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Modeling And Simulating Cardiac Electrical Activity

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Modeling And Simulating Cardiac Electrical Activity

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Author : Trine Krogh-Madsen
language : en
Publisher: IOP Publishing Limited
Release Date : 2020-12-03

Modeling And Simulating Cardiac Electrical Activity written by Trine Krogh-Madsen and has been published by IOP Publishing Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-03 with Science categories.

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialized researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Key Features Thorough introduction to the topic of mathematical modeling of electrical activity in the heart Focuses on use of experimental data in mathematical modeling, and on explanations rather than equations In addition to being experts in the field, the contributing authors are expert science communicators

Modeling And Simulating Cardiac Electrical Activity

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Author : Trine Krogh-Madsen
language : en
Publisher: Myprint
Release Date : 2020-12-03

Modeling And Simulating Cardiac Electrical Activity written by Trine Krogh-Madsen and has been published by Myprint this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-03 with categories.

Mathematically Modelling The Electrical Activity Of The Heart From Cell To Body Surface And Back Again

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Author : Andrew Pullan
language : en
Publisher: World Scientific Publishing Company
Release Date : 2005-09-07

Mathematically Modelling The Electrical Activity Of The Heart From Cell To Body Surface And Back Again written by Andrew Pullan and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-07 with Science categories.

This book on modelling the electrical activity of the heart is an attempt to describe continuum based modelling of cardiac electrical activity from the cell level to the body surface (the forward problem), and back again (the inverse problem). Background anatomy and physiology is covered briefly to provide a suitable context for understanding the detailed modelling that is presented herein. The questions of what is mathematical modelling and why one would want to use mathematical modelling are addressed to give some perspective to the philosophy behind our approach. Our view of mathematical modelling is broad — it is not simply about obtaining a solution to a set of mathematical equations, but includes some material on aspects such as experimental and clinical validation.

Cardiovascular Computing Methodologies And Clinical Applications

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Author : Spyretta Golemati
language : en
Publisher: Springer
Release Date : 2019-02-12

Cardiovascular Computing Methodologies And Clinical Applications written by Spyretta Golemati and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-12 with Technology & Engineering categories.

This book provides a comprehensive guide to the state-of-the-art in cardiovascular computing and highlights novel directions and challenges in this constantly evolving multidisciplinary field. The topics covered span a wide range of methods and clinical applications of cardiovascular computing, including advanced technologies for the acquisition and analysis of signals and images, cardiovascular informatics, and mathematical and computational modeling.

Mathematically Modelling The Electrical Activity Of The Heart

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Author : Andrew J. Pullan
language : en
Publisher: World Scientific
Release Date : 2005

Mathematically Modelling The Electrical Activity Of The Heart written by Andrew J. Pullan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.

This book on modelling the electrical activity of the heart is an attempt to describe continuum based modelling of cardiac electrical activity from the cell level to the body surface (the forward problem), and back again (the inverse problem). Background anatomy and physiology is covered briefly to provide a suitable context for understanding the detailed modelling that is presented herein. The questions of what is mathematical modelling and why one would want to use mathematical modelling are addressed to give some perspective to the philosophy behind our approach. Our view of mathematical modelling is broad ? it is not simply about obtaining a solution to a set of mathematical equations, but includes some material on aspects such as experimental and clinical validation.

Modeling And Simulation Theory And Practice

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Author : George A. Bekey
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Modeling And Simulation Theory And Practice written by George A. Bekey and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Modeling and Simulation: Theory and Practice provides a comprehensive review of both methodologies and applications of simulation and modeling. The methodology section includes such topics as the philosophy of simulation, inverse problems in simulation, simulation model compilers, treatment of ill-defined systems, and a survey of simulation languages. The application section covers a wide range of topics, including applications to environmental management, biology and medicine, neural networks, collaborative visualization and intelligent interfaces. The book consists of 13 invited chapters written by former colleagues and students of Professor Karplus. Also included are several short 'reminiscences' describing Professor Karplus' impact on the professional careers of former colleagues and students who worked closely with him over the years.

Sensing Modeling And Optimization Of Cardiac Systems

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Author : Hui Yang
language : en
Publisher: Springer Nature
Release Date : 2023-08-18

Sensing Modeling And Optimization Of Cardiac Systems written by Hui Yang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-18 with Business & Economics categories.

This book reviews the development of physics-based modeling and sensor-based data fusion for optimizing medical decision making in connection with spatiotemporal cardiovascular disease processes. To improve cardiac care services and patients’ quality of life, it is very important to detect heart diseases early and optimize medical decision making. This book introduces recent research advances in machine learning, physics-based modeling, and simulation optimization to fully exploit medical data and promote the data-driven and simulation-guided diagnosis and treatment of heart disease. Specifically, it focuses on three major topics: computer modeling of cardiovascular systems, physiological signal processing for disease diagnostics and prognostics, and simulation optimization in medical decision making. It provides a comprehensive overview of recent advances in personalized cardiac modeling by integrating physics-based knowledge of the cardiovascular system with machine learning and multi-source medical data. It also discusses the state-of-the-art in electrocardiogram (ECG) signal processing for the identification of disease-altered cardiac dynamics. Lastly, it introduces readers to the early steps of optimal decision making based on the integration of sensor-based learning and simulation optimization in the context of cardiac surgeries. This book will be of interest to researchers and scholars in the fields of biomedical engineering, systems engineering and operations research, as well as professionals working in the medical sciences.

Computational Modeling And Simulation Examples In Bioengineering

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Author : Nenad Filipovic
language : en
Publisher: John Wiley & Sons
Release Date : 2021-12-14

Computational Modeling And Simulation Examples In Bioengineering written by Nenad Filipovic and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-14 with Science categories.

A systematic overview of the quickly developing field of bioengineering—with state-of-the-art modeling software! Computational Modeling and Simulation Examples in Bioengineering provides a comprehensive introduction to the emerging field of bioengineering. It provides the theoretical background necessary to simulating pathological conditions in the bones, muscles, cardiovascular tissue, and cancers, as well as lung and vertigo disease. The methodological approaches used for simulations include the finite element, dissipative particle dynamics, and lattice Boltzman. The text includes access to a state-of-the-art software package for simulating the theoretical problems. In this way, the book enhances the reader's learning capabilities in the field of biomedical engineering. The aim of this book is to provide concrete examples of applied modeling in biomedical engineering. Examples in a wide range of areas equip the reader with a foundation of knowledge regarding which problems can be modeled with which numerical methods. With more practical examples and more online software support than any competing text, this book organizes the field of computational bioengineering into an accessible and thorough introduction. Computational Modeling and Simulation Examples in Bioengineering: Includes a state-of-the-art software package enabling readers to engage in hands-on modeling of the examples in the book Provides a background on continuum and discrete modeling, along with equations and derivations for three key numerical methods Considers examples in the modeling of bones, skeletal muscles, cartilage, tissue engineering, blood flow, plaque, and more Explores stent deployment modeling as well as stent design and optimization techniques Generates different examples of fracture fixation with respect to the advantages in medical practice applications Computational Modeling and Simulation Examples in Bioengineering is an excellent textbook for students of bioengineering, as well as a support for basic and clinical research. Medical doctors and other clinical professionals will also benefit from this resource and guide to the latest modeling techniques.

Computing The Electrical Activity In The Heart

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Author : Joakim Sundnes
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-26

Computing The Electrical Activity In The Heart written by Joakim Sundnes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-26 with Mathematics categories.

The heart is a fantastic machine; during a normal lifetime it beats about 2.5 billion times and pumps 200.000 tons of blood through an enormous system of vessels extending 160.000 kilometres throughout the body. For centuries, man has tried to understand how the heart works, but there remain many unsolved problems, problems that have captured the attention of thousands of researchers worldwide. There is, for example, a huge amount of research being devoted to the analysis of single heart cells. Other areas of research include trying to understand how it works as a complete muscle, and how blood ows through the heart. The entire process is extremely complex. The history of bioelectricity can be traced back to the late eighteenth century and the experiments of Luigi Galvani. A century later, in 1887, Augustus Wallers managed to measure the electrical signal generated by the heart at the surface of the body [142]. His dog Jimmy earned a place in history by being the rst to have his heart measured in this way; see Figure 1.1. In 1903 Willem Einthoven [34] - veloped the rst commercial device for recording electrocardiograms (ECGs); see Figure 1.2.

Simulation And Imaging Of The Cardiac System

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Author : S. Sideman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Simulation And Imaging Of The Cardiac System written by S. Sideman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

The ultrasound velocity tomography allows measurement of cardiac geometries for various phases in the cardiac cycle. The present tomograph makes reconstruc tions at intervals of 20 ms. Because of a lack of clear (intramural) landmarks (except the roots of the papillairy muscle), it is difficult to pinpoint spatial trajectories of particular points in the heart. Therefore, a second method was developed of injecting radiopaque markers in the heart and following their motion patterns during the cardiac cycle with help of a biplane X-ray equipment. The data obtained with both methods can be implemented in our finite element model of the heart to compute intramural stresses and strains. The results obtained sofar with the extended Darcy equation to account for the interaction of blood rheology and tissue mechanics look promising. Further testing with more sophisticated subjects than mentioned in Figure 9 is required before it will be implemented in our finite element model of the heart. We conclude that analysis of regional cardiac function, including regional myocardial blood flow, requires still a major research effort but the results obtained sofar justify, to our opinion, a continuation in this direction. Acknowledgement The authors acknowledge Dr. C. Borst and coworkers for doing the animal experiments and prof. Van Campen and dr. Grootenboer for their participation is some aspects of this work.

Modeling And Simulating Cardiac Electrical Activity

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