Membrane Transport


Membrane Transport
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Membrane Transport


Membrane Transport
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Author : Daniel C. Tosteson
language : en
Publisher: Springer
Release Date : 2013-05-27

Membrane Transport written by Daniel C. Tosteson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-27 with Medical categories.


This is a fascinating collection of personal accounts which is a "must read" for anyone interested in membrane transport or the history of the development of the current picture of membrane transport physiology. This delightful book could serve variously as a history for investigators and historians or as a textbook for advanced students. No biology or medical library should be without it



Membrane Transport


Membrane Transport
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Author : Stephen A. Baldwin
language : en
Publisher: OUP Oxford
Release Date : 2000-06-15

Membrane Transport written by Stephen A. Baldwin and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06-15 with Science categories.


Membrane Transport is targeted towards researchers with an interest in the mechanism of solute transport across biological membranes. Its scope is broad, ranging from the techniques required to study transport itself, through the expression, purification and reconstitution of transporters, to techniques for investigation of their structures. As such, it not only proves the necessary technical grounding for newcomers to the field, but should also be of value to "old-hands" wishing to get up to date with recent developments in these areas. While some of the approaches described require sophisticated equipment (e.g. a stopped-flow fluorimeter), most of the protocols can be implemented in any well- found laboratory. Preparation of this volume comes at a time when a result of genome sequencing our knowledge of membrane transporter sequences is far outstripping our understanding of their molecular mechanisms. Our hope is that this book will help future researchers to redress this imbalance.



Cell Membrane Transport


Cell Membrane Transport
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Author : Arnost Kotyk
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Cell Membrane Transport written by Arnost Kotyk and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


TO THE SECOND EDITION When preparing the manuscript for the original edition of this book we were only partly aware of the pace at which the field of membrane transport was developing and at which new ideas as well as new techniques would be applied to it. The fact is that some of the chapters are now outdated (e. g. , the one on the molecular aspects of transport) and many others require revision in the light of new information that has appeared in the past five years. However, it is also true that we overemphasized in the first edition certain points that now appear less important and underestimated the impact of certain others that have since assumed a position among the most forcefully discussed topics of membrane research. In making amends, it was thus thought useful to include the discussion of these latter problems both in the theoretical and in the comparative sections and, on the other hand, to omit some of the less topical subjects. There was a different reason for rewriting the section on kidney and for dropping the section on mito chondria. The help of an expert nephrologist was enlisted for improving chapter 24, while it was decided that mitochondria represent a special field both conceptually (being only subcellular particles) and methodologically (more indirect estimation techniques being involved than with whole cells or tissues) and that more adequate information can be found in treatises specializing in work with mitochondria.



Membrane Transport


Membrane Transport
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Author : Arnost Kotyk
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Membrane Transport written by Arnost Kotyk and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Not many years ago, problems of membranes and transport attracted the attention of but a few dozen enthusiasts, mainly physiolo gists who recognize~ the significance of membranes for the stabilization of the general steady state of organisms. The first symposium organ ized some fifteen years ago could boast of the attendance of perhaps fifty scientists (the remaining fifty were not yet sure that membranes was the topic of their choice), ranging in specialization from physical chemistry to bacterial genetics, who clairvoyantly decided to study what now has become the number one subject at most congresses of biophysics, physiology, and even biochemistry and microbiology. As is the case with many rapidly developing fields, the interest in membranes and transport seems to be growing out of bounds and the whole field of membra no logy, interdisciplinary as it is, has penetrated into the realms of a number of branches of physics, chemistry, and biology. Its subject is primarily biological and, although much has been done in the world to increase the "exactness" of biology over the past thirty years, one cannot strive for a rigorous mathematical description of biological phenomena since, as M. H.



Channels Carriers And Pumps


Channels Carriers And Pumps
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Author : Wilfred D. Stein
language : en
Publisher: Elsevier
Release Date : 2014-12-09

Channels Carriers And Pumps written by Wilfred D. Stein and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-09 with Science categories.


An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building



Membrane Transport In Plants


Membrane Transport In Plants
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Author : U. Zimmermann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Membrane Transport In Plants written by U. Zimmermann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


In February, 1974, an 'International Workshop on Membrane Transport in Plants' was held at the Nuclear Research Centre, JLiI ich, West Germany. More than two hundred and fifty people, from fourteen countries, took part in this highly successful meeting. A somewhat similar meeting took place in Liverpool, England, two years ago and it became clear there that progress in the field of membrane transport in plants was now so marked that a second, and wider, meeting in Germany was more than fully justified. The members of our pro gramme committee (U. Zimmermann, Chairman, JLilich (FRG); J. Dainty,



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.




Membrane Transport Mechanism


Membrane Transport Mechanism
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Author : Reinhard Krämer
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-13

Membrane Transport Mechanism written by Reinhard Krämer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-13 with Science categories.


This book provides a molecular view of membrane transport by means of numerous biochemical and biophysical techniques. The rapidly growing numbers of atomic structures of transporters in different conformations and the constant progress in bioinformatics have recently added deeper insights. The unifying mechanism of energized solute transport across membranes is assumed to consist of the conformational cycling of a carrier protein to provide access to substrate binding sites from either side of a cellular membrane. Due to the central role of active membrane transport there is considerable interest in deciphering the principles of one of the most fundamental processes in nature: the alternating access mechanism. This book brings together particularly significant structure-function studies on a variety of carrier systems from different transporter families: Glutamate symporters, LeuT-like fold transporters, MFS transporters and SMR (RND) exporters, as well as ABC-type importers. The selected examples impressively demonstrate how the combination of functional analysis, crystallography, investigation of dynamics and computational studies has made it possible to create a conclusive picture or more precisely, “a molecular movie”. Although we are still far from a complete molecular description of the alternating access mechanism, remarkable progress has been made from static snapshots towards membrane transport dynamics.



Molecular Biology Of Membrane Transport Disorders


Molecular Biology Of Membrane Transport Disorders
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Author : Thomas E. Andreoli
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Molecular Biology Of Membrane Transport Disorders written by Thomas E. Andreoli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.


When the six of us gathered to start planning for what was to be the Third Edition of Physiology of Membrane Disorders, it was clear that since 1986, when the Second Edition appeared, the field had experienced the dawning of a new era dominated by a change in focus from phenomenology to underlying mechanisms propelled by the power of molecular biology. In 1985, detailed molecular information was available for only three membrane transporters: the lac permease, bacterial rhodopsin, and the acetylcholine receptor. During the decade that has since elapsed, almost all of the major ion channels and transport proteins have been cloned, sequenced, mutagenized, and expressed in homologous as well as heterologous cells. Few, if any, of the transporters that were identified during the previous era have escaped the probings of the new molecular technologies and, in many instances, considerable insight has been gained into their mechanisms of function in health and disease. Indeed, in some instances novel, unexpected transporters have emerged that have yet to have their functions identified. The decision to adopt the new title Molecular Biology of Membrane Transport Disorders was a natural outgrowth of these considerations.



Transport Across Multi Membrane Systems


Transport Across Multi Membrane Systems
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Author : G. Giebisch
language : en
Publisher: Springer
Release Date : 1978-12-01

Transport Across Multi Membrane Systems written by G. Giebisch and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978-12-01 with Medical categories.


The contributions of this volume are concerned with transport phenomena in multimembrane systems and in simple epithelia. In addition to the very substan tial progress that has been made in the area of transport of fluid and solutes across artifical model membranes in vitro and across simple symmetrical cell membranes, much has been learned from studies of transport phenomena in multi membrane systems of higher complexity to be reviewed in this volume. It should be recalled that many of the fundamental conceptual and methodological problems of transport physiology have been successfully approached and defin ed by studying simple epithelia in vitro, and that the direction that research has taken has been affected in a major way by the cellular transport models that have evolved from this approach. Since then striking progress has been made in several areas. Not only have we been witnessing a keen and productive interest in the realtionship between fine structure and transport behavior in multimem brane systems but significant advancements have also been made in defining individual active and passive transport operations, in analysing cell ion activities and transport pools, and in describing the differences in transport functions that underly the membrane asymmetry and cell polarization of cells subserving di rectional transport.