Microenvironment Derived Stem Cell Plasticity
DOWNLOAD
Download Microenvironment Derived Stem Cell Plasticity PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Microenvironment Derived Stem Cell Plasticity book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Microenvironment Derived Stem Cell Plasticity
DOWNLOAD
Author : Jelena Krstic
language : en
Publisher: Frontiers Media SA
Release Date : 2017-12-21
Microenvironment Derived Stem Cell Plasticity written by Jelena Krstic and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-21 with Electronic book categories.
Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions, but also metabolic and mechanical cues. Such dynamic and specialized microenvironment where the stem cells reside is considered a stem cell niche. Tissue injury as well as malignant tissue alterations lead to changes in the niche influencing the plasticity and biology of residing stem cells. Similarly, the niche changes upon tissue damage, which eventually induces differentiation of stem cells and ultimately regeneration of the tissue.
Microenvironment Derived Stem Cell Plasticity
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2017
Microenvironment Derived Stem Cell Plasticity written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions, but also metabolic and mechanical cues. Such dynamic and specialized microenvironment where the stem cells reside is considered a stem cell niche. Tissue injury as well as malignant tissue alterations lead to changes in the niche influencing the plasticity and biology of residing stem cells. Similarly, the niche changes upon tissue damage, which eventually induces differentiation of stem cells and ultimately regeneration of the tissue.
Adult Stem Cells
DOWNLOAD
Author : Kursad Turksen
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-01-27
Adult Stem Cells written by Kursad Turksen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-27 with Science categories.
Studies on stem cells have been attracting intense scientific and p- lic attention, not only because of controversies surrounding the use of embryonic stem cells but also because of very provocative data that have been emerging on adult stem cells. Much of the public attention and debate has been focused on the possibility that adult stem cells may be used as a substitute for human embryonic stem cells or as a justification for stopping work on them. This has somewhat dim- ished attention on very heated scientific debates that take us to the very heart of how the concept of stem cells is perceived. To this author, the latter debates have not been unlike certain philosophical debates of the last century. Since the seminal studies of Till and McCulloch in the 1960s, the popular paradigm on adult stem cells has been that lineage-restricted stem cells are derived from pluripotent stem cells very early during development. To many, and consistent with much data, the restriction to particular lineages was considered absolute. In other words, there was a sense of determinism in the stem quality of particular stem cells: once they were allocated, they were programmed to specific roles in a given tissue. Furthermore, some adult tissues were considered devoid of detectable stem cell presence or activity.
The Stem Cell Microenvironment And Its Role In Regenerative Medicine And Cancer Pathogenesis
DOWNLOAD
Author : Cristian Pablo Pennisi
language : en
Publisher: River Publishers
Release Date : 2016-12-05
The Stem Cell Microenvironment And Its Role In Regenerative Medicine And Cancer Pathogenesis written by Cristian Pablo Pennisi and has been published by River Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-05 with Medical categories.
How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able not only to mechanically support cells, but also to release signals biologically relevant for governing stem cell fate. In addition, increasing evidence suggests that abnormal interaction of stem cells with their niche is responsible for altered cell function leading to malignant transformation. This book discusses some of the recent advances in stem cell research that may help understanding the properties of the niche that govern stem cell fate. Technical topics discussed include: Stem cell biologyCancer stem cellsStem cell interactions with biomaterialsEngineering the stem cell microenvironmentStem cells in tissue regeneration and repair The Disputationes Workshop series is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. This book emerges as a result of the scientific contributions presented and discussed during the fifth Disputationes Workshop held in Aalborg (Denmark) in April 2014. The stem cell microenvironment and its role in regenerative medicine and cancer pathogenesis is ideal for academic staff and master/research students in biomedical and health sciences
Stem Cell Bioengineering And Tissue Engineering Microenvironment
DOWNLOAD
Author : Satya Prakash
language : en
Publisher: World Scientific
Release Date : 2011
Stem Cell Bioengineering And Tissue Engineering Microenvironment written by Satya Prakash and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
This is a comprehensive review of the current state of stem cell bioengineering from authorities in the field. The first part of the book includes the basic research work on stem cells and bioengineering carried out by various laboratories. The second part consists of a review of the current development of various microcapsules in stem cell therapy. The last part will summarize the overall clinical trials on stem cell therapy and myocardial regeneration as well as the most updated personal experience recently completed by well-known experts in this field.
Stem Cell Plasticity
DOWNLOAD
Author : Suraksha Agrawal
language : en
Publisher: Nova Science Pub Incorporated
Release Date : 2009-01-01
Stem Cell Plasticity written by Suraksha Agrawal and has been published by Nova Science Pub Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-01 with Medical categories.
Although hematopoetic stem cell (HSC) transplantation has been in practice for almost half a century, the improved understanding of stem cells over past two decades has revolutionised this field making it as most promising aspect of translational medicine. HSC are found in small numbers in peripheral blood as compared to bone marrow. However, use of growth factors has opened new avenues to successfully use peripheral blood as source of CD 34+ HSC. These are pluripotent cells that are competent for self renewal and differentiation to a variety of specialised cells and are replenished with fresh cells every day. Recent understanding about their mobilisation, homing and plasticity suggest that they can be useful for the maintenance and regeneration of various specialised tissues. This provides an opportunity to explore the specific niche responsible for stem cell plasticity, their trans-differentiation into specific cellular lineages as well the kinetics of their recovery whenever required. The normal physiological microenvironment may be unable to provide a suitable environment for the rapid regeneration of HSC required for coping with tissue damage and may need some external interventions. The autologous stem-cell transplantation (SCT), has decreased risk of graft -- versus -- host disease, and provides opportunities of external interventions in terms of ex vivo manipulation. In the diseases of hematopoietic and immune system allogeneic transplant remains a better modality but is associated with grave risk of graft -- versus -- host disease (GVHD). However, in these cases it is needed to engineer the hematopoietic stem cell (HSC) graft to remove the cells which cause GVHD or relapse to improve graft functions. Hematopoetic stem cell transplantations have been successful in a variety of diseases including leukemia and other hematopoetic disorders. Though results of HSCT are promising, developing a more mechanistic approach to plasticity and improving the external interventions and ex vivo manipulations may lead to improving the efficiency and speed of regeneration of transplanted cells. This could result in better use and wider application of stem cell based therapies.
Adult Stem Cell Therapies Alternatives To Plasticity
DOWNLOAD
Author : Mariusz Z. Ratajczak
language : en
Publisher: Springer
Release Date : 2014-09-10
Adult Stem Cell Therapies Alternatives To Plasticity written by Mariusz Z. Ratajczak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-10 with Science categories.
This timely volume explores various techniques for tissue and organ regeneration using stem cells isolated from adult tissues. It discusses alternative explanations of stem cell plasticity as well as current clinical results with adult stem cell therapies. It examines the presence of potential pluripotent stem cells in adult tissues, paracrine effects of stem cell therapies, and involvement of exosomes and microparticles into observed phenomena. Fifteen chapters, all written by noted leaders of their fields, focus on a variety of topics including cord blood and hematopoietic stem cells, skin and tissue organ regeneration, very small embryonic-like stem cells, and cell therapies in cardiology, neonatology, and neurology. Edited by Dr. Mariusz Ratajczak, an internationally known specialist in adult stem cell biology, Adult Stem Cell Therapies: Alternatives to Plasticity is an important addition to the Stem Cell Biology and Regenerative Medicine series.
Biology Of Stem Cells And The Molecular Basis Of The Stem State
DOWNLOAD
Author : Dov Zipori
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-01
Biology Of Stem Cells And The Molecular Basis Of The Stem State written by Dov Zipori and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-01 with Science categories.
Biology of Stem Cells and the Molecular Basis of the Stem State concentrates upon adult stem cells, particularly on mesenchymal cell populations, which is the author’s area of expertise. The text offers the reader a detailed description of the emergence of stem cell research and the dogmas that were created during the first decades of analysis of stem cell properties, particularly those of hemopoietic stem cells. Biology of Stem Cells and the Molecular Basis of the Stem State also introduces the reader to the commonly accepted notions regarding stem cell biology, with an emphasis on an alternative view of stemness, i.e. the stem state. In keeping with the popularity of this topic, Biology of Stem Cells and the Molecular Basis of the Stem State addresses the major controversies and points of dispute, among researchers in the stem cell field. Overall, Biology of Stem Cells and the Molecular Basis of the Stem State presents a well-rounded dialogue about stem cells as it not only concentrates upon the biological elements of stem cell, but also addresses the controversy and hype currently enveloping this popular subject.
An Assessment Of Stem Cell Plasticity
DOWNLOAD
Author : Akiva J. Marcus
language : en
Publisher:
Release Date : 2007
An Assessment Of Stem Cell Plasticity written by Akiva J. Marcus and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Stem Cell Plasticity
DOWNLOAD
Author : Suraksha Agrawal
language : en
Publisher:
Release Date : 2009
Stem Cell Plasticity written by Suraksha Agrawal and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Hematopoietic stem cells categories.