Microbial Engineering For Therapeutics
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Microbial Engineering For Therapeutics
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Author : Mrutyunjay Suar
language : en
Publisher: Springer Nature
Release Date : 2022-10-29
Microbial Engineering For Therapeutics written by Mrutyunjay Suar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-29 with Medical categories.
This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics. The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.
Principles In Microbiome Engineering
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Author : Matthew W. Chang
language : en
Publisher: John Wiley & Sons
Release Date : 2022-05-03
Principles In Microbiome Engineering written by Matthew W. Chang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-03 with Science categories.
Principles in Microbiome Engineering Provides an overview of the techniques and applications insight into the complex composition and interactions of microbiomes Microbiomes, the communities of microorganisms that inhabit specific ecosystems or organisms, can be engineered to modify the structure of microbiota and reestablish ecological balance. In recent years, a better understanding of microbial composition and host-microbe interactions has led to the development of new applications for improving human health and increasing agricultural productivity and quality. Principles in Microbiome Engineering introduces readers to the tools and applications involved in manipulating the composition of a microbial community to improve the function of an eco-system. Covering a range of key topics, this up-to-date volume discusses current research in areas such as microbiome-based therapeutics for human diseases, crop plant breeding, animal husbandry, soil engineering, food and beverage applications, and more. Divided into three sections, the text first describes the critical roles of systems biology, synthetic biology, computer modelling, and machine learning in microbiome engineering. Next, the volume explores various state-of-the-art applications, including cancer immunotherapy and prevention of diseases associated with the human microbiome, followed by a concluding section offering perspectives on the future of microbiome engineering and potential applications. Introduces a variety of applications of microbiome engineering in the fields of medicine, agriculture, and food and beverage products Presents current research into the complex interactions and relationships between microbiomes and biotic and abiotic elements of their environments Examines the use of technologies such as Artificial Intelligence (AI), Machine Learning (ML), and Big Data analytics to advance understanding of microbiomes Discusses the engineering of microbiomes to address human health conditions such as neuro psychiatric disorders and autoimmune and inflammatory diseases Edited and authored by leading researchers in the rapidly evolving field, Principles in Microbiome Engineering is an essential resource for biotechnologists, biochemists, microbiologists, pharmacologists, and practitioners working in the biotechnology and pharmaceutical industries.
Engineering Microbes For Therapy
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Author : Aleš Berlec
language : en
Publisher: Frontiers Media SA
Release Date : 2019-05-30
Engineering Microbes For Therapy written by Aleš Berlec and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-30 with categories.
Microbes can play protective role in human health, and the concepts of probiotics and microbiota have been well established in recent years. Probiotics have an important economic impact in food, food supplement and veterinary industry with increasing market size. Engineering microbes for therapy can lead to selection of new microbial strains and mixtures, or targeted improvement of existing microbial strains, achieved by mutagenesis, genetic engineering and synthetic biology. Engineering of microbes can also encompass the development and improvement of their dosage forms. Possible uses of engineered microbes include antigen delivery, immunomodulation, inflammation, cancer, infectious diseases and metabolic disorders. The eBook represents an up-to-date overview, shows new results, as well as demonstrates future trends in the developing field of therapeutic microbial engineering.
Microbial Engineering
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Author : Samuel Livingston
language : en
Publisher: Publifye AS
Release Date : 2025-02-19
Microbial Engineering written by Samuel Livingston and has been published by Publifye AS this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-19 with Science categories.
Microbial Engineering explores the revolutionary field of microbial engineering, a convergence of microbiology, molecular biology, and chemical engineering. It highlights how scientists are mastering synthetic biology to manipulate microorganisms for producing new medicines, biofuels, and other valuable products. This manipulation involves modifying microbial genomes and metabolic pathways to create biological systems with novel functions, addressing challenges such as producing therapeutic proteins or engineering microbes for bioremediation. The book underscores the potential of microbes as powerful tools that can be engineered to solve complex problems, moving beyond their traditional perception as mere agents of disease. The book uniquely combines theoretical principles with practical examples, offering a comprehensive view of the field. Beginning with foundational concepts of microbial biology and genetic engineering, it progresses through dedicated chapters on metabolic engineering, synthetic biology, and evolutionary engineering. Intriguingly, the development of restriction enzymes and recombinant DNA technology paved the way for precise manipulation of microbial genomes. The book culminates in a discussion of practical applications in medicine, industry, and environmental science, emphasizing the underlying principles of genetic engineering and offering a forward-looking perspective on emerging trends in biotechnology. Throughout the book, evidence is drawn from peer-reviewed research, scientific journals, and industry reports, presenting clear explanations and examples. Aimed at students, researchers, and professionals in biology, biotechnology, and chemical engineering, the book also addresses ethical and regulatory considerations, providing a balanced perspective on the risks and benefits. This approach makes it a valuable resource for anyone interested in the potential of microbes to solve global challenges and the science life sciences.
Synthetic Biology For Therapeutics
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Author : Urartu Ozgur Safak Seker
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2024-11-18
Synthetic Biology For Therapeutics written by Urartu Ozgur Safak Seker and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-18 with Science categories.
Synthetic biology is enabling scientists to use engineered genetic circuits in the cells as the basis for the development of new living therapeutics and as a powerful new weapon in the fight against diseases, especially cancer. Bacteria-mediated therapy is a promising alternative cancer treatment. The book covers the recent developments of cellular therapies from a synthetic biology perspective including engineered microbial therapies, CAR-T therapies etc. and is an indispensable guide to scientists in both biotechnology and medicine.
Human Microbiome In Health Disease And Therapy
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Author : Pallaval Veera Bramhachari
language : en
Publisher: Springer Nature
Release Date : 2023-12-14
Human Microbiome In Health Disease And Therapy written by Pallaval Veera Bramhachari and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-14 with Medical categories.
This book illustrates the role of the human microbiome in health and diseases. It discusses the association of an imbalanced human microbiome with different human diseases, including inflammatory, metabolic conditions, neurological, cardiovascular, and respiratory diseases. The book further reviews the association between intestinal microbiota and immune defense systems. The book provides evolving knowledge of the development, complexity, and functionality of the healthy gut microbiota and covers interventions that modulate and stabilize the gut microbiota. Further, it introduces the human microbiome as a reservoir of AMR genes, the current knowledge on the resistome, and the recent and upcoming advances in molecular diagnostic approaches to unravel this reservoir. Toward the end, the book reviews the advances in understanding the human urinary microbiome and its potential role in urinary tract infection. The chapter also presents the dynamics of the skin microbiome and the association of microbiota with skin disorders and therapeutic interventions. This book is an invaluable read for health professionals, medical students, microbiologists, and scientific research communities who are eager to update themselves with recent trends in microbiome research.
Artificial Cells Cell Engineering And Therapy
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Author : S Prakash
language : en
Publisher: Elsevier
Release Date : 2007-05-31
Artificial Cells Cell Engineering And Therapy written by S Prakash and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-31 with Science categories.
Artificial cells, cell engineering and therapy are emerging technologies which will make a significant impact on the future of medicine and healthcare. However, research within the field is vast. This unique book provides a comprehensive study of the most recent advances in the field and its practical applications.The first part of the book offers the reader an introduction to the basics of artificial cell technology with chapters on its origins, design, current status within medicine and future prospects. Part two covers apoptosis, the use of bone marrow stromal cells in myocardial regeneration together with signalling and tissue engineering. Part three discusses artificial cells for therapy, procedures for various clinical conditions and the current status of the discipline within the field. The book concludes with a final section on the role of artificial cells in medicine with particular focus on the use of artificial cells as blood substitutes and their potential use in myocardial regeneration, drug delivery and in treating kidney and bowel diseases, diabetes and cancer.Artificial cells, cell engineering and therapy is a valuable reference for researchers, students and practitioners within the field. - Introduces the basics of artificial cell technology - Provides a comprehensive study of the most recent advances in artificial cells, cell engineering and cell therapy - Discusses the design, engineering and uses of artificial cells
Precision Medicine For Investigators Practitioners And Providers
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Author : Joel Faintuch
language : en
Publisher: Academic Press
Release Date : 2019-11-16
Precision Medicine For Investigators Practitioners And Providers written by Joel Faintuch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-16 with Science categories.
Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. - Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers - Covers disease groups and ancillary information about techniques, resources and consequences - Follows a structured blueprint, ensuring essential chapters items are not overlooked
Microbial Cell Factories Engineering For Production Of Biomolecules
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Author : Vijai Singh
language : en
Publisher: Academic Press
Release Date : 2021-02-13
Microbial Cell Factories Engineering For Production Of Biomolecules written by Vijai Singh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-13 with Science categories.
Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs
Microbial Biotechnology Integrated Microbial Engineering For B3 Bioenergy Bioremediation And Bioproducts
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Author : Maulin P. Shah
language : en
Publisher: Elsevier
Release Date : 2025-05-15
Microbial Biotechnology Integrated Microbial Engineering For B3 Bioenergy Bioremediation And Bioproducts written by Maulin P. Shah and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-15 with Technology & Engineering categories.
This book highlights the latest advancements in microbial biotechnology and its crucial role in promoting sustainable development across three key areas: bioenergy, bioremediation, and bioproducts.It emphasizes the potential of microbes as renewable, sustainable resources capable of generating high-value products and acting as efficient alternatives to conventional methods. Key topics included algal, bacterial, and fungal biotechnology, focusing on producing biomass and valuable metabolites through CO2 sequestration, concurrent bioremediation, resource recovery, and environmental sustainability. This book presents cutting-edge information on how integrated microbial engineering can valorize waste while sustainably generating essential resources. Additionally, it explores how microbes can help address critical challenges, such as resource depletion and pollution management, offering solutions for a more sustainable future. - Explores cutting-edge technologies in microbial biotechnology, including the production of high-value products using microbes, such as bacteria, fungi, and algae. - Elucidates strategies like mycoremediation, microbial degradation, and integrated CO2 sequestration with bioremediation to address pressing environmental challenges. - Understanding the potential of algae and purple bacteria in waste valorization and circular economy models, including biodiesel production and wastewater treatment. - Provides comprehensive information on the emerging therapeutic possibilities of microbial systems and their role in disease control. - Examines the role of microbes in enhancing plant growth as biofertilizers, contributing to sustainable agricultural practices and improved regional water quality through microbial bioremediation.