Microneedles
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Microneedles For Transdermal Drug Delivery
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Author : Jaspreet Singh Kochhar
language : en
Publisher: Springer
Release Date : 2019-07-04
Microneedles For Transdermal Drug Delivery written by Jaspreet Singh Kochhar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-04 with Medical categories.
This monograph covers a novel technology to deliver drugs and cosmetics through the skin in a minimally invasive manner. Microneedles – a bed of miniaturized needles is one of the most studied topics in delivering actives through the skin barrier. This book enables readers to understand the delivery of ingredients through the skin, describes a novel and simple method to fabricate microneedles containing a range of small and large molecular weight compounds, studies their physical properties as well as delivery through the skin layers. Readers will discover this book to be extremely beneficial to help them understand the state of the field of transdermal drug delivery, with extensive coverage including experimental data on basics of microneedle fabrication technology using photolithography, encapsulation of drugs within the polymeric matrix of microneedles and studying their release patternsin vitro and ex vivo . Academic researchers, pharmaceutical and cosmeceutical industry as well as students of skin science will find this account very useful in their pursuits. As microneedles grow and develop into a commercial reality with more actives being delivered and significant clinical research being put in, this account will hold well in providing basic principles and knowledge together with rigorous experimental data.
Microneedles For Drug And Vaccine Delivery And Patient Monitoring
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Author : Ryan F. Donnelly
language : en
Publisher: John Wiley & Sons
Release Date : 2018-08-20
Microneedles For Drug And Vaccine Delivery And Patient Monitoring written by Ryan F. Donnelly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-20 with Science categories.
Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications. Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry. The only book currently available on microneedles Filled with tables, graphs, and black and white images (photographs, micrographs) Authored by four experts in pharmaceutics Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.
Microneedles
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Author : Kevin Ita
language : en
Publisher: Academic Press
Release Date : 2022-02-06
Microneedles written by Kevin Ita and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-06 with Medical categories.
Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery. As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study. Provides information for the design and fabrication of microneedles Discusses choice of materials, fabrication protocol, sterilization protocol and characterization Supplies the most up-to-date research on all aspects of microneedles
Design And Applications Of Microneedles In Drug Delivery And Therapeutics
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Author : Prashant Kesharwani
language : en
Publisher: Elsevier
Release Date : 2024-07-01
Design And Applications Of Microneedles In Drug Delivery And Therapeutics written by Prashant Kesharwani and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-01 with Science categories.
Microneedles in Drug Delivery and Therapeutics details the design, characterization and applications of this novel drug delivery system.Microneedles offer several advantages over traditional oral and parenteral approaches, due to their ability to be fabricated and altered in shape, size and material type, matched to specific treatment needs.This book covers the materials selection, design and fabrication approaches, and clinical translation of microneedles for a range of therapeutic applications, including: cancer therapy, gene and vaccine delivery, wound healing and more. Microneedles in Drug Delivery and Therapeutics is a forward-thinking resource for those working in the development of materials and devices for novel drug delivery. Introduces the reader to skin anatomy and materials development in regard to microneedles as smart carriers for drug delivery, offering an interdisciplinary approach that will appeal to a wide audience Covers a broad range of therapeutic applications, from ocular diseases and photodynamic therapy to sensing and cancer treatment Provides an overview of the materials, design, fabrication, clinical translation, commercial aspects of microneedle development, and their applications in drug delivery
Microneedles
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Author : Hiep Xuan Nguyen
language : en
Publisher: CRC Press
Release Date : 2023-07-04
Microneedles written by Hiep Xuan Nguyen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-04 with Technology & Engineering categories.
The microneedle field has been expanding exponentially with innovative designs and various applications, thus capturing the interest of academic industry and regulatory sectors. Microneedles: The Future of Drug Delivery equips readers with a comprehensive understanding of microneedles: from percutaneous absorption to microneedles production, characterization, applications in drug delivery and diagnosis, to practical perspectives on the development, manufacturing, regulatory issues, and commercialization of microneedles. This book is written by a single author and thus provides complex information in a simple, elegant, and cohesive style. The book is intended for graduate students, researchers, scientists, and engineers working in the pharmaceutical, medical, cosmeceutical, and biotechnology industry.
Microneedle Mediated Transdermal And Intradermal Drug Delivery
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Author : Ryan F. Donnelly
language : en
Publisher: John Wiley & Sons
Release Date : 2012-01-17
Microneedle Mediated Transdermal And Intradermal Drug Delivery written by Ryan F. Donnelly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-17 with Medical categories.
Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.
Microneedling In Clinical Practice
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Author : Boris Stoeber
language : en
Publisher: CRC Press
Release Date : 2020-10-01
Microneedling In Clinical Practice written by Boris Stoeber and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-01 with Health & Fitness categories.
Microneedles provide an artificial pathway across the skin barrier for medical and cosmetic applications. This technology has seen a significant increase in popularity over the past years; as an example, the use of multiple small needles mounted on a roller to pierce the skin, prompting it to stimulate collagen production, has undergone a resurgence of interest as an adjunctive procedure for a number of skin disorders. This monograph draws together what is known about how to integrate microneedle technology into clinical dermatologic practice.
Microneedle Drug Delivery System
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Author : Dr. Manish Kumar
language : en
Publisher: Lulu.com
Release Date :
Microneedle Drug Delivery System written by Dr. Manish Kumar and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Polymer Microneedles For Transdermal Delivery Of Biopharmaceuticals
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Author : Sean Padraic Sullivan
language : en
Publisher:
Release Date : 2009
Polymer Microneedles For Transdermal Delivery Of Biopharmaceuticals written by Sean Padraic Sullivan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Mems Based Transdermal Drug Delivery
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Author : Richa Mishra
language : en
Publisher: CRC Press
Release Date : 2023-12-11
Mems Based Transdermal Drug Delivery written by Richa Mishra and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-11 with Technology & Engineering categories.
This book introduces transdermal drug delivery and the developments that have taken place in various transdermal drug delivery techniques including the system-level design approach of a novel miniaturized medical device to offer precise and painless drug delivery via a skin-based transdermal route. It discusses the microelectromechanical systems (MEMS)-based fabrication technique and the design, fabrication and characterization of different MEMS-based components like microneedles and micropumps. It further includes a MEMS-based component micropump with design, analysis, fabrication and characterization of the transdermal drug delivery device and challenges encountered in the design improvements. Features: Summarizes transdermal drug delivery systems especially with a focus on MEMS and microneedles, including theoretical concepts Emphasizes system integration by describing simulation and design techniques as well as experimental fabrication Discusses system-level integration for miniaturized therapeutic devices Includes working simulation models covering microneedles and micropump analysis Explores future direction in development of pertinent devices. The book is aimed at researchers, professionals, and graduate students in biomedical engineering, microelectronics, micro-electro-mechanical-systems, and drug delivery.