Darwin In The Genome
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Darwin In The Genome
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Author : Lynn Helena Caporale
language : en
Publisher: Darwin in the Genome
Release Date : 2003
Darwin In The Genome written by Lynn Helena Caporale and has been published by Darwin in the Genome this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Business & Economics categories.
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Microbial Genomics Challenge Darwin
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Author : Didier Raoult
language : en
Publisher: Frontiers E-books
Release Date :
Microbial Genomics Challenge Darwin written by Didier Raoult and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
The 200th anniversary of Darwin’s birthday was celebrated in 2009, making the concept of Darwinism even more popular than at the time it was originally proposed, to the extent that it has acquired quasi-religious status. His theory revolves around a Tree of Life in which all living organisms are considered to have descended from a single ancestor, and each node represents a common ancestor. It comprises hierarchy and dichotomy, which are typical characteristics of the post-biblical 19th century vision. Indeed, according to post-modern philosophy (also called the French theory) the majority of theories, including scientific ones, are based only on meta-narratives expressing the influence of a culture at a given time. Buddhism or Hinduism may have generated a very different story of evolution. Our way of thinking about life, and the way we describe evolution, have changed radically in the 21st century due to the genomic revolution. Comparative genome analyses have demonstrated that gene repertoires are characterized by plasticity, and there is strong evidence that nearly all genes have been exchanged at some point. Genomic data show that the genetic information of living organisms is inherited not only vertically but also laterally. Lateral gene transfers were at first observed only in bacteria, which contain genes originating from eukaryotes, Archaea and viruses. Such transfers were subsequently identified in all living organisms; giant viruses have chimeric genomes and the human genome is a mosaic of genes with eukaryotic, bacterial, and viral origins. We cannot identify a single common ancestor for the gene repertoire of any organism. Furthermore, a very high proportion of genes have been newly created through gene fusion or degradation, and others show no homology to sequences found in other species. It is now clear that every living organism has a variety of ancestors, while exchanges between species are intense, and the creation of new genes is frequent and permanent in all living organisms. Our current genomic knowledge contradicts the tree of life theory, as established by Darwin. Recent analyses have produced bushes rather than resolved trees, with the structure of some parts remaining elusive. It becomes more and more obvious that phylogenetic relationships are better described by forests and networks and that species evolution looks more like a rhizome. The chimerism and mosaic structure of all living organisms through both non-vertical inheritance and de novo creation can only be assimilated and described by a post-Darwinist concept. In this Research Topic we wish to highlight the influence of microbiology and genomics on our understanding of the complexity of gene repertoires, and also demonstrate how current knowledge does not support Darwin’s theory. Microbiology has offered a great advance in the way we perceive life. Evidence obtained from studies on bacterial and viral evolution, lateral inheritance, phylogenetic trees and biodiversity continues to challenge what constituted, until recently, an unimpeded dogma in biology.
In Pursuit Of The Gene
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Author : James Schwartz
language : en
Publisher: Harvard University Press
Release Date : 2010-03-30
In Pursuit Of The Gene written by James Schwartz and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-30 with Science categories.
The mystery of inheritance has captivated thinkers since antiquity, and the unlocking of this mystery—the development of classical genetics—is one of humanity’s greatest achievements. This great scientific and human drama is the story told fully and for the first time in this book. Acclaimed science writer James Schwartz presents the history of genetics through the eyes of a dozen or so central players, beginning with Charles Darwin and ending with Nobel laureate Hermann J. Muller. In tracing the emerging idea of the gene, Schwartz deconstructs many often-told stories that were meant to reflect glory on the participants and finds that the “official” version of discovery often hides a far more complex and illuminating narrative. The discovery of the structure of DNA and the more recent advances in genome science represent the culmination of one hundred years of concentrated inquiry into the nature of the gene. Schwartz’s multifaceted training as a mathematician, geneticist, and writer enables him to provide a remarkably lucid account of the development of the central ideas about heredity, and at the same time bring to life the brilliant and often eccentric individuals who shaped these ideas. In the spirit of the late Stephen Jay Gould, this book offers a thoroughly engaging story about one of the oldest and most controversial fields of scientific inquiry. It offers readers the background they need to understand the latest findings in genetics and those still to come in the search for the genetic basis of complex diseases and traits.
The Intelligent Genome
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Author : Adolf Heschl
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
The Intelligent Genome written by Adolf Heschl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Do our genes determine our behavior? Do humans occupy a unique position in evolution? To clarify these provoking questions, the author takes the reader on an ambitious and entertaining journey through a variety of scientific disciplines. In doing so, he creates an image of human evolution that argues that our entire individual knowledge is determined - to the smallest detail - by phylogeny. A provoking and controversial analysis of the theory of our inability to learn something new and of the extent to which our behavior is determined by our genes.
Darwin S Dna A Brief Introduction To Evolutionary Philosophy
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Author :
language : en
Publisher: MSAC Philosophy Group
Release Date :
Darwin S Dna A Brief Introduction To Evolutionary Philosophy written by and has been published by MSAC Philosophy Group this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Origin Of Species Revisited
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Author : Donald Forsdyke
language : en
Publisher: McGill-Queen's Press - MQUP
Release Date : 2001
Origin Of Species Revisited written by Donald Forsdyke and has been published by McGill-Queen's Press - MQUP this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Literary Criticism categories.
Major inconsistencies in Darwin's theory of the origin of species by natural selection remained unresolved for over a century until the results of recent research in various genome projects led to the theory's reinterpretation. Reviewing this new information, Donald Forsdyke, a laboratory scientist involved in genome research, wondered whether similar discoveries could have been made a century earlier, by one of Darwin's contemporaries. The Origin of Species Revisited describes his investigation into the history of evolutionary biology and its startling conclusion. The trail led first to Joseph Hooker and Thomas Huxley, who had been both the theory's strongest supporters and its most penetrating critics, and eventually to the Victorian George Romanes and Darwin's young research associate William Bateson. Although these men were well-known, their resolution of the origin of species paradox has either been ignored (Romanes), or ignored and reviled (Bateson). Four years after Darwin's death, Romanes published a theory of the origin of species by means of "physiological selection" that resolved the inconsistencies in Darwin's theory and introduced the idea of a "peculiarity" of the reproductive system that allowed selective fertility between "physiological complements." Forsdyke argues that the chemical basis of the origin of species by physiological selection is actually the species-dependent component of the base composition of DNA, showing that Romanes thus anticipated modern biochemistry. Using this new perspective Forsdyke considers some of the outstanding problems in biology and medicine, including the question of how "self" is distinguished from "not-self" by members of different species. Finally he examines the political and ideological forces that led to Romanes' contribution to evolutionary biology remaining unappreciated until now.
Hacking Darwin
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Author : Jamie Metzl
language : en
Publisher: Sourcebooks, Inc.
Release Date : 2019-04-23
Hacking Darwin written by Jamie Metzl and has been published by Sourcebooks, Inc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-23 with Science categories.
"A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril." — Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene A groundbreaking exploration of genetic engineering and its impact on the future of our species from leading geopolitical expert and technology futurist, Jamie Metzl. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race. Enter the laboratories where scientists are turning science fiction into reality. In this captivating and thought-provoking nonfiction science book, Jamie Metzl delves into the ethical, scientific, political, and technological dimensions of genetic engineering, and shares how it will shape the course of human evolution. Cutting-edge insights into the field of genetic engineering and its implications for humanity's future Explores the transformative power of genetic technologies and their potential to reshape human life Examines the ethical considerations surrounding genetic engineering and the choices we face as a species Engaging narrative that delves into the scientific breakthroughs and real-world applications of genetic technologies Provides a balanced perspective on the promises and risks associated with genetic engineering Raises thought-provoking questions about the future of reproduction, human health, and our relationship with nature Drawing on his extensive background in genetics, national security, and foreign policy, Metzl paints a vivid picture of a world where advancements in technology empower us to take control of our own evolution, but also cautions against the pitfalls and ethical dilemmas that could arise if not properly managed. Hacking Darwin is a must-read for anyone interested in the intersection of science, technology, and humanity's future.
Mutation
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Author : Elof Axel Carlson
language : en
Publisher:
Release Date : 2011
Mutation written by Elof Axel Carlson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
The idea of mutation has changed considerably from the pre-Mendelian concepts of Darwin's generation to today's up-to-the-minute genomic context of mutation. The historical approach taken by History of Mutation reveals the way science works, incrementally by small steps rather than by dramatic, and rare, paradigm shifts.
Relics Of Eden
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Author : Daniel J. Fairbanks
language : en
Publisher: Prometheus Books
Release Date : 2009-09-18
Relics Of Eden written by Daniel J. Fairbanks and has been published by Prometheus Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Science categories.
Since the publication in 1859 of Darwin’s Origin of Species, debate over the theory of evolution has been continuous and often impassioned. In recent years, opponents of "Darwin’s dangerous idea" have mounted history’s most sophisticated and generously funded attack, claiming that evolution is "a theory in crisis." Ironically, these claims are being made at a time when the explosion of information from genome projects has revealed the most compelling and overwhelming evidence of evolution ever discovered. Much of the latest evidence of human evolution comes not from our genes, but from so-called "junk DNA," leftover relics of our evolutionary history that make up the vast majority of our DNA. Relics of Eden explores this powerful DNA-based evidence of human evolution. The "relics" are the millions of functionally useless but scientifically informative remnants of our evolutionary ancestry trapped in the DNA of every person on the planet. For example, the analysis of the chimpanzee and Rhesus monkey genomes shows indisputable evidence of the human evolutionary relationship with other primates. Over 95 percent of our genome is identical with that of chimpanzees and we also have a good deal in common with other animal species. Author Daniel J. Fairbanks also discusses what DNA analysis reveals about where humans originated. The diversity of DNA sequences repeatedly confirms the archeological evidence that humans originated in sub-Saharan Africa (the "Eden" of the title) and from there migrated through the Middle East and Asia to Europe, Australia, and the Americas. In conclusion, Fairbanks confronts the supposed dichotomy between evolution and religion, arguing that both science and religion are complementary ways to seek truth. He appeals to the vast majority of Americans who hold religious convictions not to be fooled by the pseudoscience of Creationists and Intelligent Design advocates and to abandon the false dichotomy between religion and real science. This concise, very readable presentation of recent genetic research is completely accessible to the nonspecialist and makes for enlightening and fascinating reading.
The Dynamic Genome
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Author : Antonio Fontdevila
language : en
Publisher: Oxford University Press
Release Date : 2011-06-02
The Dynamic Genome written by Antonio Fontdevila and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-02 with Science categories.
Our ever-increasing knowledge of whole genome sequences is unveiling a variety of structures and mechanisms that impinge on current evolutionary theory. The origin of species, the evolution of form, and the evolutionary impact of transposable elements are just a few of the many processes that have been revolutionised by ongoing genome studies. These novelties, among others, are examined in this book in relation to their general significance for evolution, emphasising their human relevance. The predominance of non-coding DNA in the human genome, the long-term adaptive role of so called "junk DNA" in the evolution of new functions, and the key evolutionary differences that define our humanity are just some of the controversial issues that this book examines in the context of Darwinian evolution. The author's principle intention is to show that whilst genomics is revealing new and previously unanticipated mechanisms and sources of variability that must be incorporated into evolutionary theory, there is no reason to dismiss the role of natural selection as the mechanism that sorts out these potentialities. In other words, this genome potential provides new possibilities (and also constraints) for evolution, but the realization of this potential is driven by natural selection.