Microneedle Mediated Transdermal And Intradermal Drug Delivery
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Microneedle Mediated Transdermal And Intradermal Drug Delivery
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Author : Ryan F. Donnelly
language : en
Publisher: John Wiley & Sons
Release Date : 2012-01-17
Microneedle Mediated Transdermal And Intradermal Drug Delivery written by Ryan F. Donnelly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-17 with Medical categories.
Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.
Microneedles For Drug And Vaccine Delivery And Patient Monitoring
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Author : Ryan F. Donnelly
language : en
Publisher: John Wiley & Sons
Release Date : 2018-08-20
Microneedles For Drug And Vaccine Delivery And Patient Monitoring written by Ryan F. Donnelly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-20 with Science categories.
Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications. Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry. The only book currently available on microneedles Filled with tables, graphs, and black and white images (photographs, micrographs) Authored by four experts in pharmaceutics Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.
Microneedles
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Author : Kevin Ita
language : en
Publisher: Academic Press
Release Date : 2022-02-06
Microneedles written by Kevin Ita and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-06 with Medical categories.
Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery. As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study. Provides information for the design and fabrication of microneedles Discusses choice of materials, fabrication protocol, sterilization protocol and characterization Supplies the most up-to-date research on all aspects of microneedles
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery
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Author : Ryan F. Donnelly
language : en
Publisher: John Wiley & Sons
Release Date : 2015-09-28
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery written by Ryan F. Donnelly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-28 with Science categories.
This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.
Microneedles
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Author : Hiep Xuan Nguyen
language : en
Publisher: CRC Press
Release Date : 2023-07-04
Microneedles written by Hiep Xuan Nguyen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-04 with Technology & Engineering categories.
The microneedle field has been expanding exponentially with innovative designs and various applications, thus capturing the interest of academic industry and regulatory sectors. Microneedles: The Future of Drug Delivery equips readers with a comprehensive understanding of microneedles: from percutaneous absorption to microneedles production, characterization, applications in drug delivery and diagnosis, to practical perspectives on the development, manufacturing, regulatory issues, and commercialization of microneedles. This book is written by a single author and thus provides complex information in a simple, elegant, and cohesive style. The book is intended for graduate students, researchers, scientists, and engineers working in the pharmaceutical, medical, cosmeceutical, and biotechnology industry.
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery
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Author : Ryan F. Donnelly
language : en
Publisher: John Wiley & Sons
Release Date : 2015-08-07
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery written by Ryan F. Donnelly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-07 with Science categories.
This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery
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Author : Ryan F. Donnelly
language : en
Publisher: Wiley
Release Date : 2015-08-18
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery written by Ryan F. Donnelly and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-18 with Science categories.
Microneedles For Transdermal Drug Delivery
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Author : Jaspreet Singh Kochhar
language : en
Publisher: Springer
Release Date : 2019-07-04
Microneedles For Transdermal Drug Delivery written by Jaspreet Singh Kochhar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-04 with Medical categories.
This monograph covers a novel technology to deliver drugs and cosmetics through the skin in a minimally invasive manner. Microneedles – a bed of miniaturized needles is one of the most studied topics in delivering actives through the skin barrier. This book enables readers to understand the delivery of ingredients through the skin, describes a novel and simple method to fabricate microneedles containing a range of small and large molecular weight compounds, studies their physical properties as well as delivery through the skin layers. Readers will discover this book to be extremely beneficial to help them understand the state of the field of transdermal drug delivery, with extensive coverage including experimental data on basics of microneedle fabrication technology using photolithography, encapsulation of drugs within the polymeric matrix of microneedles and studying their release patternsin vitro and ex vivo . Academic researchers, pharmaceutical and cosmeceutical industry as well as students of skin science will find this account very useful in their pursuits. As microneedles grow and develop into a commercial reality with more actives being delivered and significant clinical research being put in, this account will hold well in providing basic principles and knowledge together with rigorous experimental data.
Imaging Technologies And Transdermal Delivery In Skin Disorders
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Author : Chenjie Xu
language : en
Publisher: John Wiley & Sons
Release Date : 2020-03-09
Imaging Technologies And Transdermal Delivery In Skin Disorders written by Chenjie Xu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-09 with Science categories.
Provides the latest information on imaging technologies and transdermal delivery in skin disorders This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. It also places great emphasis on the critical role that interdisciplinary science occupies to achieve the requisite level of understanding of skin conditions and their management, which is essential to creating technologies that work. Imaging Technologies and Transdermal Delivery in Skin Disorders starts by outlining the structural characteristics of skin and skin appendages. It then discusses the key pathways involved in skin growth and development. Clinical presentations, pathophysiological mechanisms, and current clinical practices used to treat diseases affecting the skin are then introduced. Common preclinical models used for studying the mechanisms of diverse skin diseases, validation of novel therapeutic targets, and screening of new drugs to treat these diseases are also covered. The book examines the latest imaging technologies for understanding in vivo skin changes, as well as technologies such as high-resolution ultrasound imaging, quantitative Magnetic Resonance Imaging, high-resolution Optical Coherence Tomography, and emerging hybrid-imaging modalities. It concludes with chapters introducing emerging drug delivery technologies and potential future innovative developments. * Presents up-to-date knowledge of the skin biology and pathologies * Introduces advancements in the topic of imaging technology for tracing the drug delivery process, which is rarely systematically reported by other counterparts * Covers the latest development in three inter-related directions of drug delivery, imaging, and skin disease intersect for skin research * Provides an overview of the latest development of diagnostic and therapeutic technologies for skin diseases Imaging Technologies and Transdermal Delivery in Skin Disorders will be of great interest to analytical chemists, materials scientists, pharmaceutical chemists, clinical chemists, biotechnologists, bioengineers, cosmetics industry, and dermatologists.
Transdermal And Intradermal Delivery Of Therapeutic Agents
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Author : Ajay K Banga
language : en
Publisher: CRC Press
Release Date : 2011-05-16
Transdermal And Intradermal Delivery Of Therapeutic Agents written by Ajay K Banga and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-16 with Medical categories.
Skin, once thought to be an impenetrable barrier, is an extremely active organ capable of interacting with its environment. Advancements in science combined with the need for diverse drug delivery modalities have introduced a variety of transdermal and intradermal products for existing drugs at a fraction of the cost of new drug development. Commer