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Metabolomics From Fundamentals To Clinical Applications


Metabolomics From Fundamentals To Clinical Applications
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Metabolomics From Fundamentals To Clinical Applications


Metabolomics From Fundamentals To Clinical Applications
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Author : Alessandra Sussulini
language : en
Publisher: Springer
Release Date : 2018-06-09

Metabolomics From Fundamentals To Clinical Applications written by Alessandra Sussulini and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-09 with Science categories.


This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.



Metabolomics From Fundamentals To Clinical Applications


Metabolomics From Fundamentals To Clinical Applications
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Author : Alessandra Sussulini
language : en
Publisher: Springer
Release Date : 2017-01-28

Metabolomics From Fundamentals To Clinical Applications written by Alessandra Sussulini and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-28 with Science categories.


This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.



Ion Mobility Mass Spectrometry


Ion Mobility Mass Spectrometry
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Author : Alison E Ashcroft
language : en
Publisher: Royal Society of Chemistry
Release Date : 2021-11-11

Ion Mobility Mass Spectrometry written by Alison E Ashcroft and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-11 with Science categories.


Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields.



Separation Techniques Applied To Omics Sciences


Separation Techniques Applied To Omics Sciences
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Author : Ana Valéria Colnaghi Simionato
language : en
Publisher: Springer Nature
Release Date : 2021-10-09

Separation Techniques Applied To Omics Sciences written by Ana Valéria Colnaghi Simionato and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-09 with Science categories.


This book covers liquid chromatography, gas chromatography and capillary electrophoresis, the three main separation techniques lately available, applied to key omic sciences, such as genomics, proteomics, metabolomics and foodomics. The fundamentals of each technique are not covered herein. Instead, the recent advances in such techniques are presented focusing on the application to omics analyses and unique aspects in each case. This volume intends to offer wide ranging options available to researchers on omics sciences, and how to integrate them in order to achieve the comprehension of a biological system as a whole. Omic sciences have been of ultimate importance to comprehend the complex biochemical reactions and related events that occurs upon a biological system. The classical central dogma of molecular biology, which states that genetic information flows unidirectionally from DNA to RNA and then to proteins, has been gradually replaced by the systems biology approach. This book presents a multidisciplinary approach that explains the biological system as a whole, where the entire organism is influenced by a variety of internal events as well as by the environment, showing that each level of the biological information flux may influence the previous or the subsequent one.



Handbook Of Bioanalytics


Handbook Of Bioanalytics
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Author : Bogusław Buszewski
language : en
Publisher: Springer Nature
Release Date : 2022-06-30

Handbook Of Bioanalytics written by Bogusław Buszewski and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-30 with Science categories.


This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.



Bioremediation For Environmental Pollutants


Bioremediation For Environmental Pollutants
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Author : Inamuddin
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-06-23

Bioremediation For Environmental Pollutants written by Inamuddin and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-23 with Science categories.


Increased industrial and agricultural activity has led to the contamination of the earth's soil and groundwater resources with hazardous chemicals. The presence of heavy metals, dyes, fluorides, dissolved solids, and many other pollutants used in industry and agriculture are responsible for hazardous levels of water pollution. The removal of these pollutants in water resources is challenging. Bioremediation is a new technique that employs living organisms, usually bacteria and fungi, to remove pollutants from soil and water, preferably in situ. This approach is more cost-effective than traditional techniques, such as incineration of soils and carbon filtration of water. It requires understanding how organisms consume and transform polluting chemicals, survive in polluted environments, and how they should be employed in the field. Bioremediation for Environmental Pollutants discusses the latest research in green chemistry and practices and principles involved in quality improvement of water by remediation. It covers different aspects of environmental problems and their remedies with up-to-date developments in the field of bioremediation of industrial/environmental pollutants. Volume 2 explains the methods used to control the remediation processes making it cost-effectively and feasible. It elaborates on the application of microbial enzymes, microalgae, and genetically engineered microorganisms in the bioremediation of significant pollutants, food wastes, distillery wastewater, and pharmaceutical wastes. This book is invaluable for researchers and scientists in environmental science, environmental microbiology, and waste management. It also serves as a learning resource for graduate and undergraduate students in environmental science, microbiology, limnology, freshwater ecology, and microbial biotechnology.



Multi Pronged Omics Technologies To Understand Covid 19


Multi Pronged Omics Technologies To Understand Covid 19
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Author : Sanjeeva Srivastava
language : en
Publisher: CRC Press
Release Date : 2022-07-07

Multi Pronged Omics Technologies To Understand Covid 19 written by Sanjeeva Srivastava and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-07 with Science categories.


"COVID-19 and Omics Technologies" is a comprehensive, integrative assessment of recent information and knowledge collected on SARS-CoV-2 and COVID-19 during the pandemic based on omics technologies. It demonstrates how omics technologies could better investigate the infectious disease and propose solutions to the current concerns. The value of multi-omics technologies in understanding disease etiology and host response, discovering infection biomarkers and illness prediction, identifying vaccine candidates, discovering therapeutic targets, and tracing pathogen evolution is discussed in this book. These factors combine to make it a valuable resource to enhance understanding of both "Omics technology" and "COVID-19" as a disease. The book covers the most recent understanding of COVID-19 and the applications of cutting-edge studies, making it accessible to a large multidisciplinary readership. The book explains how high-throughput technologies and systems biology might assist to solve the pandemic’s challenges and deconstruct and appreciate the substantial contributions that omics technologies have made in predicting the path of this unforeseeable pandemic. Features: In-depth summary of clinical presentation, epidemiological impact, and long-term sequelae of COVID-19 pandemic. A systematic overview of omics-based approaches to the study of COVID-19 biology. Recent research results and some pointers to future advancements in methodologies used. Detailed examples from recent studies on COVID-19 encompassing different omics methodologies. A detailed description of methodologies and notes on the applications of state-of-the-art technologies. This book is intended for scientists who need to understand the biology of COVID-19 from the perspective of omics investigations, as well as researchers who want to employ omics-based technologies in disease biology.



Bioinformatics In Agriculture


Bioinformatics In Agriculture
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Author : Pradeep Sharma
language : en
Publisher: Academic Press
Release Date : 2022-04-28

Bioinformatics In Agriculture written by Pradeep Sharma and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-28 with Technology & Engineering categories.


Bioinformatics in Agriculture: Next Generation Sequencing Era is a comprehensive volume presenting an integrated research and development approach to the practical application of genomics to improve agricultural crops. Exploring both the theoretical and applied aspects of computational biology, and focusing on the innovation processes, the book highlights the increased productivity of a translational approach. Presented in four sections and including insights from experts from around the world, the book includes: Section I: Bioinformatics and Next Generation Sequencing Technologies; Section II: Omics Application; Section III: Data mining and Markers Discovery; Section IV: Artificial Intelligence and Agribots. Bioinformatics in Agriculture: Next Generation Sequencing Era explores deep sequencing, NGS, genomic, transcriptome analysis and multiplexing, highlighting practices forreducing time, cost, and effort for the analysis of gene as they are pooled, and sequenced. Readers will gain real-world information on computational biology, genomics, applied data mining, machine learning, and artificial intelligence. This book serves as a complete package for advanced undergraduate students, researchers, and scientists with an interest in bioinformatics. - Discusses integral aspects of molecular biology and pivotal tool sfor molecular breeding - Enables breeders to design cost-effective and efficient breeding strategies - Provides examples ofinnovative genome-wide marker (SSR, SNP) discovery - Explores both the theoretical and practical aspects of computational biology with focus on innovation processes - Covers recent trends of bioinformatics and different tools and techniques



Nutriomics


Nutriomics
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Author : Devarajan Thangadurai
language : en
Publisher: CRC Press
Release Date : 2022-05-16

Nutriomics written by Devarajan Thangadurai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-16 with Health & Fitness categories.


Implementation of robust omics technologies enables integrative and holistic interrogation related to nutrition by labeling biomarkers to empirically assess the dietary intake. Nutriomics: Well-being through Nutrition aims to enhance scientific evidence based on omics technologies and effectiveness of nutrition guidelines to promote well-being. It provides deep understanding towards nutrients and genotype effects on disease and health status. It also unveils the nutrient–health relation at the population and individual scale. This book helps to design the precise nutritional recommendations for prevention or treatment of nutrition-related syndromes. Nutriomics: Well-being through Nutrition focuses on: The impact of molecular approaches to revolutionize nutrition research for human well-being Various biomarkers for bioactive ingredient analysis in nutritional intervention research Potential of transcriptomic, genomic, proteomic, metabolomic, and epigenomic tools for nutrition care practices Recent updates on applications of omics technologies towards personalized nutrition Providing comprehensive reviews about omics technologies in nutritional science, Nutriomics: Well-being through Nutrition serves as an advanced source of reference for food developers, nutritionists, and dietary researchers to investigate and evaluate nutriomics tools for development of customized nutrition and food safety. It is also a useful source for clinicians and food industry officials who require intense knowledge about emerging dietary-related tools to revolutionize the nutrition industry. This is a volume in the Food Analysis and Properties series, a series designed to provide state-of-art coverage on topics to the understanding of physical, chemical, and functional properties of foods.



Biomarkers For Huntington S Disease


Biomarkers For Huntington S Disease
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Author : Elizabeth A. Thomas
language : en
Publisher: Springer Nature
Release Date : 2023-10-12

Biomarkers For Huntington S Disease written by Elizabeth A. Thomas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-12 with Medical categories.


Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents a distinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important.