Microarray Biochip Technology

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Microarray Biochip Technology

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Author : Mark Schena
language : en
Publisher: Eaton Publishing Company/Biotechniques Books
Release Date : 2000

Microarray Biochip Technology written by Mark Schena and has been published by Eaton Publishing Company/Biotechniques Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Biochips categories.

Technology standards for microarray research (M. Schena, R. W. Davis). Microfluidic technologies and instrumentation for printing DNA microarrays (Don Rose). Novel microarray printing and detection technologies (M. L. Mace Júnior, J. Montagu, Stanley D. Rose, G. McGuinness). A systems approach to fabricating and analyzing DNA microarrayss (J. Worley, K. Bechtol, S. Penn, D. Roach, D. hanzel, M. Trounstine, D. B.). The flow-thru chip: a three-dimensional biochip platform (A. Stell, M. Torres, J. Hartwell, Yong-Yi Yu, Nan Ting, G. Hoke, H. Yang). Large-scale genomic analysis using affymetrix genechip probe arrays (J. A. Warrington, S. Dee, M. Trulson). Technology and applications of gene expression microarrays (E. Evertsz, P. Starink, R. Gupta, D. Watson). Information processing issues and solutions associated with microarray technology (Y.-X. Zhou, P. Kalocsai, J.-Y. Chen, S. Shams). Microarray tools, kits, reagents, and services (T. Martinsky, P. Haje). Micromax: a highly sensitive system for differential gene expression on microarrays (K. Adler, J. Broadbent, R. Garlick, R. Joseph, A. Khimani, A. Mikulskis, P. Rapiejko, J. Killian). Production of microarrays on porous substrates using noncontact piezoelectric dispensing (D. Englert). Arrayed primer extension on the DNA chip: method and applications (N. Tonisson, A. Kurg, E. Lõhmussaar, A. Metspalu). Overview of a microarray scanner: design essentials for an integrated acquisition and analysis platform (T. Basarsky, D. Verdnik, J. Ye Zhai, D. Wellis). Selected supplier list. Index.

Biochips And Microarrays

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Author : Kewal K. Jain
language : en
Publisher:
Release Date : 2000

Biochips And Microarrays written by Kewal K. Jain and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Biochips categories.

Biochip is a broad term indicating the use of microchip technology in molecular biology. DNA microarray is a rapid method of sequencing and analyzing genes. Microarray technology is becoming a central platform for functional genomics and has been applied to gene discovery, gene expression, detection of mutation or polymorphism and gene mapping. Biochip technology has an important role to play in pharmacogenomics and molecular diagnostics. This report decribes developments and evaluates their potential applications.

Biochip Technology

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Author : Jing Cheng
language : en
Publisher: CRC Press
Release Date : 2003-09-02

Biochip Technology written by Jing Cheng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Science categories.

Biochip technology has experienced explosive growth in recent years and Biochip technology describes the basic manufacturing and fabrication processes and the current range of applications of these chips. Top scientists from the biochip industry and related areas explain the diverse applications of biochips in gene sequencing, expression monitoring, disease diagnosis, tumor examination, ligand assay and drug discovery.

Biochips

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Author : Wan-Li Xing
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Biochips written by Wan-Li Xing and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.

This book brings together contributions from internationally renowned experts in the biochip field. The authors present not only their latest research work, but also discuss current trends in biochip technology. Specific topics range from microarray technology and its applications to lab-on-a-chip technology.

Frontiers In Biochip Technology

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Author : Wan-Li Xing
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-06-18

Frontiers In Biochip Technology written by Wan-Li Xing and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-18 with Technology & Engineering categories.

Frontiers in Biochip Technology Dr. Wan-Li Xing and Dr. Jing Cheng Frontiers in Biochip Technology serves as an essential collection of new research in the field of biochip technology. This comprehensive collection covers emerging technologies and cutting –edge research in the field of biochip technology, with all chapters written by the international stars of this evolving field. Key topics and current trends in biochip technology covered include: -microarray technology and its applications - microfluidics - drug discovery - detection technology - lab-on-chip technology and bioinformatics. Frontiers in Biochip Technology is an important volume for all biotechnologists, bioengineers, genetic engineers, pharmacological researchers, and general bench researchers who want to be up-to-date on the latest advances in the rapidly growing field of biochip technology. The Editors: Dr. Wan-Li Xing, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China Dr. Xing is a Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, and also serves as the Executive Deputy Director at NERCBBT, CapitalBio Corporation, a world-leader in biochip research. Dr. Xing has published widely and obtained many patents and applications. Dr. Jing Cheng, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China Dr. Jing Cheng is the Cheung Kong Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, the Director of NERCBBT and CEO & CTO of CapitalBio. Dr. Cheng developed the world’s first system of laboratory-on-a-chip in 1998; this work was featured in the front-cover story of the June 1998 issue of Nature Biotechnology and cited as the breakthrough of the year by Science in the same year. He has been awarded Nanogen’s most prestigious award Nano Grant, Distinguished Achievement Award for Overseas Chinese Scholars Returned, China’s Science & Technology Award for Outstanding Youth, and Qiushi Technology Transfer Award for Outstanding Youth. Dr. Cheng has published over 90 peer-reviewed papers. In addition, he has obtained over 60 European and U.S. patents and applications.

Microarray Innovations

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Author : Gary Hardiman
language : en
Publisher: CRC Press
Release Date : 2009-04-02

Microarray Innovations written by Gary Hardiman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-02 with Science categories.

In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarray Innovations: Technology and Experimentation examines the incredibly powerful nature of array technology and the ways in which it can be applied to understanding the genomic basis of disease. Explores a myriad of applications in use today This volume explores recent innovations in the microarray field and tracks the evolution of the major platforms currently used. The international panel of contributors presents a survey of the past five years’ research and advancements in microarray methods and applications and their usage in drug discovery and biomedical research. The contributions discuss improvements in automation (array fabrication and hybridization), new substrates for printing arrays, platform comparisons and contrasts, experimental design, and data normalization and mining schemes. They also review epigenomic array studies, electronic microarrays, comparative genomic hybridization, microRNA arrays, and mutational analyzes. In addition, the book provides coverage of important clinical diagnostic arrays, protein arrays, and neuroscience applications. Examines improved methodologies As microarrays have evolved steadily over time from archetypical in-house complementary DNA (cDNA) arrays to robust commercial oligonucleotide platforms, there has been a migration to higher density biochips with increasing content and better analytical methodologies. This compendium summarizes the vast advances that have been made in this technology, highlighting the supreme advantages of microarray-based approaches in the field of biomedical research. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

Biochips As Pathways To Drug Discovery

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Author : Gary Hardiman
language : en
Publisher: CRC Press
Release Date : 2006-10-19

Biochips As Pathways To Drug Discovery written by Gary Hardiman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-19 with Medical categories.

In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as biochips to reduce the cost of drug discovery and improve drug safety. The book explores the tools and skills required at each step of the discovery process when using biochips to determine biological outcomes. The authors provide an in-depth review of the clinical and pharmacogenomic relevance of biochips, ChIP-chip assays, and high-throughput approaches. They discuss how biochips are used to develop biomarkers in the drug discovery process, primarily for gene expression profiling and Single Nucleotide Polymorphism (SNP) analysis. The book includes coverage of experimental theory, quality control, clinical laboratory sampling considerations, database concepts, industrial laboratory design, and the analysis of the resultant large data sets. It discusses the application of biochips to the study of malaria, toxicogenomics, and SNPs, as well as intellectual property and market overviews. The book concludes with a comprehensive overview of how these chips are employed from early target discovery through preclinical toxicology and on through to pharmacogenomic and proof of concept studies in humans. Written in an easily accessible style, the breadth of coverage introduces the subject to those new to the field, while the depth of coverage forms a foundation for future work. The book gives you the knowledge required to leverage the technology into bona fide discoveries. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

Chip Technology

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Author : Jörg Hoheisel
language : en
Publisher: Springer
Release Date : 2003-07-01

Chip Technology written by Jörg Hoheisel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-01 with Science categories.

DNA-chip analysis has come a long way since the first conference in Moscow in 1991. Nowadays, DNA-microarrays seem to be a common commodity in biological sciences. The complexity hidden behind the apparent ease of such studies, however, is highlighted by the fact that it took about ten years before the methodology really set off. Also, on closer scrutiny, one realises that some problems still remain. Nevertheless, microarrays produce data on a scale beyond imagination a few years ago. The authors of the book took part in bringing this about. They are well-known experts in the field, many - like Edwin Southern, Hans Lehrach, Radoje Drmanac, Pavel Pevzner and Charles Cantor - have been actively pursuing array technology for more than a decade. They demonstrate the continuous development in both technology and application areas and elucidate on critical points that need to be considered when performing microarray analyses.

Microarrays In Diagnostics And Biomarker Development

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Author : Bertrand Jordan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-04-23

Microarrays In Diagnostics And Biomarker Development written by Bertrand Jordan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-23 with Medical categories.

Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications. This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards “nanoarrays”, which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies.

Dna Microarrays For Biomedical Research

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Author : Martin Dufva
language : en
Publisher: Humana Press
Release Date : 2011-01-26

Dna Microarrays For Biomedical Research written by Martin Dufva and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-26 with Science categories.

DNA microarray technology has revolutionized research in the past decade. Initially an application for mRNA expression studies, the technology now has spread to other applications such as comparative genomic hybridization, SNP and mutation analysis. In DNA Microarrays for Biomedical Research: Methods and Protocols, experts explore these now commonly used applications, addressing probe design strategies, fabrication issues and providing practical examples of detailed methods for generation of high quality DNA microarray data. Chapters incorporate information on some of the largest providers of microarray, including Affymetrix, Ilumina and Agilent, and their use on a variety of applications. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Authoritative and highly practical, DNA Microarrays for Biomedical Research: Methods and Protocols presents a variety of protocols which can be easily reproduced, allowing researchers to gain surprising insight into the complex world of DNA microarray technology.