Mechanisms Of Excitation Contraction Coupling In Myocytes From Normal And Chronically Ischemic Pig Myocardium

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Mechanisms Of Excitation Contraction Coupling In Myocytes From Normal And Chronically Ischemic Pig Myocardium
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Author : Virginie Bito
language : en
Publisher: Leuven University Press
Release Date : 2004-09
Mechanisms Of Excitation Contraction Coupling In Myocytes From Normal And Chronically Ischemic Pig Myocardium written by Virginie Bito and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09 with Medical categories.
Mechanism And Role Of Cyclooxygenase 2 Up Regulation By Photodynamic Therapy
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Author : Nico Hendrickx
language : en
Publisher: Leuven University Press
Release Date : 2006
Mechanism And Role Of Cyclooxygenase 2 Up Regulation By Photodynamic Therapy written by Nico Hendrickx and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
Quantification Of Regional Myocardial Deformation Normal Characteristics And Clinical Use In Ischaemic Heart Disease
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Author : Lieven Herbots
language : en
Publisher: Leuven University Press
Release Date : 2006
Quantification Of Regional Myocardial Deformation Normal Characteristics And Clinical Use In Ischaemic Heart Disease written by Lieven Herbots and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Coronary heart disease categories.
Functional Anatomy Of Visual Processing In The Cerebral Cortex Of The Macaque
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Author : Koen Nelissen
language : en
Publisher: Leuven University Press
Release Date : 2006
Functional Anatomy Of Visual Processing In The Cerebral Cortex Of The Macaque written by Koen Nelissen and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
In this thesis, we examined the monkey cortical regions involved in processing of color, visual motion information, and the recognition of actions done by others. The aim was to gain better insight in the functional organization of the monkey visual cortex using in-house developed functional imaging techniques. Two different functional imaging techniques were used in these studies, the double-label deoxyglucose technique (DG) and functional magnetic resonance imaging (fMRI) in the awake monkey (Chapter 2). Both techniques allow to obtain an overview of stimulus-related neural activity throughout the whole brain, integrated over a limited amount of time. The results of the color experiments (Chapter 3) clearly showed that color related information is processed within a group of areas belonging to the ventral stream, which is involved in the perception of objects. Color-related metabolic activity was observed in visual areas V1, V2, V3, V4 and inferotemporal cortex (area TEO and TE). These findings set to rest the longstanding controversial claims that color would be processed almost selectively in one extrastriate visual area (V4) (Zeki SM, Brain Res 1973 53: 422-427). These results also show the usefulness of whole brain functional mapping techniques, as a complimentary approach to single cell measurements. In Chapter 4, we investigated which regions in the superior temporal sulcus (STS) of the monkey are involved in the analysis of motion. While the caudal part of the STS has been studied extensively, including area MT/V5 and MST, little is known about motion sensitivity in more anterior-ventral STS regions. Using fMRI, we were able to localize and delineate six different motion sensitive regions in the STS. One of these regions, that we termed 1st (lower superior temporal), had not been described so far. We were able to further characterize the six motion sensitive regions, using a wide variety of motion-sensitivity tests. The results of the latter tests suggested that motion related information might be processed along a second pathway within the STS, in addition to the MT-MST path (which is involved in the perception of heading). This second pathway, which includes the more rostral motion sensitive STS regions (FST, 1st and STPm) is possibly involved in the visual processing of biological movements (movements of animate objects) and actions. Finally, we investigated how and where in the monkey brain visual information about actions done is processed (Chapter 5 and 6). We found (Chapter 5) that, in agreement with earlier single unit results, the observation of grasping movements activates several regions in the premotor cortex of the monkey. Remarkable is that these premotor regions predominantly have a motor function, coding different types of higher order motor acts (for instance grasping of an object). These results are in agreement with earlier suggestions that we are able to understand actions done by others, because observation of a particular motor act activates our own motor representation of the same act. Furthermore, these studies suggested that within the frontal cortex of the monkey, there is a distinction between context-dependent (a person grasping) and more abstract (a hand grasping) action representations. In Chapter 6 we studied two other regions which are involved in the processing of visual information of actions done by others, the superior temporal sulcus (STS) and the parietal cortex. In the parietal cortex, we found a similar distinction between context-dependent and more abstract action representations as observed in prefrontal cortex. These results suggest that the parietal cortex is not only involved in the visual control of action planning, but also in the visual processing of actions performed by others. Based upon anatomical connections between the STS, parietal and frontal regions and motion-, form- and action-related functional properties of the former regions, we tentatively suggest how information about actions done by others might be sent from the STS to the frontal cortex along three different pathways. The latter working hypothesis will be tested in the future by additional fMRI control experiments and by combining fMRI, inactivation and microstimulation experiments while monkeys perform grasping tasks and/or view actions performed by others.
Characterization Of The Glypican Receptor Receptor Function
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Author : Bart De Cat
language : en
Publisher: Leuven University Press
Release Date : 2004-09
Characterization Of The Glypican Receptor Receptor Function written by Bart De Cat and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09 with Science categories.
Genetic Modulators Of Pulmonary Function In Cystic Fibrosis And Genetic Susceptibility Factors Of Emphysema
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Author : Jennifer S. Yarden
language : en
Publisher: Leuven University Press
Release Date : 2005
Genetic Modulators Of Pulmonary Function In Cystic Fibrosis And Genetic Susceptibility Factors Of Emphysema written by Jennifer S. Yarden and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Cardioselective Nitric Oxide Synthase Gene Transfer To Target Myocardial Ischemia
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Author : Zsolt Szelid
language : en
Publisher: Leuven University Press
Release Date : 2005
Cardioselective Nitric Oxide Synthase Gene Transfer To Target Myocardial Ischemia written by Zsolt Szelid and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
This is a Ph.D. dissertation. Introduction: Cardiovascular and myocardial gene transfer, Gene delivery strategies to the cardiovascular system, Gene vector design, Adenovirus-mediated immunity and cardiovascular gene transfer, Myocardial gene transfer to target myocardial ischemia - reperfusion injury; Specific aims; Materials and methods: Construction of recombinant virus, Myocardial transfer and anti-adenoviral immunity, Gene transfer and myocardial ischemia-reperfusion injury, Statistical analysis; Results: Anti-adenoviral immunity and myocardial adenoviral gene transfer, Gene transfer and myocardial ischemia-reperfusion injury; Discussion: Pre-existing anti-adenoviral immunity and adenovirus-mediated myocardial gene transfer, Intramyocardial NOS3 gene transfer and adenovirus-mediated immune responses, Cardioselective NOS3 gene transfer and myocardial protection from reperfusion injury; General conclusions.
Rearrangement Of Ewsr1 And Taf15 With The Transcription Factor Ciz Nmp4 In Two Novel Recurrent Translocations T 12 17 P13 Q11 And T 12 22 P13 Q12 In Acute Leukemia
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Author : Alessandra Martini
language : en
Publisher: Leuven University Press
Release Date : 2004-09
Rearrangement Of Ewsr1 And Taf15 With The Transcription Factor Ciz Nmp4 In Two Novel Recurrent Translocations T 12 17 P13 Q11 And T 12 22 P13 Q12 In Acute Leukemia written by Alessandra Martini and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09 with Medical categories.
Complex Motion Processing In The Human Cerebral Cortex As Studied By Functional Imaging
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Author : Hendrik Peuskens
language : en
Publisher: Leuven University Press
Release Date : 2004-09
Complex Motion Processing In The Human Cerebral Cortex As Studied By Functional Imaging written by Hendrik Peuskens and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09 with Medical categories.
Physiological Study Of Presenilins And Baces Two Proteases Involved In The Pathogenesis Of Alzheimer S Disease
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Author : Jos Tournoy
language : en
Publisher: Leuven University Press
Release Date : 2006
Physiological Study Of Presenilins And Baces Two Proteases Involved In The Pathogenesis Of Alzheimer S Disease written by Jos Tournoy and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.