Methodologies For Metabolomics
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Methodologies For Metabolomics
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Author : Norbert Winfried Lutz
language : en
Publisher:
Release Date : 2012
Methodologies For Metabolomics written by Norbert Winfried Lutz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Metabolism categories.
Metabolomics
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Author : Xianquan Zhan
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-09-01
Metabolomics written by Xianquan Zhan and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-01 with Science categories.
Metabolomics is the methodology and theory to study the metabolome, including targeted approaches based on selected/multiple reaction monitoring (SRM/MRM) and untargeted approaches based on nuclear magnetic resonance (NMR) or mass spectrometry (MS). The metabolome contains all metabolites derived from sugars, lipids, proteins, and nucleic acids in a given biological system, tissue, cell, or body fluid in a metabolic network system. Metabolomic variations directly link to molecular mechanisms of a disease, reliable therapeutic targets, and effective biomarkers for prediction, diagnosis, and prognostic assessment of disease. This book presents new advances in the concept and methodology of metabolomics, as well as applications of metabolomics in the research and practice of medical and life sciences.
Methodologies For Metabolomics
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Author : Norbert Lutz
language : en
Publisher:
Release Date : 2013
Methodologies For Metabolomics written by Norbert Lutz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with SCIENCE categories.
Methodologies for Metabolomics provides comprehensive descriptions of the newest methodological strategies and techniques in metabolomic research.
Metabolomics
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Author : Wolfram Weckwerth
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
Metabolomics written by Wolfram Weckwerth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.
Metabolomics: Methods and Protocols examines the state-of-the-art in metabolomic analysis. Leading researchers in the field present protocols for the application of complementary analytical methods, such as gas chromatography-mass spectrometry (GC-MS). Metabolomics: Methods and Protocols contains forward-looking protocols, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies.
Metabolomics In Crop Research Current And Emerging Methodologies
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Author : Marta Sousa Silva
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-18
Metabolomics In Crop Research Current And Emerging Methodologies written by Marta Sousa Silva and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-18 with categories.
The plant metabolome is highly complex, being composed of over 200,000 metabolites. The characterization of these small molecules has been crucial to study plant growth and development as well as their response to environmental changes. The potential of metabolomics in plant research, particularly if applied to crop plants, is also extremely valuable in the discovery of biomarkers and in the improvement of crop yield and quality. This Frontiers Research Topic addresses many applications of metabolomics to crop research, based on different analytical platforms, including mass spectrometry, and nuclear magnetic resonance. It comprises 13 articles from 109 authors that show the importance and the contribution of metabolomics in the analysis of crop’s traceability and genetic variation, in the study of fruit development, and in the understanding of the plant’s response to the environment and to different biotic and abiotic stresses.
Clinical Metabolomics
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Author : Martin Giera
language : en
Publisher:
Release Date : 2018
Clinical Metabolomics written by Martin Giera and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Biochemistry categories.
This detailed volume presents a comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. The methodologies explored here form the core of several very promising initiatives evolving around personalized health care and precision medicine, which can be seen as complimentary to the field of clinical chemistry and aid the aforementioned field with novel disease markers and diagnostic patterns. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.uthoritative and practical, Clinical Metabolomics: Methods and Protocols aims to serve as the basis for successful communication between scientists from several fields, including chemists, biologist, bioinformaticians, and clinicians, ultimately leading to effective study design and completion.
Methodologies For Metabolomics
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Author : Norbert W. Lutz
language : en
Publisher: Cambridge University Press
Release Date : 2013-01-21
Methodologies For Metabolomics written by Norbert W. Lutz and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-21 with Medical categories.
Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.
Chromatographic Methods In Metabolomics
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Author : Tuulia Hyotylainen
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013
Chromatographic Methods In Metabolomics written by Tuulia Hyotylainen and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Science categories.
Intends to present chromatographic techniques in metabolomics in a fundamental way. This book covers the chromatographic techniques, such as liquid chromatography, gas chromatography, comprehensive two-dimensional gas chromatography and electrochromatographic techniques utilised in metabolomics.
Advanced Mass Spectrometry Based Analytical Separation Techniques For Probing The Polar Metabolome
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Author : Rawi Ramautar
language : en
Publisher: Royal Society of Chemistry
Release Date : 2021-07-21
Advanced Mass Spectrometry Based Analytical Separation Techniques For Probing The Polar Metabolome written by Rawi Ramautar and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-21 with Science categories.
Discussing the state-of-the-art of the proposed topics in one single book for probing the polar metabolome, using relevant examples, is unique and needed in the metabolomics field.
Proteomic And Metabolomic Approaches To Biomarker Discovery
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Author : Haleem J. Issaq
language : en
Publisher: Academic Press
Release Date : 2013-05-20
Proteomic And Metabolomic Approaches To Biomarker Discovery written by Haleem J. Issaq and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-20 with Science categories.
Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research. Describes the use of biomarkers to reduce clinical errors in research Includes techniques from a range of biomarker discoveries Covers all steps involved in biomarker discovery, from study design to study execution