Metabolic Engineering For Bioprocess Commercialization

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Metabolic Engineering For Bioprocess Commercialization
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Author : Stephen Van Dien
language : en
Publisher: Springer
Release Date : 2016-07-16
Metabolic Engineering For Bioprocess Commercialization written by Stephen Van Dien and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-16 with Science categories.
This volume reviews the current metabolic engineering tools and technologies from a practical point of view, and guides researchers as they overcome challenges at various stages of organism and bioprocess development. Microbes have been engineered to produce a variety of industrial products such as fuels, basic chemicals, fine chemicals, nutritional supplements, and pharmaceutical intermediates, and new tools such as gene synthesis, advanced cloning techniques, ‘omics’ analysis, and mathematical modeling have greatly accelerated the pace of innovation in the field. Written by leading experts in the field from both academia and industry, key topics include synthetic biology, pathway engineering, metabolic flux manipulation, adaptive evolution, and fermentation process scale-up. It is suitable for non-specialists, and is a valuable resource for anyone embarking on the exciting path to harnessing the metabolic potential of microorganisms.
Introduction To Metabolic Engineering And Application
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Author : Dibyajit Lahiri
language : en
Publisher: Springer Nature
Release Date : 2025-07-26
Introduction To Metabolic Engineering And Application written by Dibyajit Lahiri and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-26 with Science categories.
The book unlocks the future of metabolic research with our comprehensive resource, designed for scientists, clinicians, and industry professionals. This expertly curated collection delves into cutting-edge advancements in metabolic pathways, disease mechanisms, and innovative therapeutic strategies. Covering everything from fundamental biochemistry to translational medicine, our content bridges the gap between research and clinical application. Whether you're exploring metabolic disorders, precision medicine, or novel biomarkers, this resource provides in-depth insights backed by the latest scientific discoveries. Elevate your expertise and stay ahead in the dynamic field of metabolic sciences—your essential guide to ground breaking innovations awaits.
Metabolic Pathway Design
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Author : Pablo Carbonell
language : en
Publisher: Springer Nature
Release Date : 2019-11-05
Metabolic Pathway Design written by Pablo Carbonell and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-05 with Medical categories.
This textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master’s students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.
Advanced Bioprocessing For Alternative Fuels Biobased Chemicals And Bioproducts
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Author : Majid Hosseini
language : en
Publisher: Woodhead Publishing
Release Date : 2019-02-28
Advanced Bioprocessing For Alternative Fuels Biobased Chemicals And Bioproducts written by Majid Hosseini and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-28 with Science categories.
Advanced Bioprocessing for Alternative Fuels, Bio-based Chemicals, and Bioproducts: Technologies and Approaches for Scale-Up and Commercialization demonstrates novel systems that apply advanced bioprocessing technologies to produce biofuels, bio-based chemicals, and value-added bioproducts from renewable sources. The book presents the use of novel oleaginous microorganisms and utilization strategies for applications of advanced bioprocessing technology in biofuels production and thoroughly depicts the technological breakthroughs of value added bioproducts. It also aides in the design, evaluation and production of biofuels by describing metabolic engineering and genetic manipulation of biofuels feedstocks. Users will find a thorough overview of the most recent discoveries in biofuels research and the inherent challenges associated with scale up. Emphasis is placed on technological milestones and breakthroughs in applications of new bioprocessing technologies for biofuels production. Its essential information can be used to understand how to incorporate advanced bioprocessing technologies into the scaling up of laboratory technologies to industrial applications while complying with biofuels policies and regulations.
Biomass Biofuels Biochemicals
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Author : Parameswaran Binod
language : en
Publisher: Elsevier
Release Date : 2021-06-03
Biomass Biofuels Biochemicals written by Parameswaran Binod and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-03 with Technology & Engineering categories.
Biodegradable Polymers and Composites - Process Engineering to Commercialization is designed in such a way that it not only gives basic knowledge but also contains information regarding conventional and advanced technologies, socio-economic aspects, techno-economic feasibility, modelling tools and detailed Life Cycle Analysis in biopolymer production. The book discusses the advantages and importance of biopolymers over the conventionally produced plastics. Biodegradable Polymers and Composites highlights: the conventional and advanced strategies for biopolymer production; information regarding process engineering and commercialization of biopolymers; models and available modelling techniques in the sector of biopolymer production; and global case studies, opportunities and challenges (technical constraints, institutional constraints and social constraints) associated with biopolymer production. - Outlines appropriate technologies for biopolymer production - Evaluates Best Available Technologies (BAT) and provides examples from many geographic areas - Offers tools enabling evaluation of appropriate technological systems to develop technically best and economical feasible polymers - Reports new research findings related to biopolymer production
Engineering Of Microbial Biosynthetic Pathways
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Author : Vijai Singh
language : en
Publisher: Springer Nature
Release Date : 2020-07-16
Engineering Of Microbial Biosynthetic Pathways written by Vijai Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-16 with Medical categories.
This book provides a comprehensive overview of the basic and advanced metabolic engineering technologies used to generate natural metabolites and industrially important biomolecules. Metabolic engineering has the potential to produce large quantities of valuable biomolecules in a renewable and sustainable manner by extending or modifying biosynthetic pathways in a wide range of organisms. It has been successfully used to produce chemicals, drugs, enzymes, amino acids, antibiotics, biofuels, and industrially important pharmaceuticals. The book comprehensively reviews the various metabolites detection, extraction and biosensors and the metabolic engineering of microbial strains for the production of industrially useful enzymes, proteins, organic acids, vitamins and antibiotics, therapeutics, chemicals, and biofuels. It also discusses various genetic engineering and synthetic biology tools for metabolic engineering. In closing, the book discusses ethical, patenting and regulatory issues in the metabolic engineering of microbes. This book is a valuable source not only for beginners in metabolic engineering, but also students, researchers, biotechnology and metabolic engineering based company.
Microbial Bioreactors For Industrial Molecules
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Author : Sudhir Pratap Singh
language : en
Publisher: John Wiley & Sons
Release Date : 2023-06-07
Microbial Bioreactors For Industrial Molecules written by Sudhir Pratap Singh and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-07 with Science categories.
Microbial Bioreactors for Industrial Molecules Harness the planet’s most numerous resources with this comprehensive guide Microorganisms constitute the invisible majority of all living creatures on Earth. They are found virtually everywhere on the planet, including in environments too extreme for any larger organisms to exist. They form a hugely significant resource whose potential value for human society cannot be overlooked. The creation of microorganism- based bioreactors for the industrial production of valuable biomolecules has the potential to revolutionize a range of industries and fields. Microbial Bioreactors for Industrial Molecules provides a comprehensive introduction to these bioresources. It covers all potential approaches to the use of microbial technology and the production of high-value biomolecules for the pharmaceutical, cosmetic, and agricultural industries, among others. The book’s rigorous detail and global, holistic approach to harnessing the power of the planetary microbiome make it an invaluable introduction to this growing area of research and production. Readers will also find: Detailed coverage of basic, applied, biosynthetic, and translational approaches to the use of microbial technology Discussion of industrially produced microbe-borne enzymes including invertase, lipase, keratinase, protease, and more Approaches for using microbial bioreactors to generate biofuels Microbial Bioreactors for Industrial Molecules is essential for scientists and researchers in microbiology and biotechnology, as well as for professionals in the biotech industries and graduate students studying the applications of the life sciences.
Microbial Products For Future Industrialization
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Author : Angana Sarkar
language : en
Publisher: Springer Nature
Release Date : 2023-10-11
Microbial Products For Future Industrialization written by Angana Sarkar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-11 with Science categories.
This book “Microbial Products for Future Industrialization” focuses on the exploitation of various advanced microbial and molecular biology technologies and their associated processes, especially the microbial-molecular-chemical nexus, for the future industrialization of emerging new microbial products. The descriptions given in its chapters take the reader through an entire journey of new emerging microbial products from lab to industry and provide new information that has not yet been fully exploited for future industrialization steps. This volume is a great resource for readers seeking a more comprehensive material covering the technical, economic, and societal aspects that impact bioprocessing of microbial products at the industrial level along with biotechnological intervention for better production of microbial products in near future. This book also encompasses advanced and updated information as well as future directions for young researchers and scientists, and academics who are working in the field of microbial product production related to sustainability.
Industrialization Of Biology
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2015-06-29
Industrialization Of Biology written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-29 with Science categories.
The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.
Biosurfactants Greener Surface Active Agents For Sustainable Future
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Author : Deepansh Sharma
language : en
Publisher: Springer Nature
Release Date : 2021-09-30
Biosurfactants Greener Surface Active Agents For Sustainable Future written by Deepansh Sharma and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-30 with Medical categories.
This book illustrates the importance and significance of the biosurfactants obtained from microorganisms, preferably from bacteria and yeast. It explains the superiority of biosurfactants (green molecule) over chemically synthesized surfactants for the sustainable future. The content of the present book addresses the quest for novel biosurfactants producing strains, high throughput screening methods, and production strategies. It finely describes the aptness of biosurfactants for industrial and environmental applications. It elaborately describes the technical background and cutting-edge advancement of the commercial aspect of biosurfactants. In the later part of the book, the role of green biosurfactants in food processing, control of food spoilage, incorporation in personal health care products, environmental and agricultural remediation are discussed. Finally, the book elucidates a comprehensive and representative description of toxicity assessment of the biosurfactants, which highlights the risk assessment of the incorporation of the microbial biosurfactants in food, healthcare, and pharmaceutical formulations.