Metabolomics In Practice
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Metabolomics In Practice
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Author : Michael Lämmerhofer
language : en
Publisher: John Wiley & Sons
Release Date : 2013-02-14
Metabolomics In Practice written by Michael Lämmerhofer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-14 with Science categories.
Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the insight and advice offered here helps to clear the hurdles in setting up and running a successful analysis, resulting in high-quality data from every experiment. Based on more than a decade of practical experience in developing, optimizing and validating metabolomics approaches as a routine technology in the academic and industrial research laboratory, the lessons taught here are highly relevant for all systems-level approaches, whether in systems biology, biotechnology, toxicology or pharmaceutical sciences. From the Contents: * Sampling and Sample Preparation in Microbial Metabolomics * Tandem Mass Spectrometry Hyphenated with HPLC and UHPLC for Targeted Metabolomics * GC-MS, LC-MS, CE-MS and Ultrahigh Resolution MS (FTICR-MS) in Metabolomics * NMR-based metabolomics analysis * Potential of Microfluidics and Single Cell Analysis in Metabolomics * Data Processing in Metabolomics * Validation and Measurement Uncertainty in Metabolomic Studies * Metabolomics and its Role in the Study of Mammalian Systems and in Plant Sciences * Metabolomics in Biotechnology and Nutritional Metabolomics and more.
High Throughput Plant Metabolomics
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Author : Jen-Tsung Chen
language : en
Publisher: CABI
Release Date : 2025-06-27
High Throughput Plant Metabolomics written by Jen-Tsung Chen and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-27 with Technology & Engineering categories.
This book summarizes the current achievements of metabolomics in revealing the roles of primary and secondary metabolisms of plants both used as major crops and for the production of medicines. It presents methods and applications of metabolomics for the exploration of stress responses, which may pave the way for obtaining climate-smart and stress-tolerant crops able to face biotic and abiotic stressors in a globally-changing climate. These technologies can advance the exploration of plant physiology as well as precision crop breeding for future anti-stress, high-quality, and high-yield plants and in doing so can achieve sustainable agriculture and therefore support the Sustainable Development Goals, the Paris Agreement, and the vision of sustainable agriculture. This book is an ideal reference for students, researchers, teachers, professors, and experts in the field of plant science and crop breeding. It provides an effective overview of the critical topic of plant science and will help to inspire and assist researchers as they design new experiments and methods.
Concepts In Plant Metabolomics
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Author : B.J. Nikolau
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-04-03
Concepts In Plant Metabolomics written by B.J. Nikolau and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-03 with Science categories.
Analogous to genomics, which defines all genes in a genome irrespective of their functionality, metabolomics seeks to profile "all" metabolites in a biological sample irrespective of the chemical and physical properties of these molecules. Metabolomics has the potential of defining cellular processes as it provides a measure of the ultimate phenotype of an organism, as defined by the collage of small molecules, whose levels of accumulation is altered in response to genetic and environmentally induced changes in gene expression. This book presents a guide for new practitioners of metabolomics, providing insights as to the current use and applications of metabolomics.
Metabolomics
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Author : Xianquan Zhan
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-09-01
Metabolomics written by Xianquan Zhan and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-01 with Science categories.
Metabolomics is the methodology and theory to study the metabolome, including targeted approaches based on selected/multiple reaction monitoring (SRM/MRM) and untargeted approaches based on nuclear magnetic resonance (NMR) or mass spectrometry (MS). The metabolome contains all metabolites derived from sugars, lipids, proteins, and nucleic acids in a given biological system, tissue, cell, or body fluid in a metabolic network system. Metabolomic variations directly link to molecular mechanisms of a disease, reliable therapeutic targets, and effective biomarkers for prediction, diagnosis, and prognostic assessment of disease. This book presents new advances in the concept and methodology of metabolomics, as well as applications of metabolomics in the research and practice of medical and life sciences.
Nutriomics
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Author : Devarajan Thangadurai
language : en
Publisher: CRC Press
Release Date : 2022-05-16
Nutriomics written by Devarajan Thangadurai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-16 with Health & Fitness categories.
Implementation of robust omics technologies enables integrative and holistic interrogation related to nutrition by labeling biomarkers to empirically assess the dietary intake. Nutriomics: Well-being through Nutrition aims to enhance scientific evidence based on omics technologies and effectiveness of nutrition guidelines to promote well-being. It provides deep understanding towards nutrients and genotype effects on disease and health status. It also unveils the nutrient–health relation at the population and individual scale. This book helps to design the precise nutritional recommendations for prevention or treatment of nutrition-related syndromes. Nutriomics: Well-being through Nutrition focuses on: The impact of molecular approaches to revolutionize nutrition research for human well-being Various biomarkers for bioactive ingredient analysis in nutritional intervention research Potential of transcriptomic, genomic, proteomic, metabolomic, and epigenomic tools for nutrition care practices Recent updates on applications of omics technologies towards personalized nutrition Providing comprehensive reviews about omics technologies in nutritional science, Nutriomics: Well-being through Nutrition serves as an advanced source of reference for food developers, nutritionists, and dietary researchers to investigate and evaluate nutriomics tools for development of customized nutrition and food safety. It is also a useful source for clinicians and food industry officials who require intense knowledge about emerging dietary-related tools to revolutionize the nutrition industry. This is a volume in the Food Analysis and Properties series, a series designed to provide state-of-art coverage on topics to the understanding of physical, chemical, and functional properties of foods.
Metabolomics Perspectives
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Author : Jacopo Troisi
language : en
Publisher: Academic Press
Release Date : 2022-03-15
Metabolomics Perspectives written by Jacopo Troisi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-15 with Science categories.
Metabolomics Perspectives: From Theory to Practical Application is an expertly written volume, which provides a thorough description of the current state-of-the-art in the metabolomics field. The philosophy behind the book is to guide the reader in a step-by-step exploration of metabolomics experiments, ranging from sample preparation to data extraction, analysis and interpretation, and to discuss the main current applications and future perspectives of this emerging science. Armed with critical insights, coupled with a clear writing, the book consists of three main sections. The first one introduces the pivotal theoretical fundamentals and provides a comprehensive overview of the "wet" laboratory workflow, including protocol instructions and a detailed description of experimental methods and analytical techniques. The second section covers a wide range of topics in the context of data analysis, including guidance in exploratory analysis, supervised and unsupervised machine learning approaches and validation and optimization methods. In addition to the several examples reported in the text, the book features an R package, specifically designed to perform all the described algorithms, which is hosted on a companion website (www.metabolomicsperspectives.com) together with several sets of available metabolomic data. Finally, an extensive dissertation describes the latest advances and the major fields of interest for metabolomics applications, highlighting their crucial potentials for future biomedical research. Thus, this book represents a must-read for both experienced researchers, interested in metabolomics, and newcomers to the field. - Provides an in-depth description of the metabolomics experimental workflow and its applications in life science and biomedical research - Features chapter contributions from the greatest international experts in the field - Includes an R package and several sets of metabolomics data, hosted on a companion website
The Handbook Of Metabonomics And Metabolomics
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Author : John C. Lindon
language : en
Publisher: Elsevier
Release Date : 2011-08-11
The Handbook Of Metabonomics And Metabolomics written by John C. Lindon and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-11 with Science categories.
Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.* comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies* aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification* covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.
Metabolomics
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Author : Mahbuba Rahman
language : en
Publisher: Academic Press
Release Date : 2023-01-11
Metabolomics written by Mahbuba Rahman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-11 with Science categories.
Metabolomics: A Path Towards Personalized Medicine integrates environmental factors of genomics, transcriptomics and proteomics, providing a bridge to resolve gaps between fundamental science and applications in clinical medicine and population health. The concept of personalized medicine or precision medicine is of great interest in biomedical research as it helps bring about new drug discovery and biomarker identification. In addition, it helps clinicians prescribe the right medicine to the right person with maximum efficacy and minimum toxicity, allowing clinicians to further predict the susceptibility to disease onset of vulnerable populations.The book is ideally suited for researchers and postgraduate students who are interested in clinical and non-clinical studies where metabolites are used for the identification of disease and therapeutic targets. - Gives insights on the importance of personalized medicine in clinical and research environments - Provides the principles of metabolomics - Presents applications of metabolomics in biomarker identification and drug discovery
Metabolomics
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Author : Jens Nielsen
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-19
Metabolomics written by Jens Nielsen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-19 with Science categories.
The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated with a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g., protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms. This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.
Metabolomics
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Author : Vijay Soni
language : en
Publisher: Springer Nature
Release Date : 2023-10-24
Metabolomics written by Vijay Soni and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-24 with Science categories.
This book Introduces the extensive applications of metabolomics from all possible areas of research and development so that not only an undergraduate can understand the advancement of metabolomics, but an entrepreneur can harness the knowledge to address possible problems to make a perfect tool to address their research question. Topics covered include the role of metabolomics in the development of agriculture, plant pathology, and their applications; the generalized application of the metabolomics and use of related technologies in various sectors of industries; and the future of metabolomics and upcoming related technologies that can fill the gap between different -omics and their applications for the betterment of humankind. This is an ideal book for university professors, researchers, and advanced-level scientists who are exploring different avenues in metabolomics. Availability of this concise information in one place will aid scientists by expanding their arsenal of techniques and can be helpful to bring more collaborations and to identify the expert at the global level.