Methods In Computational Genomics

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Kernel Methods In Computational Biology

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Author : Bernhard Schölkopf
language : en
Publisher: MIT Press
Release Date : 2004

Kernel Methods In Computational Biology written by Bernhard Schölkopf and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Computers categories.

A detailed overview of current research in kernel methods and their application to computational biology.

Computational Genomics With R

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Author : Altuna Akalin
language : en
Publisher: CRC Press
Release Date : 2020-12-16

Computational Genomics With R written by Altuna Akalin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-16 with Mathematics categories.

Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Computational Genome Analysis

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Author : Richard C. Deonier
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-27

Computational Genome Analysis written by Richard C. Deonier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-27 with Computers categories.

This book presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book features a free download of the R software statistics package and the text provides great crossover material that is interesting and accessible to students in biology, mathematics, statistics and computer science. More than 100 illustrations and diagrams reinforce concepts and present key results from the primary literature. Exercises are given at the end of chapters.

Fundamentals Of Bioinformatics And Computational Biology

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Author : Gautam B. Singh
language : en
Publisher: Springer
Release Date : 2014-09-24

Fundamentals Of Bioinformatics And Computational Biology written by Gautam B. Singh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-24 with Technology & Engineering categories.

This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolboxTM. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today’s biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.

Methods In Computational Genomics

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Author : Nathan Olson
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-06

Methods In Computational Genomics written by Nathan Olson and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-06 with Science categories.

Computational Genomics And Structural Bioinformatics In Microbial Science

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Author : Javid Ahmad Parray
language : en
Publisher: Academic Press
Release Date : 2025-02-24

Computational Genomics And Structural Bioinformatics In Microbial Science written by Javid Ahmad Parray and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-24 with Science categories.

Computational Genomics and Structural Bioinformatics in Microbial Science: Microbial Genomics (Volume 2) covers different aspects of microbial genomics, metagenomics, and functional studies of microbes through informative illustrations of current trends in computational tools and bioinformatics approach in environmental microbiology and clinical diagnosis. This book aims to provide readers with an overview of the microbial genome, computational genomics, and structural bioinformatics in microbial science, as well as the most recent developments in these fields. This book covers a range of topics, including the challenges and opportunities of computational epigenomics, bioinformatics tools for assessing metagenomic data, as well as computed comparative genomics and computational phenotyping of microorganisms relevant to agriculture. Microbial Genomics: Host Adaptation, virulence, and Evolution is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, that are interested in microbial science specifically related to the microbial genome, computing genomics, and bioinformatics. - Provides informative illustrations of current trends in computational tools and bioinformatics approach - Presents bioinformatics of next generation sequencing in clinical microbiology diagnosis - Discusses structural bioinformatics and its applications

Insights In Computational Genomics 2022

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Author : Richard D. Emes
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-15

Insights In Computational Genomics 2022 written by Richard D. Emes and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-15 with Science categories.

This Research Topic is part of the Insights in Frontiers in Genetics series. Other titles in the series are: Genetics, Insights in Evolutionary and Population Genetics: 2022 Genetics, Insights in Livestock Genomics: 2022 Genetics, Insights in Epigenomics and Epigenetics: 2022 Genetics, Insights in Behavioral and Psychiatric Genetics: 2022 Genetics, Insights in Neurogenomics: 2022 Genetics, Insights in Genomic Assay Technology: 2022 Genetics, Insights in Genetics of Common and Rare Diseases: 2022 We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Genetics. Frontiers have organized a series of Research Topics to highlight the latest advancements in research across the field of Computational Genomics, with articles from the members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Prof Richard Emes, Specialty Chief Editor of the Computational Genomics section, together with Dr. Pirooznia and Dr Zou, focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Computational Genomics. The Research Topic solicits brief, forward-looking contributions from the editorial board members that describe the state of the art, outlining recent developments and major accomplishments that have been achieved and that need to occur to move the field forward. Authors are encouraged to identify the greatest challenges in the sub-disciplines, and how to address those challenges.

Applications And Methods In Genomic Networks

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Author : Kimberly Glass
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-01

Applications And Methods In Genomic Networks written by Kimberly Glass and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-01 with Science categories.

Computational Genomics

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Author : Nikola Stojanovic
language : en
Publisher:
Release Date : 2007

Computational Genomics written by Nikola Stojanovic and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.