Microfluidics Enabled Interfacial Capacitive Sensors For Biomedical Applications
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Microfluidics Enabled Interfacial Capacitive Sensors For Biomedical Applications
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Author : Baoqing Nie
language : en
Publisher:
Release Date : 2015
Microfluidics Enabled Interfacial Capacitive Sensors For Biomedical Applications written by Baoqing Nie and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Pressure is a vital indicator in various physiological systems. Therefore, extracting the pressure information (e.g., intraocular pressure, intracranial pressure) becomes important in monitoring these physiological systems. A variety of pressure sensors/transducers have been investigated and most of them rely on resistive, piezoelectric, or capacitive sensing mechanism. However, several major challenges preventing their adoption in advanced medical devices (e.g., surgical instruments) are the needs for high sensitivity, accuracy, fast mechanical response, and high flexibility. In this dissertation, we have introduced a novel microfluidics-enabled interfacial capacitive sensor, referred to as MICS, with ultrahigh pressure sensitivity and resolution, fast mechanical response, and skin-like flexibility at a low-cost for various biomedical applications. Utilizing a high-capacitance electrical double layer (EDL) at the elastic electrode-electrolyte interface, the MICS with a simple device architecture achieves an ultra-large capacitance and an ultrahigh device sensitivity, i.e. more than 1,000 times larger than the traditional solid-state capacitive sensors. Importantly, the influences of the design parameters on the device sensitivity have been thoroughly investigated, as the desired device sensitivity can vary considerably for different applications. In addition, utilizing the low-viscosity sensing liquids on a hydrophobic-modified surface, we have been able to achieve high-frequency responses to external stimuli (up to 1kHz). Moreover, benefiting from the chemical and thermal stability of the sensing liquids, we have largely removed the concerns of environmental sensitivities (e.g., evaporation) and achieved stable sensing units. Furthermore, the simple device architecture -- the entire device consists of only two flexible micropatterned electrode layers and one spacing layer, allows us to massively produce the MICS at low-cost yet high reliability. Besides the investigations on the device performances, we have also explored a multi-functional MICS. Inspired by the physiological tactile sensation, we have successfully devised the MICS to detect the normal and shear pressure as well as to map surface topology at an ultrafine spatial resolution (greater than that of human skin) within a flexible and transparent package. In addition, the MICS has been developed into a wireless pressure sensor, allowing it to be integrated in implantable and remote sensing devices. As demonstrations, we have applied the wireless MICS, encapsulated in a biocompatible silicone rubber, to monitor the intraocular pressure of human eyes. In Vitro tests have been performed, in which the sensor achieves a good sensitivity and accuracy within the target pressure range. In addition, we have devised the MICS in a miniaturized package (0.20mm x 0.16mm x 1.50mm) with an ultrahigh capacitive output. Given its high sensitivity and miniaturized design, this MICS can be readily integrated into existing medical devices (e.g., guide wires) for an invasive physiological pressure monitoring. In conclusion, a novel interfacial capacitive sensing principle is presented in this dissertation, and we believe this novel sensing approach will offer a highly transformative solution to various medical applications (e.g., diagnoses of glaucoma and coronary artery disease) in the near future.
Cmos Capacitive Sensors For Lab On Chip Applications
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Author : Ebrahim Ghafar-Zadeh
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10
Cmos Capacitive Sensors For Lab On Chip Applications written by Ebrahim Ghafar-Zadeh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Technology & Engineering categories.
1.1 Overview of Lab-on-Chip Laboratory-on-Chip (LoC) is a multidisciplinary approach used for the miniaturization, integration and automation of biological assays or procedures in analytical chemistry [1–3]. Biology and chemistry are experimental sciences that are continuing to evolve and develop new protocols. Each protocol offers step-by-step laboratory instructions, lists of the necessary equipments and required biological and/or chemical substances [4–7]. A biological or chemical laboratory contains various pieces of equipment used for performing such protocols and, as shown in Fig. 1.1, the engineering aspect of LoC design is aiming to embed all these components in a single chip for single-purpose applications. 1.1.1 Main Objectives of LoC Systems Several clear advantages of this technology over conventional approaches, including portability, full automation, ease of operation, low sample consumption and fast assays time, make LoC suitable for many applications including. 1.1.1.1 Highly Throughput Screening To conduct an experiment, a researcher fills a well with the required biological or chemical analytes and keeps the sample in an incubator for some time to allowing the sample to react properly. Afterwards, any changes can be observed using a microscope. In order to quickly conduct millions of biochemical or pharmacolo- cal tests, the researchers will require an automated highly throughput screening (HTS) [8], comprised of a large array of wells, liquid handling devices (e.g., mic- channel, micropump and microvalves [9–11]), a fully controllable incubator and an integrated sensor array, along with the appropriate readout system.
Frontiers In Robotics And Ai Editor S Picks 2022
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Author : Kostas J. Kyriakopoulos
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-10
Frontiers In Robotics And Ai Editor S Picks 2022 written by Kostas J. Kyriakopoulos and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-10 with Science categories.
Soft Material Enabled Electronics For Medicine Healthcare And Human Machine Interfaces
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Author : Jae-Woong Jeong
language : en
Publisher: MDPI
Release Date : 2020-03-13
Soft Material Enabled Electronics For Medicine Healthcare And Human Machine Interfaces written by Jae-Woong Jeong and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-13 with Technology & Engineering categories.
Soft material-enabled electronics offer distinct advantage, over conventional rigid and bulky devices, for numerous wearable and implantable applications. Soft materials allow for seamless integration with skin and tissues due to enhanced mechanical flexibility and stretchability. Wearable devices, such as sensors, offer continuous, real-time monitoring of biosignals and movements, which can be applied in rehabilitation and diagnostics, among other applications. Soft implantable electronics offer similar functionalities, but with improved compatibility with human tissues. Biodegradable soft implantable electronics are also being developed for transient monitoring, such as in the weeks following surgery. To further advance soft electronics, materials, integration strategies, and fabrication techniques are being developed. This paper reviews recent progress in these areas, toward the development of soft material-enabled electronics for medicine, healthcare, and human-machine interfaces.
Solid State Sensors Actuators And Microsystems Workshop 2010
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Author :
language : en
Publisher:
Release Date : 2010
Solid State Sensors Actuators And Microsystems Workshop 2010 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Actuators categories.
Driving Smart Medical Diagnosis Through Ai Powered Technologies And Applications
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Author : Khang, Alex
language : en
Publisher: IGI Global
Release Date : 2024-02-26
Driving Smart Medical Diagnosis Through Ai Powered Technologies And Applications written by Khang, Alex and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-26 with Medical categories.
Academic scholars face the daunting challenge of keeping pace with the rapid evolution of innovative technologies. The emergence of AI-driven solutions, deep learning frameworks, and medical robotics introduces a complex terrain, demanding in-depth understanding and analysis. As scholars navigate the intricacies of patient hate speech detection, cardiovascular diseases AI-CDSS, and the revolution in medical diagnostics, a pressing need arises for comprehensive insights that bridge the gap between theoretical knowledge and practical applications. Driving Smart Medical Diagnosis Through AI-Powered Technologies and Applications serves as a solution in this era of transformative healthcare and addresses these challenges head-on. It unravels the complexities surrounding the implementation of AI in healthcare, offering in-depth discussions on the latest breakthroughs. From unraveling the mysteries of AI-driven cataract detection to exploring the implications of decentralized mammography classification, the book is a valuable resource that equips scholars with the knowledge to navigate this innovative landscape.
Smart 3d Nanoprinting
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Author : Ajit Behera
language : en
Publisher: CRC Press
Release Date : 2022-08-18
Smart 3d Nanoprinting written by Ajit Behera and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-18 with Technology & Engineering categories.
Examining smart 3D printing at the nanoscale, this book discusses various methods of fabrication, the presence of inherent defects and their annihilation, property analysis, and emerging applications across an array of industries. The book serves to bridge the gap between the concept of nanotechnology and the tailorable properties of smart 3D-print products. FEATURES Covers surface and interface analysis and smart technologies in 3D nanoprinting Details different materials, such as polymers, metals, semiconductors, glassceramics, and composites, as well as their selection criteria, fabrication, and defect analysis at nanoscale Describes optimization and modeling and the effect of machine parameters on 3D-printed products Discusses critical barriers and opportunities Explores emerging applications in manufacturing industries, such as aerospace, healthcare, automotive, energy, construction, and defense Smart 3D Nanoprinting: Fundamentals, Materials, and Applications is aimed at advanced students, researchers, and industry professionals in materials, manufacturing, chemical, and mechanical engineering. This book offers readers a comprehensive overview of the properties, opportunities, and applications of smart 3D nanoprinting.
Advances In Nano And Biochemistry
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Author : Pranay Pradeep Morajkar
language : en
Publisher: Elsevier
Release Date : 2023-05-23
Advances In Nano And Biochemistry written by Pranay Pradeep Morajkar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-23 with Science categories.
Advances in Nano and Biochemistry: Environmental and Biomedical Applications gives insights into this advanced interdisciplinary science that encompasses the principles of physics and physical chemistry for the investigation of various processes and problems in biological systems. The book is a concise culmination of biophysical chemistry knowledge acquired through core concepts and advanced technologies for addressing emerging challenges in environmental and biomedical applications. Sections cover early diagnostic techniques and accurate treatment strategies using bioinspired, sustainable technologies, including nanomaterials, nanoenzymes, biopolymers, electrochemical biomolecule sensors, biocompatible magnetic nanomaterials, quantum dots and hybrid structures, and DNA nanotechnology. Other sections discuss advanced technologies for sensing and remedying environmental pollutants, including but not limited to, photocatalytic oxidations, gum polysaccharides based nanostructured materials, bio-inspired and biocompatible nanomaterials, hydrogel nanocomposites, and contemporary enzymes and nanozymes based technologies. Ultimately, the state-of-the-art chapters in this book will empower researchers to combine two complementary elements - chemical analysis use and biomedical applications. - Provides the fundamental concepts of biophysical chemistry and emerging technologies to solve environmental and biomedical problems - Describes the latest breakthrough research in biophysical chemistry and its applications to better understand biological systems - Supports development of the latest disease diagnostic and treatment technologies - Includes advances in physical chemistry and biology for the monitoring and remediation of environmental pollutants
Antenna And Sensor Technologies In Modern Medical Applications
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Author : Yahya Rahmat-Samii
language : en
Publisher: John Wiley & Sons
Release Date : 2021-02-25
Antenna And Sensor Technologies In Modern Medical Applications written by Yahya Rahmat-Samii and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-25 with Technology & Engineering categories.
A guide to the theory and recent development in the medical use of antenna technology Antenna and Sensor Technologies in Modern Medical Applications offers a comprehensive review of the theoretical background, design, and the latest developments in the application of antenna technology. Written by two experts in the field, the book presents the most recent research in the burgeoning field of wireless medical telemetry and sensing that covers both wearable and implantable antenna and sensor technologies. The authors review the integrated devices that include various types of sensors wired within a wearable garment that can be paired with external devices. The text covers important developments in sensor-integrated clothing that are synonymous with athletic apparel with built-in electronics. Information on implantable devices is also covered. The book explores technologies that utilize both inductive coupling and far field propagation. These include minimally invasive microwave ablation antennas, wireless targeted drug delivery, and much more. This important book: Covers recent developments in wireless medical telemetry Reviews the theory and design of in vitro/in vivo testing Explores emerging technologies in 2D and 3D printing of antenna/sensor fabrication Includes a chapter with an annotated list of the most comprehensive and important references in the field Written for students of engineering and antenna and sensor engineers, Antenna and Sensor Technologies in Modern Medical Applications is an essential guide to understanding human body interaction with antennas and sensors.
Ionic Liquid Devices
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Author : Ali Eftekhari
language : en
Publisher: Royal Society of Chemistry
Release Date : 2017-09-14
Ionic Liquid Devices written by Ali Eftekhari and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-14 with Technology & Engineering categories.
Ionic liquids are attractive because they offer versatility in the design of organic salts. As ion-rich media, ionic liquids can control the systems properties by tuning the size, charge, and shape of the composing ions. Whilst the focus has mainly been on the potential applications of ionic liquids as solvents, they also provide innovative opportunities for designing new systems and devices. Limitations from the high viscosity and expensive purification of the ionic liquids are also not a barrier for applications as devices. Written by leading authors, Ionic Liquid Devices introduces the innovative applications of ionic liquids. Whilst the first chapters focus on their characterization, which can be difficult in some instances, the rest of the book demonstrates how ionic liquids can play substantial roles in quite different systems from sensors and actuators to biomedical applications. The book provides a comprehensive resource aimed at researchers and students in materials science, polymer science, chemistry and physics interested in the materials and inspire the discovery of new applications of ionic liquids in smart devices.