Metabolic Profiling
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Metabolic Profiling
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Author : Thomas O. Metz
language : en
Publisher: Humana Press
Release Date : 2011-04-06
Metabolic Profiling written by Thomas O. Metz and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-06 with Science categories.
At the intersection of metabolite analysis, metabolic fingerprinting, and metabolomics, the study of metabolic profiling has evolved steadily over the course of time as have the methods and technologies involved in its study. In Metabolic Profiling: Methods and Protocols, expert researchers in the field present protocols that are illustrative of the evolution of metabolic profiling from single molecule analysis to global metabolome profiling. Comprised of the most essential techniques, this volume covers topics from inborn errors of metabolism and drug metabolite analysis to nuclear magnetic resonance metabolic profiles. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Metabolic Profiling: Methods and Protocols serves as a resource for both established and new investigators in this vital and ever-developing field.
Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis
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Author : George G. Harrigan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis written by George G. Harrigan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.
Global Metabolic Profiling Clinical Applications
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Author : Georgios Theodoridis
language : en
Publisher:
Release Date : 2014
Global Metabolic Profiling Clinical Applications written by Georgios Theodoridis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Electronic books categories.
Metabolic Profiling
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Author : Martin Grootveld
language : en
Publisher: Royal Society of Chemistry
Release Date : 2014
Metabolic Profiling written by Martin Grootveld and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Science categories.
An exemplary new book on applications of metabolomic profiling techniques in the areas of drug therapy and toxicology, cancer, obesity, diabetes and cardiovascular, infectious, inflammatory, and oral diseases.
Metabolic Phenotyping In Personalized And Public Healthcare
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Author : Jeremy Nicholson
language : en
Publisher: Academic Press
Release Date : 2016-02-11
Metabolic Phenotyping In Personalized And Public Healthcare written by Jeremy Nicholson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-11 with Science categories.
Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches.In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics. In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream. Translates the conjunction of new surgical tools for intraoperative, real-time, metabolite evaluation and direct analysis of biofluid samples into novel options for augmented clinical decision-making Discusses longitudinal sampling from individual patients for stratified medicine Covers high resolution analytical spectroscopy and sophisticated computational modelling for prediction of adverse reactions in critical care scenarios, prognostic evaluation of cancer from biofluidism, and prognostic prediction of metabolism or response of patients to pharmaceutical interventions Encapsulates recent technology options for broader population profiling considerations, in particular, the metabolome-wide association studies (MWAS) that aid the translational researcher in identifying metabolic patterns associated with disease Foreword written by Professor Dame Sally Davies who is the Chief Medical Officer for England
Metabolome Analyses
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Author : Seetharaman Vaidyanathan
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-20
Metabolome Analyses written by Seetharaman Vaidyanathan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-20 with Science categories.
Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems.
Global Metabolic Profiling
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Author :
language : en
Publisher:
Release Date : 2014
Global Metabolic Profiling written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Metabolomics Metabonomics And Metabolite Profiling
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Author : William J. Griffiths
language : en
Publisher: Royal Society of Chemistry
Release Date : 2008
Metabolomics Metabonomics And Metabolite Profiling written by William J. Griffiths and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
In this comprehensive resource the Editor draws together experts from the field and provides an insightful introduction into the technology and methodology.
Metabolomics
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Author : Wolfram Weckwerth
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
Metabolomics written by Wolfram Weckwerth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.
Metabolomics: Methods and Protocols examines the state-of-the-art in metabolomic analysis. Leading researchers in the field present protocols for the application of complementary analytical methods, such as gas chromatography-mass spectrometry (GC-MS). Metabolomics: Methods and Protocols contains forward-looking protocols, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies.
The Handbook Of Metabonomics And Metabolomics
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Author : John C. Lindon
language : en
Publisher: Elsevier
Release Date : 2011-08-11
The Handbook Of Metabonomics And Metabolomics written by John C. Lindon and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-11 with Science categories.
Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications. * comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies* aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification* covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.