Microarrays For The Neurosciences

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Microarrays For The Neurosciences
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Author : Daniel H. Geschwind
language : en
Publisher: MIT Press
Release Date : 2002
Microarrays For The Neurosciences written by Daniel H. Geschwind and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
The effort to sequence the human genome has generated a new discipline, functional genomics, or the study of the relationship between the genetic code and its biologic potential. Gene expression studies are made possible not only by the decoding of the human genome, but by the development of new technologies. The preeminent technology in this area, DNA microarrays, is helping to revolutionize the field of neuroscience.
Dna Arrays In Neurobiology
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Author :
language : en
Publisher: Elsevier
Release Date : 2004-12-10
Dna Arrays In Neurobiology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12-10 with Medical categories.
DNA array technology is a technique for studying gene expression by comparing samples of different genes. The result is an enormous amount of data that must be carefully analyzed in order for it to be useful and meaningful. This book examines both data analysis and techniques for ensuring optimal experimental conditions. The array approach has applications in a number of model systems, including development, learning and drug abuse. In addition, the technique has applications in a number of neurological disorders such as Alzheimer's disease, schizophrenia, multiple sclerosis, and neurological cancers.
Neurosciences At The Postgenomic Era
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Author : Jacques Mallet
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Neurosciences At The Postgenomic Era written by Jacques Mallet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In this new volume in the series Research and Perspectives in Neurosciences the authors have presented and discussed their findings in the fields of speech and language disorders, X-linked mental retardation, gene therapy in the CNS, memory and learning disorders and other fields.
From Neuroscience To Neurology
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Author : Stephen Waxman
language : en
Publisher: Elsevier
Release Date : 2004-11-05
From Neuroscience To Neurology written by Stephen Waxman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-05 with Medical categories.
The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinson's disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord. The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone – clinicians and basic scientists alike – interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders.* Presents the evolution of the field of neurology into a therapeutic discipline * Discusses lessons learned from past successes and applications to ongoing work* Explores the future of this field
Methods In Genomic Neuroscience
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Author : Hemin R. Chin
language : en
Publisher: CRC Press
Release Date : 2001-09-26
Methods In Genomic Neuroscience written by Hemin R. Chin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-09-26 with Science categories.
The past few years have witnessed extraordinary advances in molecular genetic techniques and the accumulation of structural genomics information and resources in both human and model organisms. With the development of new technologies and the availability of resources like the sequence of eukaryotic genomes, problems of a previously unthinkable sco
Functional Genomics And Proteomics In The Clinical Neurosciences
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Author : Scott E. Hemby
language : en
Publisher: Elsevier
Release Date : 2006-10-09
Functional Genomics And Proteomics In The Clinical Neurosciences written by Scott E. Hemby and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-09 with Science categories.
The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression may not directly equate with protein expression. There are many potential applications for proteomics in neuroscience: determination of the neuro-proteome, comparative protein expression profiling, post-translational protein modification profiling and mapping protein-protein interactions, to name but a few. Functional Genomics and Proteomics in Clinical Neuroscience will comment on all of these applications, but with an emphasis on protein expression profiling. This book combines the basic methodology of genomics and proteomics with the current applications of such technologies in understanding psychiatric illnesses.* Introduction of basic methodologies in genomics and proteomics and their integration in psychiatry* Development of the text in sections related to methods, application and future directions of these rapidly advancing technologies* Use of actual data to illustrate many principles of functional genomics and proteomics. * Introduction to bioinformatics and database management techniques
Genomic And Molecular Neuro Oncology
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Author : Wei Zhang
language : en
Publisher: Jones & Bartlett Learning
Release Date : 2004
Genomic And Molecular Neuro Oncology written by Wei Zhang and has been published by Jones & Bartlett Learning this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
This book describes and illustrates the latest genomic and molecular techniques that are rapidly transforming the practice of clinical neuro-oncology and the direction of scientific investigation in modern brain tumor research. Each of the chapters provides a review of a specific subfield of contemporary molecular neuro-oncology, including recently implemented diagnostic and research applications. Among the important technical areas covered are the analysis of genomic instability, approaches to tumor invasion and angiogenesis, animal models, gene expression profiling, tissue microarray technology, mRNA splicing, functional genomics and genomics informatics. This book focuses on the latest genomics, molecular, and informatic approaches to neuro-oncology.
Neural Degeneration And Repair
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Author : Hans Werner Müller
language : en
Publisher: John Wiley & Sons
Release Date : 2008-03-31
Neural Degeneration And Repair written by Hans Werner Müller and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-31 with Medical categories.
Der Titel beschreibt Anwendungsmöglichkeiten der so genannten "...omics" mit dem Ziel, destruktive Vorgänge innerhalb des Nervensystems besser zu verstehen und damit neue diagnostische und therapeutische Wege für die Behandlung der schwerwiegenden neuralen Erkrankungen aufzuzeigen.
The Neuroscience Of Cocaine
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Author : Victor R Preedy
language : en
Publisher: Academic Press
Release Date : 2017-05-23
The Neuroscience Of Cocaine written by Victor R Preedy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-23 with Psychology categories.
The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine's neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse. - Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding - Illustrated in full color - Provides unique full coverage of all aspects of cocaine and its related pathology - Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms
Neuroscience For Neurologists
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Author : Patrick F. Chinnery
language : en
Publisher: World Scientific
Release Date : 2006
Neuroscience For Neurologists written by Patrick F. Chinnery and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
Written by experts in the field, this timely book presents the scientific principles behind neurology. It aims to take the reader from the human genome, through gene expression, to molecular and cellular pathology, and subsequently to contemporary clinical investigations and clinical trials. Each contribution includes a discussion about the future of the field and highlights areas of potential growth and their relevance to routine clinical practice over the next decade. The succinctly written chapters will be easily accessible to both neurologists and trainees who have no expertise in the area.