Mitochondrial Function And Biogenesis
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Mitochondrial Function And Biogenesis
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Author : Carla Koehler
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-05-13
Mitochondrial Function And Biogenesis written by Carla Koehler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-05-13 with Medical categories.
This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level. (Cover)
Mitochondrial Function And Biogenesis
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Author : Carla Koehler
language : en
Publisher: Springer
Release Date : 2014-10-08
Mitochondrial Function And Biogenesis written by Carla Koehler and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-08 with Science categories.
Mitochondria are complex organelles, possessing a double-membrane and even their own genome, the mtDNA. They play a pivotal role in cellular metabolism, respiration, and production of ATP essential for the normal function of all human organ systems. It is not surprising, therefore, that genetic defects of mitochondrial functions cause a wide spectrum of human diseases. This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level. The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome evolution and mtDNA stability, mitochondrial biogenesis and protein quality control, mitochondrial morphology, assembly and function of the mitochondrial energy generation apparatus and mitochondrial metabolic pathways. These are particularly oriented to link in these various mitochondrial pathways to the clinical consequences of their dysfunctions.
Mitochondria In Higher Plants
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Author : Roland Douce
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Mitochondria In Higher Plants written by Roland Douce and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.
Mitochondria in Higher Plants: Structure, Function, and Biogenesis is a collection and interpretation of information on plant mitochondria. It explains not only the basic enzymology of ATP synthesis coupled to electron transport that seems to constitute the major activity of the mitochondria, but also many other aspects that make plant mitochondria rather more diverse than their animal counterparts. Organized into five chapters, this book begins with the morphological and cytological observations on mitochondria, and proceeding through membrane and matrix functions to participation in metabolism and biogenesis. Each section presents the unique properties of plant mitochondria within the framework of general mitochondrial structure and function. This book is intended not only for research workers and students interested in the enzymology of plant mitochondria respiration, but also for graduate and undergraduate students in the field of plant biochemistry, cell physiology, and molecular biology. It will be useful as a starting point for those students wishing to pursue special studies in this field.
Mitochondrial Biogenesis And Genetics
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Author : Giuseppe Attardi
language : en
Publisher: Elsevier
Release Date : 1995
Mitochondrial Biogenesis And Genetics written by Giuseppe Attardi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Biological transport categories.
The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 250 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * Structural and functional analysis of oxidative phosphorylation complexes * Import of proteins and RNA into mitochondria * Ion and metabolite transport systems in mitochondria * Biophysical methods for mitochondrial function analysis * Mitochondrial inheritance and turnover.
Mitochondrial Biogenesis And Genetics Part B
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Author : Giuseppe M. Attardi
language : en
Publisher: Academic Press
Release Date : 1996-03-08
Mitochondrial Biogenesis And Genetics Part B written by Giuseppe M. Attardi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-03-08 with Nature categories.
The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 260 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * This volume covers methodology used in * Mitochondrial gene expression * Mitochondrial genetics and gene manipulation * Mitochondrial diseases and aging
Mitochondria Structure Biogenesis And Transducing Functions
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Author : H. Tedeschi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mitochondria Structure Biogenesis And Transducing Functions written by H. Tedeschi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the past few years, the body of experimental work on the structure, function and assembly processes of mitochondria has expanded rapidly. No one person can believe himself or herself completely in control of the burgeoning literature without possessing serious omissions or blind spots. In the present monograph I have attempted a critical evaluation of the literature. I believe that the common thread of single authorship outweighs the shortcomings of one person presenting many disparate viewpo,ints. It is my hope that the end product represents a comprehensive and coordinated review of the subject matter to the present date. Although the bulk of this monograph was completed by October 1974, I have made some attempts to update several of the sections at later times. Albany, N. Y. , November 1975 H. TEDESCHI Contents A. Structure of Mitochondria 1. General Organization . a) Conventional Thin Section Electron Microscopy b) Negative Staining Techniques . 3 c) Freeze-Cleavage . . . . . . . 4 2. Special Organization and Inclusions 10 a) Prismatic or Atypical Cristae 10 b) Filaments and Tubules . . 11 c) Amorphous Inclusions 12 d) Intramitochondrial Granules 12 e) DNA Containing Fibers 14 3. Topography of the Mitochondrial Transducing Systems 15 B. The Assembly of Mitochondria 18 1. Mitochondrial DNA and Its Genetic Role 19 2. Transcription of the Mitochondrial DNA . 28 a) mRNA . . . . . . . . . . . . . . 30 b) The Machinery for Transcription and Translation 32 c) Turnover of Mitochondrial RNA 36 3. Protein Synthesis . . . . . . . . 37 a) Mitochondrial Protein Synthesis and Its Characteristics 37 b) Role of Mitochondrial Protein Synthesis . .
Mitochondria
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Author :
language : en
Publisher: Elsevier
Release Date : 2001-05-23
Mitochondria written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-23 with Science categories.
This title employs biochemical, cell biological, and genetic approaches to study mitochondrial structure, function, and biogenesis. Also of interest are the consequences of impaired mitochondrial function on cells, tissues, and organs. The book is full of step-by-step "how to" methods with sample results, interpretations, and pitfalls. There is a unique set of appendices that include gene catalogs, mtDNA maps, and reagents for probing respiratory chain function. Finally, there are applications of state-of-the art microarray and gene chip technologies. Isolation of mitochondria from commonly used cells and tissues Assays for mitochondrial activities, including respiration, ATP production, permeability, protein import, and interactions with the cytoskeleton Biochemical and optical methods for studying protein-protein interactions in mitochondria Approaches to studying mitochondrial replication, transcription, and translation Transmitochondrial technologies Methods in microassay data analysis
Mitochondrial Biogenesis And Genetics Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 1995-11-07
Mitochondrial Biogenesis And Genetics Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-11-07 with Science categories.
The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 250 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * Structural and functional analysis of oxidative phosphorylation complexes * Import of proteins and RNA into mitochondria * Ion and metabolite transport systems in mitochondria * Biophysical methods for mitochondrial function analysis * Mitochondrial inheritance and turnover
Mitochondrial Function In Lung Health And Disease
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Author : Viswanathan Natarajan
language : en
Publisher: Springer
Release Date : 2014-07-26
Mitochondrial Function In Lung Health And Disease written by Viswanathan Natarajan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-26 with Medical categories.
Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.
Mitochondria In Health And Disease
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Author : Paolo Bernardi
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-01
Mitochondria In Health And Disease written by Paolo Bernardi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-01 with Science categories.
Mitochondrial biology reinvented itself and became a new world that has attracted new scientists influencing every field of biomedical research. Mitochondrial research is growing and changing, as reflected by the exponential rise in the number of conferences covering mitochondrial biology and the role of mitochondria in diseases ranging from neurodegenerative diseases,metabolic diseases and genetic muscular dystrophies toimmunopathologies and cancer. As the awareness of the essential role of mitochondria in pathology rose, a demand for new approaches to measure mitochondrial function resulted in the robust development of new forms of microscopy and spectroscopy that opened windows into previously unknown aspects of mitochondrial biology. Two Conferences provided an outstanding representation of this state of affairs, the Gordon Research Conference Mitochondrial Dynamics and Signaling (Ventura, California March 17-22, 2019) and the FASEB Conference Mitochondrial Biogenesis and Dynamics in Health and Disease (Palm Springs, California May 19-24, 2019). These conferences well reflected the explosion of the field of mitochondrial communication within the cell, between cells and across organs, as well as the budding of a new field on the definition of individual mitochondria and the identification of subtypes with diverse structural features that may serve different specific functions. Through our participation in these meetings, we conceived the idea to cover some of these topics in the Research Topic “Mitochondria in Health and Disease” of Frontiers in Physiology - Mitochondrial Research Specialty Section. Fitting the tradition of Frontiers, our contributors have generated a platform incuding both solid data and new concepts, as radical and courageous as they can be. We are pleased with the outcome and we hope that our readers will share our enthusiasm.