The Dynamic Genome
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The Dynamic Genome
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Author : Antonio Fontdevila
language : en
Publisher: Oxford University Press
Release Date : 2011-06-02
The Dynamic Genome written by Antonio Fontdevila and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-02 with Science categories.
These novelties, among others, are examined in this book in relation to their general significance for evolution, emphasising their human relevance.
The Dynamic Genome
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Author : Nina Vsevolod Fedoroff
language : en
Publisher: CSHL Press
Release Date : 1992
The Dynamic Genome written by Nina Vsevolod Fedoroff and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Biography & Autobiography categories.
"But at Cold Spring Harbor, she began the studies on the consequence of dicentric chromosome formation and breakage that led her to the discovery of genetic elements capable moving within the genome and controlling expression of other genes. Although McClintock was universally respected and admired, the first reaction to these findings was often uncomprehending or indifferent, even dismissive. In due course, however, the generality of mobile genetic elements and the concept of a dynamic genome were understood and widely accepted, culminating in the award to McClintock of an unshared Nobel prize in 1983." "As Barbara's 90th birthday approached, some of her many friends and colleagues were invited to write essays for the occasion. This book contains a kaleidoscope of contributions, many by those who discovered transposition in other organisms. Their essays give a remarkable account of the scientific legacy of one of the century's greatest geneticists."--BOOK JACKET.
Transposons And The Dynamic Genome
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Author : Dirk-Henner Lankenau
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-30
Transposons And The Dynamic Genome written by Dirk-Henner Lankenau and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-30 with Science categories.
This volume gives an overview on mobile DNA and how such contradiction to the obligatory stability of genomes can be understood. Obviously, an understanding can only be achieved by cutting deeply into the evolutionary history of life.
The Dynamic Genome And Mental Health
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Author : Kenneth S. Kendler
language : en
Publisher: OUP USA
Release Date : 2011-05-26
The Dynamic Genome And Mental Health written by Kenneth S. Kendler and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-26 with Psychology categories.
This volume contains the latest theories and evidence about the highly dynamic inter-relation between genes and environments as they influence the development, mental health and substance use of adolescents.
The Dynamic Bacterial Genome
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Author : Peter Mullany
language : en
Publisher: Cambridge University Press
Release Date : 2010-02-04
The Dynamic Bacterial Genome written by Peter Mullany and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-04 with Science categories.
The genetic information contained in DNA is not static, especially in bacterial DNA. It is capable of recombining with other DNA sequences and transferring to other bacteria. These processes allow bacteria to rapidly respond to their environment and are also important in production of disease and the spread of antibiotic resistance. This book is concerned with the mechanisms underlying these dynamic processes in bacterial DNA.
Genes
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Author : Benjamin Lewin
language : en
Publisher: John Wiley & Sons
Release Date : 1985
Genes written by Benjamin Lewin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Science categories.
Cells obey the laws of physics and chemistry; DNA as a store of information; Genes are metable units; DNA is the genetic material; The topology of nucleic acids; Isolating the gene; Turning genes into proteins; The assembly line for protein sysnthesis; Transfer RNA: the translational adaptor; The ribosome translation factory; The messenger RNA templlate; Controlling gene expression by transcription; RNA polymerase-promoter interactions control initiation; A panoply of operons: the lactose paradigm and others; Control at termination: attenuation and antitermination; Lytic cascades and lysogenic repression; Perpetuation of DNA; The replicon: unit of replication; The apparatus for DNA replication; Systems that safeguard DNA; Constitution of the eukaryotic genome; The extraordinary power of DNA technology; A continuum of sequences includes structural genes; The organization of interrupted genes; Clusters of relates sequences; Structural genes belond to families of various sizes; Genomes sequestered in organelles; Organization of simple sequence DNA; Reachiong maturity: RNA processing; Cutting and trimming stable RNA; RNNA as catalyst: mechanisms of splicing; Control of RNA processing; The packaging of DNA; About genomes and chromosomes; Chromatin structure: the nucleosome; The nature of active chromatin; The dynamic genome: DNA in flux; Recombination and other topological manipulations of DNA; Transposable elements in bacteria; Mobile elements in eukaryotes; Enginnering changes in the genome; Genes in development; Rearrangements and the generation of immune diversity; Changing gene organization from within and without; Gene regulation: changing patterns of expression; Oncogenes: aberrant gene expression and cancer; Landmark changes in perspectives.
Subtelomeres
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Author : Edward J Louis
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-18
Subtelomeres written by Edward J Louis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-18 with Science categories.
New genes and diversity leading to adaptation and evolution are generated in special areas of genomes. One such area in all eukaryotic genomes and in those prokaryotes with linear chromosomes is the region near the ends of the chromosomes. These telomere-associated sequences or subtelomeres, have different properties than the rest of the genome and are one of the most exciting frontiers left in genomics. This book provides a broad introduction to the field of subtelomeres with detailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomes. Advances in the field as well as continuing challenges are discussed throughout. The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves. Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions. The dynamic nature of the region and the ability to change the copy number, generate diversity and try novel combinations make it the evolutionary tinker’s toolbox. In many organisms the genes found in the region are involved in dealing with the environment. In yeasts, different gene families involved in sugar metabolism as well as clumping together are found in subtelomeres and differences in the region may be the reason why some strains are good for baking, others for brewing and why some are pathogenic. In fungal plant and animal pathogens, many of the genes involved in virulence are found here. In humans and primates there are a number of gene families that vary between ends, for example the diverse olfactory receptor genes. Even in bacterial linear chromosomes the region contains genes involved in adapting to their environments. Perhaps the ultimate use of these regions is in parasites where they rapidly adapt and escape from host immune systems through dynamic changes to the proteins exposed to the host’s defenses. Such dynamic, polymorphic structures are also found in plants and insects though it is not always clear what the function might be; in some cases they take on the role of end maintenance. The dynamic, polymorphic nature of subtelomeres, where many ends share segmental duplications, is an exciting area for study but also presents a difficult challenge from the technical perspective.
Structure And Function Of The Bacterial Genome
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Author : Charles J. Dorman
language : en
Publisher: John Wiley & Sons
Release Date : 2020-02-04
Structure And Function Of The Bacterial Genome written by Charles J. Dorman and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-04 with Science categories.
Presents an integrated view of the expression of bacterial genetic information, genome architecture and function, and bacterial physiology and pathogenesis This book blends information from the very latest research on bacterial chromosome and nucleoid architecture, whole-genome analysis, cell signaling, and gene expression control with well-known gene regulation paradigms from model organisms (including pathogens) to give readers a picture of how information flows from the environment to the gene, modulating its expression and influencing the competitive fitness of the microbe. Structure and Function of the Bacterial Genome explores the governance of the expression of the genes that make a bacterium what it is, and updates the basics of gene expression control with information about transcription promoter structure and function, the role of DNA as a regulatory factor (in addition to its role as a carrier of genetic information), small RNAs, RNAs that sense chemical signals, ribosomes and translation, posttranslational modification of proteins, and protein secretion. It looks at the forces driving the conservation and the evolution of the dynamic genome and offers chapters that cover DNA replication, DNA repair, plasmid biology, recombination, transposition, the roles of repetitive DNA sequences, horizontal gene transfer, the defense of the genome by CRISPR-Cas, restriction enzymes, Argonaute proteins and BREX systems. The book finishes with a chapter that gives an integrated overview of genome structure and function. Blends knowledge of gene regulatory mechanisms with a consideration of nucleoid structure and dynamics Offers a 'DNA-centric' approach to considering transcription control Views horizontal gene transfer from a gene regulation perspective Assesses the opportunities and limitations of designing synthetic microbes or rewiring existing ones Structure and Function of the Bacterial Genome is an ideal book for graduate and undergraduate students studying microbial cell biology, bacterial pathogenesis, gene regulation, and molecular microbiology. It will also appeal to principal investigators conducting research on these and related topics and researchers in synthetic biology and other arms of biotechnology.
Genes Five
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Author : Benjamin Lewin
language : en
Publisher:
Release Date : 1994
Genes Five written by Benjamin Lewin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Genetics categories.
Cells as macromolecular assemblies; DNA as a store of information; Translation: expressing genes as proteins; Constructing the cell; Control of prokaryotic gene expression; Perpetuation of DNA; Organization of the eukaryotic genome; Eukaryotic transcription and RNA processing; The dynamic genome: DNA in flux; Genes in development.
The Dynamic Bacterial Genome
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Author : Peter Mullany
language : en
Publisher:
Release Date : 2005
The Dynamic Bacterial Genome written by Peter Mullany and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Bacterial genetics categories.
This book is concerned with the mechanisms underlying recombination in bacterial DNA.