Metabolic Regulation In Cardiovascular Homeostasis And Disease

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Metabolic Regulation In Cardiovascular Homeostasis And Disease

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Author : Kunhua Song
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-12

Metabolic Regulation In Cardiovascular Homeostasis And Disease written by Kunhua Song and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with Medical categories.

Metabolic Regulation In The Development Of Cardiovascular Diseases

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Author : Xiaoqiang Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-06

Metabolic Regulation In The Development Of Cardiovascular Diseases written by Xiaoqiang Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-06 with Science categories.

Regulation Of Tissue Oxygenation Second Edition

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Author : Roland N. Pittman
language : en
Publisher: Biota Publishing
Release Date : 2016-08-18

Regulation Of Tissue Oxygenation Second Edition written by Roland N. Pittman and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-18 with Medical categories.

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Adipose Tissue In The Cardiovascular Homeostasis And Disease

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Author : Thiago Bruder
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-13

Adipose Tissue In The Cardiovascular Homeostasis And Disease written by Thiago Bruder and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-13 with Science categories.

Metabolic Basis Of Obesity

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Author : Rexford S. Ahima
language : en
Publisher: Springer
Release Date : 2010-11-17

Metabolic Basis Of Obesity written by Rexford S. Ahima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-17 with Medical categories.

The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.

The Scientist S Guide To Cardiac Metabolism

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Author : Michael Schwarzer
language : en
Publisher: Academic Press
Release Date : 2015-11-04

The Scientist S Guide To Cardiac Metabolism written by Michael Schwarzer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-04 with Science categories.

The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. Provides a quick and comprehensive introduction into cardiac metabolism Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function Includes historical perspectives that reference important investigators that have contributed to the development of the field

Neural Regulation Of Metabolism

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Author : Qi Wu
language : en
Publisher: Springer
Release Date : 2018-11-02

Neural Regulation Of Metabolism written by Qi Wu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with Medical categories.

This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.

Metabolic Cardiomyopathy

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Author : H. Böhles
language : en
Publisher: CRC Press
Release Date : 2004

Metabolic Cardiomyopathy written by H. Böhles and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cardiomyopathy categories.

During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Sex And Gender Factors Affecting Metabolic Homeostasis Diabetes And Obesity

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Author : Franck Mauvais-Jarvis
language : en
Publisher: Springer
Release Date : 2017-12-08

Sex And Gender Factors Affecting Metabolic Homeostasis Diabetes And Obesity written by Franck Mauvais-Jarvis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-08 with Medical categories.

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Biology Of Cardiovascular And Metabolic Diseases

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Author : Chaya Gopalan
language : en
Publisher: Academic Press
Release Date : 2022-01-11

Biology Of Cardiovascular And Metabolic Diseases written by Chaya Gopalan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-11 with Medical categories.

Biology of Cardiovascular and Metabolic Diseases combines physiology and pathophysiology of selected metabolic and cardiovascular diseases with health relevance. Written in a concise and easy to read manner, the book allows readers to gain an understanding on a number of topics, including cardiovascular physiology and pathophysiology and how it relates to the development of insulin resistance, diabetes and other metabolic diseases. The book also highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure and way to treat underlying conditions. Focuses succinctly on the physiology and pathophysiology of cardiovascular and metabolic diseases Written in a concise and easy to read manner, allowing readers to quickly understand concepts Highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure