, policymakers, and administrators of environmental programs.



Induced Mutagenesis


Induced Mutagenesis
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Author : Christopher W. Lawrence
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Induced Mutagenesis written by Christopher W. Lawrence and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


Concern is often expressed that our environment may include an increasingly large variety of mutagens, but the extent of the potential hazard they pose has yet to be fully evaluated. A variety of empirical procedures has been devised with which to estimate the mutagenic potency of suspect agents, and the relative merits of different tests are currently under debate. Although such tests are of great value, and are indeed indispensable, they are not, nevertheless, sufficient. In the long term, accurate estimation of hazard will also require a better understanding of the various mechanisms of mutagenesis, and in many instances these remain remarkably elusive. Our knowledge and appreciation of the problem has increased substantially over the last few years, but the precise way in which many mutagens cause mutations is not yet known. The aims of this conference were therefore two-fold. The first was to survey present information about mutagenic mechanisms, drawing together data from work with various experimental approaches and organisms, in order to discern the principles governing the action of different mutagens. The second was to examine the implications of such principles for the execution and evaluation of test procedures, and critically assess the research areas that need further attention in order to improve the interpretation of test results. Chris Lawrence v ACKNOWLEDGEMENT We gratefully acknowledge the support provided for this Conference by the U.,S. Department of Energy, The Foundation for Microbiology, Exxon Corporation and the University of Rochester.



Environmental Mutagenesis


Environmental Mutagenesis
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Author : Consultant Surgeon Robin Phillips, Esq
language : en
Publisher: Academic Press
Release Date : 1995-10

Environmental Mutagenesis written by Consultant Surgeon Robin Phillips, Esq and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-10 with categories.


Germ-line and somatic mutations are recognized as significant causes of human disease, and so the detection, identification and study of mutagens in the environment is of increasing mutagenesis.Environmental Mutagenesis describes our current knowledge of the molecular mechanisms of mutagenesis and assesses the role of mutagens in cancer and inherited disease. Full details are also provided on all the major in vivo and in vitro methods of mutagenecity testing, including recently developed methods such as fluorescence in situ hybridization (FISH), the use of genetically engineered cells, and transgene technology.This book presents a unique overview of the current status of mutagenecity research and genetics toxicology in the form of reviews by leading researchers in the field. It is essential reading for all with an interest in genetic toxicology and molecular carcinogenesis, including molecular geneticists, genetic counselors and clinicians.



Quantitative Relationship Between Mutagenic And Carcinogenic Potencies


Quantitative Relationship Between Mutagenic And Carcinogenic Potencies
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Author :
language : en
Publisher: National Academies Press
Release Date : 1983-01-01

Quantitative Relationship Between Mutagenic And Carcinogenic Potencies written by and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-01-01 with Nature categories.




Genetic Toxicology Of Environmental Chemicals Basic Principles And Mechanisms Of Action


Genetic Toxicology Of Environmental Chemicals Basic Principles And Mechanisms Of Action
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Author : Claes Ramel
language : en
Publisher:
Release Date : 1986

Genetic Toxicology Of Environmental Chemicals Basic Principles And Mechanisms Of Action written by Claes Ramel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.