Metabolic Engineering Of The Valine Pathway In Corynebacterium Glutamicum Analysis And Modelling
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Metabolic Engineering Of The Valine Pathway In Corynebacterium Glutamicum Analysis And Modelling
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Author : Jørgen Barsett Magnus
language : en
Publisher: Forschungszentrum Jülich
Release Date : 2007
Metabolic Engineering Of The Valine Pathway In Corynebacterium Glutamicum Analysis And Modelling written by Jørgen Barsett Magnus and has been published by Forschungszentrum Jülich this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Corynebacterium Glutamicum
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Author : Nami Tatsumi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-08-14
Corynebacterium Glutamicum written by Nami Tatsumi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-14 with Science categories.
Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
Microorganism And Process Engineering For Biosynthesis
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Author : Qi Xianghui
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-27
Microorganism And Process Engineering For Biosynthesis written by Qi Xianghui and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-27 with Science categories.
Systems Metabolic Engineering
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Author : Christoph Wittmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-15
Systems Metabolic Engineering written by Christoph Wittmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-15 with Science categories.
Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.
Metabolic Engineering
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Author : Sang Yup Lee
language : en
Publisher: CRC Press
Release Date : 1999-09-29
Metabolic Engineering written by Sang Yup Lee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-29 with Science categories.
This unique reference/text presents the basic theory and practical applications of metabolic engineering (ME). It offers systematic analysis of complex metabolic pathways and ways of employing recombinant DNA techniques to alter cell behavior, metabolic patterns, and product formation. Treating ME as a distinct subfield of genetic engineering, the book demonstrates new means of enabling cells to produce valuable proteins, polypeptides, and primary and secondary metabolites. Written by more than 35 leading international experts in the field, this book discusses metabolic engineering in plant and mammalian cells, bacteria, and yeasts and assesses metabolic engineering applications in agriculture, pharmaceuticals, and environmental systems. It illuminates the potential of the "cell factory" model for production of chemicals and therapeutics and examines methods for developing new antiviral and antibacterial molecules and effective gene and somatic-cell therapies. Metabolic Engineering also addresses the use of metabolic flux analysis, metabolic control analysis, and online metabolic flux analysis.
Corynebacterium Glutamicum
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Author : Masayuki Inui
language : en
Publisher: Springer Nature
Release Date : 2020-04-13
Corynebacterium Glutamicum written by Masayuki Inui and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-13 with Science categories.
This updated second edition covers the molecular biology, genome engineering tools and comprehensive analysis techniques for Corynebacterium glutamicum. Aside from modern omics-based approaches, the authors also focus on cell physiology, including cell division, central carbon metabolic pathways, and the respiratory chain. Readers will learn how primary mechanisms like energy metabolism can be applied in processes like biorefinery. Newly added topics include cell envelope structures and aromatic compound metabolism in C. glutamicum. These chapters will be particularly useful for those interested in the microbial production of commodity chemicals, fuels, and proteins. Corynebacteriacea are already some of the most important industrial microorganisms. Understanding the cell physiology of C. glutamicum will help manufacturers to increase their product range and productivity through efficient metabolic engineering.
The Handbook Of Microbial Metabolism Of Amino Acids
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Author : J P F D'Mello
language : en
Publisher: CABI
Release Date : 2017-04-10
The Handbook Of Microbial Metabolism Of Amino Acids written by J P F D'Mello and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-10 with Science categories.
This book collates and reviews recent advances in the microbial metabolism of amino acids, emphasizing diversity - in terms of the range of organisms under investigation and their natural ecology - and the unique features of amino acid metabolism in bacteria, yeasts, fungi, protozoa and nematodes. As well as studying the individual amino acids, including arginine, sulfur amino acids, branched-chain amino acids and aromatic amino acids, a number of themes are explored throughout the work. As the volume of research into the metabolism of amino acids grows, this comprehensive study of the subject is a vital tool for researchers in the fields of biological, medical and veterinary sciences, including microbiology, biochemistry, genetics and pathology. This book is also essential for corporate organizations with active research and development programmes, such as those in the pharmaceutical industry.
The Metabolic Pathway Engineering Handbook
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Author : Christina Smolke
language : en
Publisher: CRC Press
Release Date : 2009-07-28
The Metabolic Pathway Engineering Handbook written by Christina Smolke and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-28 with Medical categories.
This second volume of the Metabolic Pathway Engineering Handbook delves into evolutionary tools and gene expression tools for metabolic pathway engineering. It covers applications of emerging technologies including recent research genome-wide technologies, DNA and phenotypic microarrays, and proteomics tools for experimentally determining flux thro
The Metabolic Pathway Engineering Handbook Two Volume Set
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Author : Christina Smolke
language : en
Publisher: CRC Press
Release Date : 2009-08-18
The Metabolic Pathway Engineering Handbook Two Volume Set written by Christina Smolke and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-18 with Medical categories.
Christina Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer's yeast, is regarded as one of the most brilliant minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metab
Reprogramming Microbial Metabolic Pathways
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Author : Xiaoyuan Wang
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-20
Reprogramming Microbial Metabolic Pathways written by Xiaoyuan Wang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-20 with Computers categories.
Metabolic engineering has been developed over the past 20 years to become an important tool for rational engineering of microorganisms. This book has a particular interest in the methods and applications of metabolic engineering to improve the production and yield of a variety of metabolites in microorganisms. The overall goal is to achieve a better understanding of metabolism in different microorganisms, and provide a rational basis to reprogram microorganisms for improved biochemical production. This book brings together contributions from leading researchers at the cutting edge of these topics. The subject matter is divided into two sections. The first section deals with novel and emerging methods for redesigning microorganisms exploiting systems biology and gene regulation. The second discusses practical aspects of metabolic engineering for over production of a variety of valuable chemicals and materials by fermentation.