Mechanisms Of Epigenetics And Genetics In Leukemogenesis
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Mechanisms Of Epigenetics And Genetics In Leukemogenesis
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Author : Yonghui Li
language : en
Publisher: Frontiers Media SA
Release Date : 2022-04-29
Mechanisms Of Epigenetics And Genetics In Leukemogenesis written by Yonghui Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-29 with Medical categories.
Epigenetic Biomarkers And Diagnostics
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Author : Jose Luis Garcia-Gimenez
language : en
Publisher: Academic Press
Release Date : 2015-12-07
Epigenetic Biomarkers And Diagnostics written by Jose Luis Garcia-Gimenez and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-07 with Science categories.
Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders. The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. - Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognostics - Describes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnostics - Discusses the advances in epigenomics technologies, including next-generation sequencing based tools and applications - Expounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseases - Includes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies
A Picture Of Australia S Children 2012
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Author : Australian Institute of Health and Welfare
language : en
Publisher: AIHW
Release Date : 2012
A Picture Of Australia S Children 2012 written by Australian Institute of Health and Welfare and has been published by AIHW this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Children categories.
This report provides updated data on how Australia's children are faring. Statistics are presented against key national indicators of child health, development and wellbeing, including the Children's Headline Indicators. Topics include mortality, disability, breastfeeding, dental health, physical activity, nutrition, early childhood education, transition to school, literacy and numeracy, social and emotional development, teenage births, birth weight, alcohol and tobacco use during pregnancy, family functioning, family economic situation, parental health, non-parental care, neighbourhood safety, social capital, injuries, bullying, child abuse, violence, crime, homelessness, immunisation and screening, child care, and child protection. Though Australian children are doing well in some areas, there is still room for improvement, especially for children from Aboriginal and Torres Strait Islander backgrounds or from socioeconomically disadvantaged areas.
Environmental Epigenetics
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Author : L. Joseph Su
language : en
Publisher: Springer
Release Date : 2015-05-18
Environmental Epigenetics written by L. Joseph Su and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-18 with Medical categories.
This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.
Cancer Epigenetics
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Author : Trygve Tollefsbol
language : en
Publisher: CRC Press
Release Date : 2008-09-19
Cancer Epigenetics written by Trygve Tollefsbol and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-19 with Medical categories.
During the past few decades, it has become increasingly apparent that heredity is not the sole determining factor in disease development, such as cancer. This landmark work covers a wide array of aspects in the relatively new area of epigenetics, ranging from its role in the basic mechanisms of tumorigenesis, to the newest epigenetic drugs being de
Epigenetics Methods
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Author : Trygve O. Tollefsbol
language : en
Publisher: Academic Press
Release Date : 2020-07-08
Epigenetics Methods written by Trygve O. Tollefsbol and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-08 with Medical categories.
In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools researchers might employ. Epigenetics Methods offers comprehensive instruction in methods, protocols, and experimental approaches applied in field of epigenetics. Here, across thirty-five chapters, specialists offer step-by-step overviews of methods used to study various epigenetic mechanisms, as employed in basic and translational research. Leading the reader from fundamental to more advanced methods, the book begins with thorough instruction in DNA methylation techniques and gene or locus-specific methylation analyses, followed by histone modification methods, chromatin evaluation, enzyme analyses of histone methylation, and studies of non-coding RNAs as epigenetic modulators. Recently developed techniques and technologies discussed include single-cell epigenomics, epigenetic editing, computational epigenetics, systems biology epigenetic methods, and forensic epigenetic approaches. Epigenetics methods currently in-development, and their implication for future research, are also considered in-depth. In addition, as with the wider life sciences, reproducibility across experiments, labs, and subdisciplines is a growing issue for epigenetics researchers. This volume provides consensus-driven methods instruction and overviews. Tollefsbol and contributing authors survey the range of existing methods; identify best practices, common themes, and challenges; and bring unity of approach to a diverse and ever-evolving field. - Includes contributions by leading international investigators involved in epigenetic research and clinical and therapeutic application - Integrates technology and translation with fundamental chapters on epigenetics methods, as well as chapters on more novel and advanced epigenetics methods - Written at verbal and technical levels that can be understood by scientists and students alike - Includes chapters on state-of-the-art techniques such as single-cell epigenomics, use of CRISPR/Cas9 for epigenetic editing, and epigenetics methods applied to forensics
Acute Myelogenous Leukemia
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Author : Lalitha Nagarajan
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-20
Acute Myelogenous Leukemia written by Lalitha Nagarajan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-20 with Medical categories.
Acute myelogenous leukemia (AML), is the most common form of leukemia in adults. AML is a deadly form of malignancy, the prognosis for which has not improved in the last two decades. More importantly, it is a malignancy that is seen in older adults, therefore the number of cases is likely to rise as the population ages. Over the past 15 years, genetic mechanisms underlying AML have begun to unfold. Additional research in this area has helped identify key components and characteristics. Consequently, targeted therapy of AML is receiving much attention. It is the hope of researchers that as with chronic myelogenous leukemia (CML), and the drug, Gleevec, a targeted therapy for AML will be discovered.
Epigenetics And Proteomics Of Leukemia
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Author : R ̄uta Navakauskien ̇e
language : en
Publisher: Springer Nature
Release Date : 2021-09-14
Epigenetics And Proteomics Of Leukemia written by R ̄uta Navakauskien ̇e and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-14 with Science categories.
This book reviews the current state of epigenetics and proteomics of leukemia and introduces the methods that are important to process and evaluate these factors in leukemia. In particular, epigenetic modifiers and their inhibitors in leukemia treatment as well as approaches to the epigenetic treatment of leukemia are covered. Various computational methods for proteome analysis are also described in detail, including 2DE fractionation and visualization, proteomic data processing, image acquisition and data anlaysis, and more. Protein localization in leukemia is also covered, in addition to the future of leukemia therapy. Epigenetics and Proteomics of Leukemia is an ideal book for advanced biomedical scientists and students, medical doctors and students, bioinformatics and health informatics researchers, computational biologists, structural biologists, systems biologists, and bioengineers.
Flow Cytometry Immunohistochemistry And Molecular Genetics For Hematologic Neoplasms
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Author : Tsieh Sun
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2012-01-19
Flow Cytometry Immunohistochemistry And Molecular Genetics For Hematologic Neoplasms written by Tsieh Sun and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-19 with Medical categories.
Immunophenotyping is the most powerful tool in the routine diagnosis of hematologic neoplasms. Immunohistochemical technique is used in histology labs for this purpose, while flow cytometry is used in clinical labs. Although separately these 2 techniques are very useful in detecting lymphomas and leukemias, the combination of both creates a very powerful and definitive diagnostic tool. The addition of molecular genetics to the book makes it an all-encompassing reference text.
Proceedings Of 2nd International Congress On Epigenetics Chromatin 2017
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Author : ConferenceSeries
language : en
Publisher: ConferenceSeries
Release Date :
Proceedings Of 2nd International Congress On Epigenetics Chromatin 2017 written by ConferenceSeries and has been published by ConferenceSeries this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
November 06-08, 2017 Frankfurt, Germany Key Topics : Epigenetics, Epigenomics, Immunogenetics, Translational Epigenetics, Neurodevelopmental Disorders, Bioinformatics Development in Epigenetics, Epigenetics and Environmental Origins of Cancer, Epigenetic Diseases – Clinical Applications, Pharmacogenomics & Personalized Medicine, Genetic Disorders, Current Case studies/ Discussions: Epigenetics, Cancer Epigenetics, Epigenetics Inheritance, Epigenetic Regulation, Epigenetics Mechanism, Epigenetics Psychology, Epigenetics Factors, Epigenetics Therapy, Clinical Epigenetics, Epigenetics Markers, Epigenetics Methylation, Epigenetics Silencing, Epigenetics Alteration, Neuronal Epigenetics, Epigenetics and Nutrition, Reproductive Epigenetics, Animal Epigenetics, Plant Epigenetics, Medical Epigenetics,