Methods In Immunotoxicology
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Methods In Immunotoxicology
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Author : Gary R. Burleson
language : en
Publisher: Wiley-Blackwell
Release Date : 1995
Methods In Immunotoxicology written by Gary R. Burleson and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.
This two-volume set provides comprehensive coverage of recent and novel approaches for the identification and characterization of immunotoxicants. The first work presents an overview of the field, discussion of experimental design, and methods for risk assessment and sound laboratory practice. Volume 2 covers macrophage function assays, the use of animal models with specific reference to heat resistance, and autoimmunity.
Principles And Methods Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Elsevier
Release Date : 2004-10-14
Principles And Methods Of Immunotoxicology written by Jacques Descotes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-14 with Science categories.
This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.
Methods In Immunotoxicology
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Author : Gary R. Burleson
language : en
Publisher:
Release Date : 1995
Methods In Immunotoxicology written by Gary R. Burleson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Immune system categories.
Methods In Immunotoxicology
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Author : Gary R. Burleson
language : en
Publisher:
Release Date : 1995
Methods In Immunotoxicology written by Gary R. Burleson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Immune system categories.
Immunotoxicology Of Drugs And Chemicals Principles And Methods Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Elsevier Science Serials
Release Date : 2004
Immunotoxicology Of Drugs And Chemicals Principles And Methods Of Immunotoxicology written by Jacques Descotes and has been published by Elsevier Science Serials this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
This third thoroughly revised edition, written by a renowned expert in this rapidly expanding field, is a welcome and timely publication in the field of experimental and clinical immunotoxicology. Immunotoxicology is a young, but rapidly expanding area of toxicology. Since the second edition of this book was published in 1988, an increasing amount of data has resulted in the publication of many articles and reviews. This book covers the many general facets of current immunotoxicology - clinical, experimental, mechanistic and regulatory aspects, including a chapter on the immune system giving toxicologists unfamiliar with immunology the opportunity to acquire the minimal knowledge necessary to conduct and interpret immunotoxicity studies. A comprehensive chapter on adverse effects in relation to immunotoxicity is included in order to predict and understand the toxic effects of drugs and other chemicals in living beings. An effort is made to answer one of the perhaps most confusing issues confronting the student of immunotoxicology namely the identification of what constitutes an immunotoxic response and what does not. Researchers from different disciplines have shown interest in this new field, and presented results of their work on immunotoxicological issues from extremely varied perspectives. As a bridging discipline between immunology and toxicology, immunotoxicology is genuinely multidisciplinary, reflected in this excellent book.
Immunotoxicity Testing
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Author : Rodney R. Dietert
language : en
Publisher: Humana
Release Date : 2016-08-23
Immunotoxicity Testing written by Rodney R. Dietert and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.
Recent critical advances in the field of immunotoxicology have led to incredible contributions to basic science, including crucial improvements in human risk assessment. In Immunotoxicity Testing: Methods and Protocols, expert researchers explore these changes, providing the reader with current, lab-ready procedures, along with the corresponding background information that is necessary to identify effective testing approaches for chemicals and drugs. Among the first volumes to meld consideration of immunotoxicity testing strategies with a comprehensive presentation of detailed laboratory protocols, chapters include a description of the evolution of immunotoxicity testing, a look at the importance of immunotoxicity testing for health risk reduction, and ideas concerning the future of the field. Composed in the highly successful Methods in Molecular Biology(tm) series format, most chapters contain a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips from the experts on troubleshooting and avoiding known pitfalls. Comprehensive and innovative, Immunotoxicity Testing: Methods and Protocols is a critical, one-stop reference resource for the most important and commonly used laboratory protocols in immunotoxicology.
Introduction To Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Introduction To Immunotoxicology written by Jacques Descotes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Medical categories.
This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.
Methods In Immunotoxicology Vol 1 2
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Author : G.R. Burleson
language : en
Publisher:
Release Date : 1995
Methods In Immunotoxicology Vol 1 2 written by G.R. Burleson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.
History Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Academic Press
Release Date : 2019-04-15
History Of Immunotoxicology written by Jacques Descotes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Medical categories.
History of Immunotoxicology offers the first book-length exploration of the development and importance of the field of immunotoxicology, describing the adverse health effects involving the immune system, hypersensitivity and autoimmunity. It explores new avenues of research and immunotoxicity evaluation, regulatory aspects of immunotoxicology, and the withdrawal/banning from the market of several approved drugs and chemicals due to their immunotoxic effects. In addition, clinical manifestations of immunotoxicity, such as anaphylaxis, opportunistic infections, lymphomas, cytokine storm, and immunotherapy are addressed. Finally, the book considers how the recent past can provide insights on the future practice of immunotoxicology. As preventive measures are implemented to reduce risks, including banning of chemicals or applications of one given chemical, current toxicologists may not be aware of the toxicity potential of chemicals. This book will be of interest to students and researchers in government, industry and academia who have an interest in immunotoxicology. Examines the development of immunotoxicology Provides context to current debates on the actual toxicity potential of chemicals Covers major developments and areas of immunotoxicology
Principles And Methods For Assessing Direct Immunotoxicity Associated With Exposure To Chemicals
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Author : World Health Organization
language : en
Publisher:
Release Date : 1996
Principles And Methods For Assessing Direct Immunotoxicity Associated With Exposure To Chemicals written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
A comprehensive guide to general strategies and specific methods for testing the immunotoxicity of chemicals in animal models and humans. Addressed to those seeking a basic introduction to the field as well as specialist researchers the book takes its focus from growing concern in scientific and public communities about the capacity of environmental agents to disrupt normal immune functions and thus increase susceptibility to tumours and infectious diseases. Compounds known to adversely affect the immune system are numerous and include drugs pesticides solvents halogenated and aromatic hydrocarbons and metals. The book draws on considerable recent progress in understanding the immunological consequences of chemical insults as well as increasingly sophisticated methodologies for assessing such effects. Close to 1000 references are included in this authoritative guide. The book opens with a detailed basic introduction to immunotoxicology. An extensive explanation of the function histophysiology and pathophysiology of the immune system emphasizes features that can aid the understanding and interpretation of the pathological changes caused by immunotoxic insults. Chapter two on the health impact of selected immunotoxic agents gives illustrative examples for some 30 chemicals that have been shown to exert immunotoxic effects in laboratory animals and for an additional seven groups of chemicals known to disturb immune functions in humans. For each brief discussions illustrate the chemical's distinct immunosuppressive properties and the mechanisms by which it exerts its toxic effects on the immune system. Chapter three provides detailed descriptions of a number of tests used in a tiered approach to the assessment of immunotoxicity. Against this background specific nonfunctional and functional tests for the assessment of immunotoxicology in experimental animals are presented and explained in full detail. Information on individual tests includes an explanation of why the test is important the types of data it can yield and exactly how it should be performed. Also included are sections offering advice on assessments in non-rodent species in vitro approaches and approaches using biomarkers in epidemiological studies and monitoring. The chapter concludes with a discussion of good laboratory practices for immunotoxicology studies and procedures for the validation of tests. Chapter five explains the much more complicated procedures needed to assess immunotoxicity in humans. An explanation of general questions to be considered when designing epidemiological studies is followed by presentation of three recommended testing schemes proposed by WHO and other agencies for preliminary evaluation of individuals exposed to immunotoxicants. Specific assays for assessing immune status are also described. The final chapter outlines a step-by-step process of risk assessment specific to the evaluation of potentially immunotoxic chemicals.