Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis

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Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis

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Author : George G. Harrigan
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-01-31

Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis written by George G. Harrigan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-31 with Medical categories.

It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.

Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis

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Author : George G. Harrigan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis written by George G. Harrigan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.

Metabolome Analyses

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Author : Seetharaman Vaidyanathan
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-20

Metabolome Analyses written by Seetharaman Vaidyanathan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-20 with Computers categories.

Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems.

The Evolution From Protein Chemistry To Proteomics

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Author : Roger L. Lundblad
language : en
Publisher: CRC Press
Release Date : 2005-10-14

The Evolution From Protein Chemistry To Proteomics written by Roger L. Lundblad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-14 with Medical categories.

Largely driven by major improvements in the analytical capability of mass spectrometry, proteomics is being applied to broader areas of experimental biology, ranging from oncology research to plant biology to environmental health. However, while it has already eclipsed solution protein chemistry as a discipline, it is still essentially an extension

Exploring The Genetic Correlation Between Periodontal And Respiratory Diseases

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Author : Pooja Singh
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2024-03-21

Exploring The Genetic Correlation Between Periodontal And Respiratory Diseases written by Pooja Singh and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-21 with Medical categories.

Delve into the intricate genetic ties between periodontitis and respiratory disease in this illuminating book. Synthesizing current research, it elucidates shared genetic risk factors and pathways, enriching our understanding of their complex interconnection. Providing insights for practitioners, it enables personalized treatment strategies, leveraging genetic insights for improved patient outcomes. Recognizing the evolving research landscape and challenges in unraveling gene-environment interactions, it underscores the necessity for targeted interventions and individualized therapies. With its comprehensive overview, this book empowers researchers and healthcare professionals, paving the way for advanced approaches to prevention, diagnosis, and treatment in this vital field.

Ecometabolomics

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Author : Sumira Jan
language : en
Publisher: Academic Press
Release Date : 2019-03-10

Ecometabolomics written by Sumira Jan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-10 with Science categories.

Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics. - Provides an in-depth overview of the basics of the discipline, including non-targeted analysis and quantification of plant metabolites - Outlines the applications of various analytical techniques in comprehending the total metabolome of the organism - Covers both NMR and MS-based approaches

Molecular Diagnostics Promises And Possibilities

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Author : Mousumi Debnath
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-29

Molecular Diagnostics Promises And Possibilities written by Mousumi Debnath and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-29 with Medical categories.

A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the laboratory, they may not be well acquainted with methodologies, which can be used to work out some of their own research problems. The picture is more blurred when the molecular diagnostic tools are to be used by physicians, scientists and technicians working in diagnostic laboratories in hospitals, industry and academic institutions. Since many of them are not trained in basics of these methods, they come across several gray areas in understanding of these tools. The accurate application of molecular diagnostic tools demands in depth understanding of the methodology for precise detection of the abnormal condition of living body. To meet the requirements of a good book on molecular diagnostics of students, physicians, scientists working in agricultural, veterinary, medical and pharmaceutical sciences, it needs to expose the reader lucidly to: Give basic science behind commonly used tools in diagnostics Expose the readers to detailed applications of these tools and Make them aware the availability of such diagnostic tools The book will attract additional audience of pathologists, medical microbiologists, pharmaceutical sciences, agricultural scientists and veterinary doctors if the following topics are incorporated at appropriate places in Unit II or separately as a part of Unit-III in the book. Molecular diagnosis of diseases in agricultural crops Molecular diagnosis of veterinary diseases. Molecular epidemiology, which helps to differentiate various epidemic strains and sources of disease outbreaks. Even in different units of the same hospital, the infections could be by different strains of the same species and the information becomes valuable for infection control strategies. Drug resistance is a growing problem for bacterial, fungal and parasitic microbes and the molecular biology tools can help to detect the drug resistance genes without the cultivation and in vitro sensitivity testing. Molecular diagnostics offers faster help in the selection of the proper antibiotic for the treatment of tuberculosis, which is a major problem of the in the developing world. The conventional culture and drug sensitivity testing of tuberculosis bacilli is laborious and time consuming, whereas molecular diagnosis offers rapid drug resistant gene detection even from direct clinical samples. The same approach for HIV, malaria and many more diseases needs to be considered. Molecular diagnostics in the detection of diseases during foetal life is an upcoming area in the foetal medicine in case of genetic abnormalities and infectious like TORCH complex etc. The book will be equally useful to students, scientists and professionals working in the field of molecular diagnostics.

Advances In Microbial Physiology

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Author :
language : en
Publisher: Elsevier
Release Date : 2007-09-06

Advances In Microbial Physiology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-06 with Science categories.

Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, the editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to "traditional views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series.

Obesity

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Author : Karine Clement
language : en
Publisher: CRC Press
Release Date : 2007-09-12

Obesity written by Karine Clement and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-12 with Medical categories.

This book comprehensively accounts the current understanding of genetic mechanisms of obesity by analyzing obesity phenotypes and genotypes and, gene polymorphisms and mutations, and current results from animal model research and genetic studies in human models. By presenting the impact of genetic factors in the development of obesity and key molec

Biological Concepts And Techniques In Toxicology

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Author : Jim E. Riviere
language : en
Publisher: CRC Press
Release Date : 2006-03-06

Biological Concepts And Techniques In Toxicology written by Jim E. Riviere and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Medical categories.

Highlighting the latest advances in molecular biology, mathematical modeling, quantitative risk assessment, and biopharmaceutical development, this reference presents how current scientific applications and methods impact and revolutionize mainstream toxicological research. Presenting findings from disciplines that will impact the future of toxicol