Micrornas In Health And Disease
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Micrornas In Health And Disease
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Author : Milena Rizzo
language : en
Publisher:
Release Date : 2024-04-29
Micrornas In Health And Disease written by Milena Rizzo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-29 with Science categories.
This Special Issue delves into the intricate world of miRNAs as modulators of gene expression regulation. These small non-coding RNAs are at the heart of post-transcriptional modulation of gene activity, affecting a myriad of biological processes. The curated selection of articles within this issue offers insights into the roles of miRNAs in health and disease, emphasizing their potential value as therapeutic targets and biomarkers. Featuring original research and in depth-reviews, this Special Issue covers recent miRNA advancements, detailing their regulatory networks and action mechanisms. It highlights new miRNA-linked therapeutic targets and circulating miRNAs as cell-to-cell communication intermediaries. The issue also examines extracellular miRNAs (ex-miRNAs) and their functions, highlighting their presence in biological fluids and their potential utility in clinical diagnostics and disease monitoring. Challenges in miRNA quantification and technological advances for precise measurement are also discussed. The issue traverses the less-charted territories of miRNA research, such as the discovery of small nucleolar-derived miRNAs and the elucidation of transposable elements as unexpected constituents of the miRNA regulatory network. Overall, this collection showcases the evolving nature of miRNA research, offering valuable perspectives for future scientific inquiry and medical innovation. It reflects the drive to decode gene regulation complexities, providing insights for health professionals and researchers at the forefront of gene regulation research.
Microrna
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Author : Jaishree Paul
language : en
Publisher: CRC Press
Release Date : 2018-02-19
Microrna written by Jaishree Paul and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-19 with Medical categories.
This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology.
Microrna Regulation In Health And Disease
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Author : Clifford J. Steer
language : en
Publisher: MDPI
Release Date : 2020-02-21
Microrna Regulation In Health And Disease written by Clifford J. Steer and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-21 with Science categories.
MicroRNAs (miRNAs) are small regulatory RNAs that play a crucial role in posttranscriptional gene regulation. Over two thousand miRNAs have been identified in humans, and many of them are conserved in other species. miRNAs are implicated in fundamental cellular functions, including development and disease. In the last decade, there has been an overwhelming amount of data contributing to the understanding of miRNA biogenesis and their target genes. Moreover, a significant amount of work has been carried out in developing miRNA biomarkers and therapeutics for various disease conditions. RNA-based markers and therapeutics have been proven to have a clinical impact, and many of these miRNA-based therapies are at various stages of human clinical trials and clinical applications. Notably, miRNAs are also found in exosomes, and are considered to impart intercellular communication and function via several different modalities, including tunneling nanotubes. In spite of our understanding of miRNA biology and function, there are many challenges in effectively using miRNAs as biomarkers and therapeutic agents in clinical applications. In this Special Issue, we are inviting reviews, perspectives, and original research articles to address some of these challenges. Topics will include, but are not limited to, miRNA biogenesis, clinical applications, extracellular function, biomarkers, miRNA immune regulation, signaling pathways, and preclinical models.
Microrna
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Author : Jaishree Paul
language : en
Publisher: CRC Press
Release Date : 2018
Microrna written by Jaishree Paul and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with MicroRNA categories.
"A CRC title, part of the Taylor & Francis imprint, a member of the Taylor & Francis Group, the academic division of T&F Informa plc."
Microrna Regulation In Health And Disease
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Author : Clifford Steer
language : en
Publisher:
Release Date : 2020
Microrna Regulation In Health And Disease written by Clifford Steer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Biology (General) categories.
MicroRNAs (miRNAs) are small regulatory RNAs that play a crucial role in posttranscriptional gene regulation. Over two thousand miRNAs have been identified in humans, and many of them are conserved in other species. miRNAs are implicated in fundamental cellular functions, including development and disease. In the last decade, there has been an overwhelming amount of data contributing to the understanding of miRNA biogenesis and their target genes. Moreover, a significant amount of work has been carried out in developing miRNA biomarkers and therapeutics for various disease conditions. RNA-based markers and therapeutics have been proven to have a clinical impact, and many of these miRNA-based therapies are at various stages of human clinical trials and clinical applications. Notably, miRNAs are also found in exosomes, and are considered to impart intercellular communication and function via several different modalities, including tunneling nanotubes. In spite of our understanding of miRNA biology and function, there are many challenges in effectively using miRNAs as biomarkers and therapeutic agents in clinical applications. In this Special Issue, we are inviting reviews, perspectives, and original research articles to address some of these challenges. Topics will include, but are not limited to, miRNA biogenesis, clinical applications, extracellular function, biomarkers, miRNA immune regulation, signaling pathways, and preclinical models.
Micrornas In Diseases And Disorders Emerging Therapeutic Targets
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Author : Philip V Peplow
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-05-21
Micrornas In Diseases And Disorders Emerging Therapeutic Targets written by Philip V Peplow and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-21 with Medical categories.
From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.
Micrornas In Medicine
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Author : Charles H. Lawrie
language : en
Publisher: John Wiley & Sons
Release Date : 2013-10-30
Micrornas In Medicine written by Charles H. Lawrie and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-30 with Science categories.
MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics. Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research.
Mirnas Human Health And Diseases
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Author : Luis M. Vaschetto
language : en
Publisher: Springer
Release Date : 2024-09-22
Mirnas Human Health And Diseases written by Luis M. Vaschetto and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-22 with Science categories.
This new volume of the book series Epigenetics and Human Health is dedicated to microRNAs (miRNAS), regulatory non-coding RNAs that have important roles in the control of gene expression both at posttranscriptional and transcriptional levels. Endogenous miRNAs regulate gene expression patterns in a sequence-specific manner. These short sequences may serve as potential therapeutic targets in the treatment of complex diseases including cancer, cardiovascular diseases, neurocognitive disorders, respiratory diseases and pathogenic infections. Moreover, miRNAs hold promise to be used as extensive diagnostic and prognostic markers of disease. miRNAs, Human Health and Disease is an essential reading for graduate and undergraduate students, researchers, and academics interested in the latest developments on non-coding RNA-mediated pathways associated with health and disease.
Nutrigenomics And Proteomics In Health And Disease
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Author : Martin Kussmann
language : en
Publisher: John Wiley & Sons
Release Date : 2017-05-08
Nutrigenomics And Proteomics In Health And Disease written by Martin Kussmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-08 with Technology & Engineering categories.
Now in a revised second edition, Nutrigenomics and Proteomics in Health and Disease brings together the very latest science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals and their impact on gene interaction and health. Authored by an international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date. Thoroughly updated to reflect the most current developments in the field, the second edition includes six new chapters covering gut health and the personal microbiome; gut microbe-derived bioactive metabolites; proteomics and peptidomics in nutrition; gene selection for nutrigenomic studies; gene-nutrient network analysis, and nutrigenomics to nutritional systems biology. An additional five chapters have also been significantly remodelled. The new text includes a rethinking of in vitro and in vivo models with regard to their translatability into human phenotypes, and normative science methods and approaches have been complemented by more comprehensive systems biology-based investigations, deploying a multitude of omic platforms in an integrated fashion. Innovative tools and methods for statistical treatment and biological network analysis are also now included.
Macro Roles For Micrornas In The Life And Death Of Neurons
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Author : Bart De Strooper
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-01
Macro Roles For Micrornas In The Life And Death Of Neurons written by Bart De Strooper and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-01 with Medical categories.
The discovery of microRNAs has revealed an additional level of fine tuning of the genome and how genes are used again and again in different combinations to generate the complexity that underlies for instance the brain. This book examines this field.