Membrane Microdomain Signaling
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Membrane Microdomain Signaling
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Author : Mark P. Mattson
language : en
Publisher: Springer Science & Business Media
Release Date : 2005
Membrane Microdomain Signaling written by Mark P. Mattson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
From intramolecular asymmetries to raft assemblies: a short guide for the puzzled in lipidomics / Ephraim Yavin and Annette Brand -- Regulatory aspects of membrane microdomain (raft) dynamics in live cells: a biophysical approach / János Matkó and János Szöllosi -- Lipid raft membrane skeletons / Elizabeth J. Luna ... [et al.] -- Role of cholesterol in membrane microdomain signaling / Christopher J. Fielding -- Raft lipid metabolism in relation to alkyl-lysophospholipid-induced apoptosis / Arnold H. van der Luit, Marcel Verheij, and Wim J. van Blitterswijk -- Role of lipid rafts in signal transduction and synaptic plasticity of neural cells / Markus Delling and Melitta Schachner -- Role of rafts in virus fusion and budding / Wu Ou and Jonathan Silver -- Alterations in raft lipid metabolism in aging and neurodegenerative disorders / Mark P. Mattson, Roy G. Cutler, and Norman J. Haughey -- Caveolin and cancer: a complex relationship / Mordechai Liscovitch ... [et al.] -- Dietary modulation of lipid rafts: implications for disease prevention and treatment / Mark P. Mattson.
Membrane Microdomain Regulation Of Neuron Signaling
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Author : Dr. Ron Wallace
language : en
Publisher:
Release Date : 2008
Membrane Microdomain Regulation Of Neuron Signaling written by Dr. Ron Wallace and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
The rapid pace of discovery in membrane molecular biology is revealing unexpected complexity at the boundary of the cell. The membrane appears to be more than a thin film separating aqueous compartments or an anchoring site for proteins. Indeed, it shows many indications of being a dynamic, regulatory structure composed of transient lipid ensembles known as rafts or microdomains. These appear to regulate the membrane-protein kinetics which is the basis of many cellular functions. This book describes those regulatory features in detail and presents evidence that they operate in the neuron.
Membrane Microdomain Regulation Of Neuron Signaling
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Author : Ron Wallace
language : en
Publisher: Nova Biomedical Books
Release Date : 2008
Membrane Microdomain Regulation Of Neuron Signaling written by Ron Wallace and has been published by Nova Biomedical Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Cell membranes categories.
Microdomains In The Cardiovascular System
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Author : Viacheslav Nikolaev
language : en
Publisher: Springer
Release Date : 2017-09-19
Microdomains In The Cardiovascular System written by Viacheslav Nikolaev and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-19 with Medical categories.
The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.
Membrane Dynamics And Domains
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Author : Peter J. Quinn
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Membrane Dynamics And Domains written by Peter J. Quinn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The fluid-mosaic model of membrane structure formulated by Singer and Nicolson in the early 1970s has proven to be a durable concept in terms of the principles governing the organization of the constituent lipids and proteins. During the past 30 or so years a great deal of information has accumulated on the composition of various cell membranes and how this is related to the dif ferent functions that membranes perform. Nevertheless, the task of explaining particular functions at the molecular level has been hampered by lack of struc tural detail at the atomic level. The reason for this is primarily the difficulty of crystallizing membrane proteins which require strategies that differ from those used to crystallize soluble proteins. The unique exception is bacteriorhodopsin of the purple membrane of Halobacterium halobium which is interpolated into a membrane that is neither fluid nor in a mosaic configuration. To date only 50 or so membrane proteins have been characterised to atomic resolution by diffraction methods, in contrast to the vast data accumulated on soluble proteins. Another factor that has been difficult to explain is the reason why the lipid compliment of membranes is often extremely complex. Many hundreds of different molecular species of lipid can be identified in some membranes. Remarkably, the particular composition of each membrane appears to be main tained within relatively narrow limits and its identity distinguished from other morphologically-distinct membranes.
Cell Membrane Nanodomains
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Author : Alessandra Cambi
language : en
Publisher: CRC Press
Release Date : 2014-10-27
Cell Membrane Nanodomains written by Alessandra Cambi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-27 with Medical categories.
Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field, the book explores areas where the application of these novel
Molecular Organization Of Membranes Where Biology Meets Biophysics
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Author : Marek Cebecauer
language : en
Publisher: Frontiers Media SA
Release Date : 2018-02-07
Molecular Organization Of Membranes Where Biology Meets Biophysics written by Marek Cebecauer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-07 with categories.
Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, regulate the function of all associated molecules. Therefore, studying interactions of components, biophysical properties and overall membrane dynamics provides essential information on its function in the context of cell activities. Such knowledge can contribute to biomedical fields such as pharmacology, immunology, neurobiology and many others. The goal of the Research Topic entitled ‘Molecular organisation of membranes: where biology meets biophysics’ was to provide a comprehensive platform for publishing articles, reviews and opinions focused on membrane organisation and the forces behind its heterogeneous and dynamic structure. We collected 11 works which cover topics as diverse as general membrane organisation models, membrane trafficking and signalling regulation, biogenesis of caveolae, protein-lipid interactions and the importance of membrane-associated tetraspanins networks. The prevalent theme was the existence of membrane nanodomains. To this point, new emerging technologies are presented which own the power to bring a novel insight on how membrane nanodomains are formed and maintained and what is their function. We believe that the collection of works in this Research Topic brings forward some important questions which will stimulate further research in this difficult but exciting field.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Membrane Microdomain Signaling
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Author : Mark P. Mattson
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-27
Membrane Microdomain Signaling written by Mark P. Mattson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-27 with Science categories.
Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the nervous system, and shows how alterations in lipid raft metabolism are implicated in the pathogenesis of neurodegenerative disorders. Techniques are also described for the isolation of lipid rafts, the analysis of the lipid and protein components of lipid rafts, the imaging of lipid rafts in living cells, and the analysis of signal transduction in lipid rafts.
Lipid Rafts And Caveolae
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Author : Christopher J. Fielding
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-13
Lipid Rafts And Caveolae written by Christopher J. Fielding and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Science categories.
This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include: Historical background Distinct structures and functions Structural basis Signaling Viral entry and virion budding Cholesterol transport Caveolins Lipid shells Cell polarity and intracellular trafficking Cancer cells Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.