The Evolution From Protein Chemistry To Proteomics
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The Evolution From Protein Chemistry To Proteomics
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Author : Roger L. Lundblad
language : en
Publisher: CRC Press
Release Date : 2005-10-14
The Evolution From Protein Chemistry To Proteomics written by Roger L. Lundblad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-14 with Medical categories.
Largely driven by major improvements in the analytical capability of mass spectrometry, proteomics is being applied to broader areas of experimental biology, ranging from oncology research to plant biology to environmental health. However, while it has already eclipsed solution protein chemistry as a discipline, it is still essentially an extension
Proteomics For Biological Discovery
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Author : Timothy D. Veenstra
language : en
Publisher: John Wiley & Sons
Release Date : 2006-06-12
Proteomics For Biological Discovery written by Timothy D. Veenstra and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-12 with Science categories.
Written by recognized experts in the study of proteins, Proteomics for Biological Discovery begins by discussing the emergence of proteomics from genome sequencing projects and a summary of potential answers to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are then dealt with in terms of underlying concepts, limitations and future directions. An invaluable source of information, this title also provides a thorough overview of the current developments in post-translational modification studies, structural proteomics, biochemical proteomics, microfabrication, applied proteomics, and bioinformatics relevant to proteomics. Presents a comprehensive and coherent review of the major issues faced in terms of technology development, bioinformatics, strategic approaches, and applications Chapters offer a rigorous overview with summary of limitations, emerging approaches, questions, and realistic future industry and basic science applications Discusses higher level integrative aspects, including technical challenges and applications for drug discovery Accessible to the novice while providing experienced investigators essential information Proteomics for Biological Discovery is an essential resource for students, postdoctoral fellows, and researchers across all fields of biomedical research, including biochemistry, protein chemistry, molecular genetics, cell/developmental biology, and bioinformatics.
From Genome To Proteome
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Author : Michael J. Dunn
language : en
Publisher: John Wiley & Sons
Release Date : 2008-11-21
From Genome To Proteome written by Michael J. Dunn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-21 with Science categories.
As research on the human, animal, plant and microbial genomes matures towards descriptive fullness, the need for understanding the proteome has clearly emerged as the next major endeavor of life sciences. Proteomics - the quantitative analysis of all proteins working in a cell at a specific time and at specific conditions - provides deep insight into the highly organized network of expression, modification and degradation of proteins. Compiled in this book are reviews and research articles which describe the recent advances and perspectives of this new field of research. The articles are grouped into the following sections: - Sample Preparation and Solubilization - Developments in Electrophoresis - Detection and Quantitation - Mass Spectrometry - Proteome Data Analysis and Management - Prokayotes and Yeast - Biological Fluids - Eukaryotic Cells and Tissue - Oncology - Plants Proteomics is a new key for the functional analysis of living systems and of equal importance for basic as well as application oriented research.
Proteomics In Functional Genomics
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Author : P. Jolles
language : en
Publisher: Birkhäuser
Release Date : 2013-03-11
Proteomics In Functional Genomics written by P. Jolles and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-11 with Science categories.
A wealth of information has accumulated over the last few years on the human genome. The new insights have completely changed the focus of protein analysis. It is no longer time-consuming analysis of unknown products, but rather selective identifications of individual forms, modifications and processings, and overall analysis of global protein outputs from cells and tissues in health and disease. This book gears to the rising need of sensitive, accurate, and fast separation and identification techniques in proteomics. It discusses current methodologies of modern protein analysis, from isolation and sample preparation, over analysis and identification, to final characterization. Several evaluations concentrate on the now productive approaches of two-dimensional gel electrophoresis and mass spectrometry, but alternative methods and further perspectives are also outlined. The book includes an overlook over current databases to connect protein analysis data with all available information,...
Proteome Analysis
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Author : David W Speicher
language : en
Publisher: Elsevier
Release Date : 2004-05-18
Proteome Analysis written by David W Speicher and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-05-18 with Science categories.
This book explores the current status of proteomics, an exciting new discipline, which is less than 10 years old. This new field has rapidly grown into a major commercial and research enterprise with great prospects for dramatically advancing our knowledge of basic biological and disease processes. The contributors to this book are an international panel of proteomics experts, who review and discuss the current status of specific technologies and approaches. Proteomics represents an exciting new way to pursue biological and biomedical science at an unprecedented pace. Proteomics takes a broad, comprehensive, systematic approach to understanding biology that is generally unbiased and not dependent upon existing knowledge. The major components of proteomics from basic discovery using a range of alternative analytical methods to discovery validation and use for clinical applications are discussed. State-of-the-art protein profiling methods include high resolution two-dimensional gels, two-dimensional differential in-gel electrophoresis, LC-MS and LC-MS/MS using accurate mass tags, and protein identifications of proteins from gels using mass spectrometry methods are discussed in depth. Other chapters describe comprehensive characterization of proteomes using electrophoretic prefractionation and analyses of sub-proteomes based on specific posttranslational modifications including the phospho-proteome, the glyco-proteome, and nitrated proteins. These conventional proteome analysis chapters are complemented by discussion of emerging technologies and approaches such as affinity based biosensor proteomics as well as the use of protein microarrays, microfluidics and nanotechnology. Strategies for improving throughput by automation are also discussed. Additional chapters address the application of current proteome techniques to clinical problems and the availability of protein expression library resources for proteome studies. · Authored by international experts in the field · Covers a wide range of topics including 2-D gels, global proteomics using accurate mass tags, global proteomics using electrophoretic prefractionation, microfluidics, and nanotechnology · Includes state-of-the-art protein profiling methods, and emerging technologies
Emerging Sample Treatments In Proteomics
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Author : José-Luis Capelo-Martínez
language : en
Publisher: Springer
Release Date : 2019-06-24
Emerging Sample Treatments In Proteomics written by José-Luis Capelo-Martínez and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-24 with Science categories.
Proteomics is a well-established area of Science; yet with a strong area in constant evolution, namely sample treatment. There few books that currently cover the field of emerging sample treatments in proteomics, this new volume will be the first to cover all emerging and existing studies. This unique book presents the latest advances in the field focusing on emerging trends linked to high-resolution mass spectrometry, technology addressed to treat samples faster and to attempts to simplify the proteome for the reader.
Proteomics
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Author : Tsz Kwong Man
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-02-10
Proteomics written by Tsz Kwong Man and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-10 with Science categories.
Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research.
Principles Of Proteomics
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Author : Richard Twyman
language : en
Publisher: Garland Science
Release Date : 2004-05-01
Principles Of Proteomics written by Richard Twyman and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-05-01 with Science categories.
Principles of Proteomics is designed specifically to explain the different stages of proteomic analysis, their complexities and their jargon to students and researchers in a non-technical overview of the field. The author describes the broad range of problems which proteomics can address, including structural proteomics, interaction proteomics, protein modification analysis and functional proteomics. Methodologies are described in user-friendly language, from the more traditional two-dimensional gel electrophoresis to the new developments in protein chip technologies. These are well presented in the context of overall strategies which can be adopted to address the different aspects of large-scale protein analysis.
Proteome Characterization And Proteomics
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Author : Timothy D. Veenstra
language : en
Publisher: Academic Press
Release Date : 2003-09-04
Proteome Characterization And Proteomics written by Timothy D. Veenstra and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-04 with Science categories.
The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies. Discusses proteomics in the postgenomic age Includes various strategies for quantitative proteomics Covers the role of MS in structural functional proteomics and proteomics in drug discovery and bioinformatics
Methods In Proteome And Protein Analysis
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Author : Roza Maria Kamp
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-01-23
Methods In Proteome And Protein Analysis written by Roza Maria Kamp and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-23 with Science categories.
Following the succesful publication of "Proteome and Protein Analysis" in 2000, which was based on a former MPSA (Methods in Protein Structure Analysis) conference, "Methods in Proteome and Protein Analysis" presents the most interesting papers from the 14th MPSA meeting. Major topics include: X-ray crystallography, mass spectrometry or cryo-electron microscopy tomography and different experimental approaches for the study of very large multi-subunit molecular nanomaschines; development of high throughput methods for large-scale protein expression and purification and automatic data acquisition for structure determination by both X-ray diffraction and NMR spectroscopy; mechanisms of protein folding and misfolding in vitro and in vivo; protein-protein interactions; analysis of post-translational modifications; the classification, prediction of structure or functional sites, and evolution of protein folds and functions. TOC: Includes 25 chapters organized in the following parts: Structural Proteomics Proteome Analysis Structure-Function Correlations Protein-Protein Interaction Advanced Technologies Protein Sequencing and Amino Acids Analysis Bioinformatics