Microbial Genomics Challenge Darwin
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Microbial Genomics Challenge Darwin
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Author : Didier Raoult
language : en
Publisher: Frontiers E-books
Release Date :
Microbial Genomics Challenge Darwin written by Didier Raoult and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
The 200th anniversary of Darwin’s birthday was celebrated in 2009, making the concept of Darwinism even more popular than at the time it was originally proposed, to the extent that it has acquired quasi-religious status. His theory revolves around a Tree of Life in which all living organisms are considered to have descended from a single ancestor, and each node represents a common ancestor. It comprises hierarchy and dichotomy, which are typical characteristics of the post-biblical 19th century vision. Indeed, according to post-modern philosophy (also called the French theory) the majority of theories, including scientific ones, are based only on meta-narratives expressing the influence of a culture at a given time. Buddhism or Hinduism may have generated a very different story of evolution. Our way of thinking about life, and the way we describe evolution, have changed radically in the 21st century due to the genomic revolution. Comparative genome analyses have demonstrated that gene repertoires are characterized by plasticity, and there is strong evidence that nearly all genes have been exchanged at some point. Genomic data show that the genetic information of living organisms is inherited not only vertically but also laterally. Lateral gene transfers were at first observed only in bacteria, which contain genes originating from eukaryotes, Archaea and viruses. Such transfers were subsequently identified in all living organisms; giant viruses have chimeric genomes and the human genome is a mosaic of genes with eukaryotic, bacterial, and viral origins. We cannot identify a single common ancestor for the gene repertoire of any organism. Furthermore, a very high proportion of genes have been newly created through gene fusion or degradation, and others show no homology to sequences found in other species. It is now clear that every living organism has a variety of ancestors, while exchanges between species are intense, and the creation of new genes is frequent and permanent in all living organisms. Our current genomic knowledge contradicts the tree of life theory, as established by Darwin. Recent analyses have produced bushes rather than resolved trees, with the structure of some parts remaining elusive. It becomes more and more obvious that phylogenetic relationships are better described by forests and networks and that species evolution looks more like a rhizome. The chimerism and mosaic structure of all living organisms through both non-vertical inheritance and de novo creation can only be assimilated and described by a post-Darwinist concept. In this Research Topic we wish to highlight the influence of microbiology and genomics on our understanding of the complexity of gene repertoires, and also demonstrate how current knowledge does not support Darwin’s theory. Microbiology has offered a great advance in the way we perceive life. Evidence obtained from studies on bacterial and viral evolution, lateral inheritance, phylogenetic trees and biodiversity continues to challenge what constituted, until recently, an unimpeded dogma in biology.
Molecular Mechanisms Of Microbial Evolution
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Author : Pabulo H. Rampelotto
language : en
Publisher: Springer
Release Date : 2018-10-12
Molecular Mechanisms Of Microbial Evolution written by Pabulo H. Rampelotto and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-12 with Science categories.
One of the most profound paradigms that have transformed our understanding about life over the last decades was the acknowledgement that microorganisms play a central role in shaping the past and present environments on Earth and the nature of all life forms. Each organism is the product of its history and all extant life traces back to common ancestors, which were microorganisms. Nowadays, microorganisms represent the vast majority of biodiversity on Earth and have survived nearly 4 billion years of evolutionary change. Microbial evolution occurred and continues to take place in a great variety of environmental conditions. However, we still know little about the processes of evolution as applied to microorganisms and microbial populations. In addition, the molecular mechanisms by which microorganisms communicate/interact with each other and with multicellular organisms remains poorly understood. Such patterns of microbe-host interaction are essential to understand the evolution of microbial symbiosis and pathogenesis.Recent advances in DNA sequencing, high-throughput technologies, and genetic manipulation systems have enabled studies that directly characterize the molecular and genomic bases of evolution, producing data that are making us change our view of the microbial world. The notion that mutations in the coding regions of genomes are, in combination with selective forces, the main contributors to biodiversity needs to be re-examined as evidence accumulates, indicating that many non-coding regions that contain regulatory signals show a high rate of variation even among closely related organisms. Comparative analyses of an increasing number of closely related microbial genomes have yielded exciting insight into the sources of microbial genome variability with respect to gene content, gene order and evolution of genes with unknown functions. Furthermore, laboratory studies (i.e. experimental microbial evolution) are providing fundamental biological insight through direct observation of the evolution process. They not only enable testing evolutionary theory and principles, but also have applications to metabolic engineering and human health. Overall, these studies ranging from viruses to Bacteria to microbial Eukaryotes are illuminating the mechanisms of evolution at a resolution that Darwin, Delbruck and Dobzhansky could barely have imagined. Consequently, it is timely to review and highlight the progress so far as well as discuss what remains unknown and requires future research. This book explores the current state of knowledge on the molecular mechanisms of microbial evolution with a collection of papers written by authors who are leading experts in the field.
Darwin In The Genome
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Author : Lynn Helena Caporale
language : en
Publisher: Darwin in the Genome
Release Date : 2003
Darwin In The Genome written by Lynn Helena Caporale and has been published by Darwin in the Genome this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Business & Economics categories.
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Darwin Devolves
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Author : Michael J. Behe
language : en
Publisher: HarperCollins
Release Date : 2019-02-26
Darwin Devolves written by Michael J. Behe and has been published by HarperCollins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-26 with Religion categories.
The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator. In his controversial bestseller Darwin’s Black Box, biochemist Michael Behe challenged Darwin’s theory of evolution, arguing that science itself has proven that intelligent design is a better explanation for the origin of life. In Darwin Devolves, Behe advances his argument, presenting new research that offers a startling reconsideration of how Darwin’s mechanism works, weakening the theory’s validity even more. A system of natural selection acting on random mutation, evolution can help make something look and act differently. But evolution never creates something organically. Behe contends that Darwinism actually works by a process of devolution—damaging cells in DNA in order to create something new at the lowest biological levels. This is important, he makes clear, because it shows the Darwinian process cannot explain the creation of life itself. “A process that so easily tears down sophisticated machinery is not one which will build complex, functional systems,” he writes. In addition to disputing the methodology of Darwinism and how it conflicts with the concept of creation, Behe reveals that what makes Intelligent Design unique—and right—is that it acknowledges causation. Evolution proposes that organisms living today are descended with modification from organisms that lived in the distant past. But Intelligent Design goes a step further asking, what caused such astounding changes to take place? What is the reason or mechanism for evolution? For Behe, this is what makes Intelligent Design so important.
New Approaches To Prokaryotic Systematics
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Author : Michael Goodfellow
language : en
Publisher: Academic Press
Release Date : 2014-11-24
New Approaches To Prokaryotic Systematics written by Michael Goodfellow and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-24 with Science categories.
Volume 41 of Methods in Microbiology is a methods book designed to highlight procedures that will revitalize the purposes and practices of prokaryotic systematics.This volume will notably show that genomics and computational biology are pivotal to the new direction of travel and will emphasise that new developments need to be built upon historical good practices, notably the continued use of the nomenclatural type concept and the requirement to deposit type strains in at least two service culture collections in different countries. Detailed protocols on cutting edge methods Prepared by leading international experts in the relevant fields
The Tangled Tree
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Author : David Quammen
language : en
Publisher: Simon & Schuster
Release Date : 2019-08-06
The Tangled Tree written by David Quammen and has been published by Simon & Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-06 with Science categories.
In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight percent of the human genome arrived sideways by viral infection—a type of HGT. In The Tangled Tree, “the grandest tale in biology….David Quammen presents the science—and the scientists involved—with patience, candor, and flair” (Nature). We learn about the major players, such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health. “David Quammen proves to be an immensely well-informed guide to a complex story” (The Wall Street Journal). In The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life—including where we humans fit upon it. Thanks to new technologies, we now have the ability to alter even our genetic composition—through sideways insertions, as nature has long been doing. “The Tangled Tree is a source of wonder….Quammen has written a deep and daring intellectual adventure” (The Boston Globe).
Molecular Mechanisms Of Microbial Evolution
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Author : Pabulo H. Rampelotto
language : en
Publisher:
Release Date : 2018
Molecular Mechanisms Of Microbial Evolution written by Pabulo H. Rampelotto and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with SCIENCE categories.
One of the most profound paradigms that have transformed our understanding about life over the last decades was the acknowledgement that microorganisms play a central role in shaping the past and present environments on Earth and the nature of all life forms. Each organism is the product of its history and all extant life traces back to common ancestors, which were microorganisms. Nowadays, microorganisms represent the vast majority of biodiversity on Earth and have survived nearly 4 billion years of evolutionary change. Microbial evolution occurred and continues to take place in a great variety of environmental conditions. However, we still know little about the processes of evolution as applied to microorganisms and microbial populations. In addition, the molecular mechanisms by which microorganisms communicate/interact with each other and with multicellular organisms remains poorly understood. Such patterns of microbe-host interaction are essential to understand the evolution of microbial symbiosis and pathogenesis. Recent advances in DNA sequencing, high-throughput technologies, and genetic manipulation systems have enabled studies that directly characterize the molecular and genomic bases of evolution, producing data that are making us change our view of the microbial world. The notion that mutations in the coding regions of genomes are, in combination with selective forces, the main contributors to biodiversity needs to be re-examined as evidence accumulates, indicating that many non-coding regions that contain regulatory signals show a high rate of variation even among closely related organisms. Comparative analyses of an increasing number of closely related microbial genomes have yielded exciting insight into the sources of microbial genome variability with respect to gene content, gene order and evolution of genes with unknown functions. Furthermore, laboratory studies (i.e. experimental microbial evolution) are providing fundamental biological insight through direct observation of the evolution process. They not only enable testing evolutionary theory and principles, but also have applications to metabolic engineering and human health. Overall, these studies ranging from viruses to Bacteria to microbial Eukaryotes are illuminating the mechanisms of evolution at a resolution that Darwin, Delbruck and Dobzhansky could barely have imagined. Consequently, it is timely to review and highlight the progress so far as well as discuss what remains unknown and requires future research. This book explores the current state of knowledge on the molecular mechanisms of microbial evolution with a collection of papers written by authors who are leading experts in the field.
Microbial Evolution Under Extreme Conditions
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Author : Corien Bakermans
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2015-03-10
Microbial Evolution Under Extreme Conditions written by Corien Bakermans and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-10 with Nature categories.
Today's microorganisms represent the vast majority of biodiversity on Earth and have survived nearly 4 billion years of evolutionary change. However, we still know little about the processes of evolution as applied to microorganisms and microbial populations. Microbial evolution occurred and continues to take place in a vast variety of environmental conditions that range from anoxic to oxic, from hot to cold, from free-living to symbiotic, etc. Some of these physicochemical conditions are considered "extreme", particularly when inhabitants are limited to microorganisms. It is easy to imagine that microbial life in extreme environments is somehow more constrained and perhaps subjected to different evolutionary pressures. But what do we actually know about microbial evolution under extreme conditions and how can we apply that knowledge to other conditions? Appealingly, extreme environments with their relatively limited numbers of inhabitants can serve as good model systems for the study of evolutionary processes. A look at the microbial inhabitants of today's extreme environments provides a snapshot in time of evolution and adaptation to extreme conditions. These adaptations manifest at different levels from established communities and species to genome content and changes in specific genes that result in altered function or gene expression. But as a recent (2011) report from the American Academy of Microbiology observes: "A complex issue in the study of microbial evolution is unraveling the process of evolution from that of adaptation. In many cases, microbes have the capacity to adapt to various environmental changes by changing gene expression or community composition as opposed to having to evolve entirely new capabilities." We have learned much about how microbes are adapted to extreme conditions but relatively little is known about these adaptations evolved. How did the different processes of evolution such as mutation, immigration, horizontal (lateral) gene transfer, recombination, hybridization, genetic drift, fixation, positive and negative selection, and selective screens contribute to the evolution of these genes, genomes, microbial species, communities, and functions? What are typical rates of these processes? How prevalent are each of these processes under different conditions? This book explores the current state of knowledge about microbial evolution under extreme conditions and addresses the following questions: What is known about the processes of microbial evolution (mechanisms, rates, etc.) under extreme conditions? Can this knowledge be applied to other systems and what is the broader relevance? What remains unknown and requires future research? These questions will be addressed from several perspectives including different extreme environments, specific organisms, and specific evolutionary processes.
Progress In Botany
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Author : Ulrich Lüttge
language : en
Publisher: Springer
Release Date : 2014-09-22
Progress In Botany written by Ulrich Lüttge and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-22 with Science categories.
With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on physiology, ecology and vegetation science.
The Comprehensive Guide To Science And Faith
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Author : William A. Dembski
language : en
Publisher: Harvest House Publishers
Release Date : 2021-10-05
The Comprehensive Guide To Science And Faith written by William A. Dembski and has been published by Harvest House Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-05 with Religion categories.
Science and Faith Can—and Do—Support Each Other Science and Christianity are often presented as opposites, when in fact the order of the universe and the complexity of life powerfully testify to intelligent design. With this comprehensive resource that includes the latest research, you’ll witness how the findings of scientists provide compelling reasons to acknowledge the mind and presence of a creator. Featuring more than 45 entries by top-caliber experts, you’ll better understand… how scientific concepts like intelligent design are supported by evidence the scientific findings that support the history and accounts found in the Bible the biases that lead to scientific information being presented as a challenge—rather than a complement—to Christianity Whether you’re looking for answers to your own questions or seeking to explain the case for intelligent design to others, The Comprehensive Guide to Science and Faith is an invaluable apologetic tool that will help you explore and analyze the relevant facts, research, and theories in light of biblical truth.