Mechanobiology Of Cell Cell And Cell Matrix Interactions

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Mechanobiology Of Cell Cell And Cell Matrix Interactions

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Author : A. Wagoner Johnson
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-02-21

Mechanobiology Of Cell Cell And Cell Matrix Interactions written by A. Wagoner Johnson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-21 with Technology & Engineering categories.

Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.

Mechanobiology In Health And Disease

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Author : Stefaan Verbruggen
language : en
Publisher: Academic Press
Release Date : 2018-08-24

Mechanobiology In Health And Disease written by Stefaan Verbruggen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-24 with Technology & Engineering categories.

Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology.

Biological Soft Matter

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Author : Corinne Nardin
language : en
Publisher: John Wiley & Sons
Release Date : 2021-06-28

Biological Soft Matter written by Corinne Nardin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-28 with Technology & Engineering categories.

Biological Soft Matter Explore a comprehensive, one-stop reference on biological soft matter written and edited by leading voices in the field Biological Soft Matter: Fundamentals, Properties and Applications delivers a unique and indispensable compilation of up-to-date knowledge and material on biological soft matter. The book presents a thorough overview about biological soft matter, beginning with different substance classes, including proteins, nucleic acids, lipids, and polysaccharides. It goes on to describe a variety of superstructures and aggregated and how they are formed by self-assembly processes like protein folding or crystallization. The distinguished editors have included materials with a special emphasis on macromolecular assembly, including how it applies to lipid membranes, and proteins fibrillization. Biological Soft Matter is a crucial resource for anyone working in the field, compiling information about all important substance classes and their respective roles in forming superstructures. The book is ideal for beginners and experts alike and makes the perfect guide for chemists, physicists, and life scientists with an interest in the area. Readers will also benefit from the inclusion of: An introduction to DNA nano-engineering and DNA-driven nanoparticle assembly Explorations of polysaccharides and glycoproteins, engineered biopolymers, and engineered hydrogels Discussions of macromolecular assemblies, including liquid membranes and small molecule inhibitors for amyloid aggregation A treatment of inorganic nanomaterials as promoters and inhibitors of amyloid fibril formation An examination of a wide variety of natural and artificial polymers Perfect for materials scientists, biochemists, polymer chemists, and protein chemists, Biological Soft Matter: Fundamentals, Properties and Applications will also earn a place in the libraries of biophysicists and physical chemists seeking a one-stop reference summarizing the rapidly evolving topic of biological soft matter.

Biomaterial Based Approaches To Study The Tumour Microenvironment

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Author : Jessica O Winter
language : en
Publisher: Royal Society of Chemistry
Release Date : 2022-12-07

Biomaterial Based Approaches To Study The Tumour Microenvironment written by Jessica O Winter and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-07 with Technology & Engineering categories.

The tumour microenvironment is increasingly recognized as an important contributor to cancer progression and treatment. However, most cancer studies continue to be performed in 2D tissue culture dishes that do not capture the characteristics of the tumour niche. This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies, including scaffold design and synthesis, chemical signalling and delivery, and co-culture, microfluidics, and organ-on-a-chip tools that can be used to mimic tumour microenvironment features. This book also includes discussion of emerging imaging methods compatible with tumour microenvironment mimicking biomaterials and discusses applications of such models in immuno-oncology, metastasis, and drug screening. Edited by two leaders in the field, this book will appeal to graduate students and researchers working in biomaterials science, chemical and biomedical engineering departments.

Comprehensive Biophysics

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Author :
language : en
Publisher: Academic Press
Release Date : 2012-04-12

Comprehensive Biophysics written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-12 with Science categories.

Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource

Mechanobiology Handbook Second Edition

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Author : Jiro Nagatomi
language : en
Publisher: CRC Press
Release Date : 2018-12-07

Mechanobiology Handbook Second Edition written by Jiro Nagatomi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-07 with Medical categories.

Mechanobiology—the study of the effects of mechanics on biological events—has evolved to answer numerous research questions. Mechanobiology Handbook 2nd Edition is a reference book for engineers, scientists, and clinicians who are interested in mechanobiology and a textbook for senior undergraduate to graduate level students of this growing field. Readers will gain a comprehensive review of recent research findings as well as elementary chapters on solid mechanics, fluid mechanics, and molecular analysis techniques. The new edition presents, in addition to the chapters of the first edition, homework problem sets that are available online and reviews of research in uncovered areas. Moreover, the new edition includes chapters on statistical analysis, design of experiments and optical imaging. The editors of this book are researchers and educators in mechanobiology. They realized a need for a single volume to assist course instructors as a guide for didactic teaching of mechanobiology to a diverse student body. A mechanobiology course is frequently made up of both undergraduate and graduate students pursuing degrees in engineering, biology, or integrated engineering and biology. Their goal was to present both the elementary and cutting-edge aspects of mechanobiology in a manner that is accessible to students from many different academic levels and from various disciplinary backgrounds. Moreover, it is their hope that the readers of Mechanobiology Handbook 2nd Edition will find study questions at the end of each chapter useful for long-term learning and further discussion. Comprehensive collection of reviews of recent research Introductory materials in mechanics, biology, and statistics Discussion of pioneering and emerging mechanobiology concepts Presentation of cutting-edge mechanobiology research findings across various fields and organ systems End of chapter study questions, available online Considering the complexity of the mechanics and the biology of the human body, most of the world of mechanobiology remains to be studied. Since the field is still developing, the Mechanobiology Handbook raises many different viewpoints and approaches with the intention of stimulating further research endeavours.

Principles Of Human Organs On Chips

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Author : Masoud Mozafari
language : en
Publisher: Woodhead Publishing
Release Date : 2023-01-17

Principles Of Human Organs On Chips written by Masoud Mozafari and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-17 with Technology & Engineering categories.

Principles of Human Organs-on-Chips covers all aspects of microfluidic organ-on-a-chip systems, from fabrication to application and commercialization. Organ-on-a-chip models are created to mimic the structural, microenvironmental and physiological functions of human organs, providing the potential to bypass some cell and animal testing methods. This is a useful platform with widespread applications, frequently in drug screening and pathological studies. This book offers a comprehensive and authoritative reference on microfluidic organs-on-chips, spanning all key aspects from fabrication methods, cell culture systems and cell-based analysis, to dedicated chapters on specific tissue types and their associated organ-on-a-chip models, as well as their use as disease models, drug screening platforms and more. Principles of Human Organs-on-Chips helps materials scientists and biomedical engineers to better understand the specific requirements and challenges in the design and fabrication of organ-on-a-chip devices. This book also bridges the knowledge gap between medical device design and subsequent clinical applications, allowing medical professionals to easily learn about related engineering concepts and techniques. - Describes various microfluidic systems and fabrication methods - Covers models and applications for a broad range of tissue types, including liver, eye, immune, gut, and more - Offers an interdisciplinary approach, combining engineering techniques and clinical applications of organs-on-chips

Extracellular Matrix For Tissue Engineering And Biomaterials

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Author : Anna C. Berardi
language : en
Publisher: Springer
Release Date : 2018-04-13

Extracellular Matrix For Tissue Engineering And Biomaterials written by Anna C. Berardi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-13 with Science categories.

This volume provides a state-of-art-report on the new methodologies in tissue engineering and developments in the biomaterials field based on the extracellular matrix-relevant discovery. Extracellular Matrix for Tissue Engineering and Biomaterials opens with an overview of the latest extracellular matrix research and in Part I, focuses on its biology and its role on cell behavior and cell fate relevant for the design of biomimetic surfaces. Part II details issues regarding the strategies currently applied in the research of biologically inspired materials and material systems for the replacement, repair and regeneration of tissues and organs. Part III presents the latest development methods applying knowledge from biology towards nanotechnology, to promote the restoration of the functionality of a living tissue. The book ranges from fundamental biology associated with tissue regeneration for the development of biomimetic approaches to controlling tissue formation, cell function, differentiation and angiogenesis using factors involved in normal tissue development and function. With the breadth and depth of the coverage of this topic, this book will serve as a valuable reference for anyone working in tissue engineering or biomaterials – from scientists, chemists and biologists through physicists, bioengineers and clinicians.

Basic Orthopaedic Biomechanics Mechano Biology

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Author : Van C. Mow
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2005

Basic Orthopaedic Biomechanics Mechano Biology written by Van C. Mow and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.

Biomaterials / Ahmed El-Ghannam and Paul Ducheyne -- Biomechanics of the spine / Ian A. F. Stokes and James C. Iatridis -- Biomechanics of fracture fixation and fracture healing / Lutz E. Claes and Keita Ito -- Biomechanics and preclinical testing of artificial joints: the hip / Rik Huiskes and Jan Stolk -- Biomechanics of total knee replacement designs / Peter S. Walker.

Natural And Synthetic Hydrogels

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Author : Ravin Narain
language : en
Publisher: Elsevier
Release Date : 2024-11-11

Natural And Synthetic Hydrogels written by Ravin Narain and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-11 with Science categories.

Natural and Synthetic Hydrogels: Rational Design, Synthesis and Biomedical Applications provides acomprehensive text on hydrogels and their biomedical uses, covering both fundamental and applied aspects of hydrogels. Hydrogels are three-dimensional network of cross-linked polymers or particles that contain a large amount of water. They have received tremendous attention for applications in biomedicines, which has led to significant progress in the design and engineering of the hydrogels to meet the needs for such applications.The book covers the recent developments that have been made in this field, including new applications of hydrogels, providing a new and fresh overview of hydrogels and their applications.Natural and Synthetic Hydrogels: Rational Design, Synthesis and Biomedical Applications is valuableto upper level undergraduate and graduate students, researchers, and progressors teaching fundamental and applied aspects of hydrogels. • Provides a complete description for design approaches, synthetic strategies, and their characterizations• Covers responsive hydrogels from the synthesis and application point-of-view• Evaluates modern techniques to prepare hydrogels and their characterizations