Modeling Of Nanotoxicity
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Modeling Of Nanotoxicity
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Author : Ruhong Zhou
language : en
Publisher: Springer
Release Date : 2015-09-04
Modeling Of Nanotoxicity written by Ruhong Zhou and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-04 with Technology & Engineering categories.
This book provides a comprehensive overview of the fundamentals of nanotoxicity modeling and its implications for the development of novel nanomedicines. It lays out the fundamentals of nanotoxicity modeling for an array of nanomaterial systems, ranging from carbon-based nanoparticles to noble metals, metal oxides, and quantum dots. The author illustrates how molecular (classical mechanics) and atomic (quantum mechanics) modeling approaches can be applied to bolster our understanding of many important aspects of this critical nanotoxicity issue. Each chapter is organized by types of nanomaterials for practicality, making this an ideal book for senior undergraduate students, graduate students, and researchers in nanotechnology, chemistry, physics, molecular biology, and computer science. It is also of interest to academic and industry professionals who work on nanodrug delivery and related biomedical applications, and aids readers in their biocompatibility assessment efforts in the coming age of nanotechnology. This book also provides a critical assessment of advanced molecular modeling and other computational techniques to nanosafety, and highlights current and future biomedical applications of nanoparticles in relation to nanosafety.
Nanotoxicity
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Author : Saura C. Sahu
language : en
Publisher: John Wiley & Sons
Release Date : 2009-08-04
Nanotoxicity written by Saura C. Sahu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-04 with Science categories.
Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials. Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include: biomarkers for nanotoxicity assessment nanotoxicity assessment by gene expression analysis in vivo and in vitro models for nanotoxicity testing mechanisms of nanotoxicity pharmakokinetics of nanomaterials nanotoxicity of foods including food processing, food packaging and food safety nanotoxicity of drugs including drug development and drug delivery nanotoxicity of cosmetics and consumer products health and environmental impact of nanotoxicity safety evaluation of nanomaterials regulatory impact of nanomaterials Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.
Nanotoxicology
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Author : Alok Dhawan
language : en
Publisher: Royal Society of Chemistry
Release Date : 2017-11-13
Nanotoxicology written by Alok Dhawan and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-13 with Medical categories.
This book fills the significant nanotoxicology and nanosafety knowledge gaps and covers a broad range of topics. It targets postgraduates, academics, and practicing industrialists.
Nanotechnology In Medicine
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Author : Mahendra Rai
language : en
Publisher: John Wiley & Sons
Release Date : 2021-10-19
Nanotechnology In Medicine written by Mahendra Rai and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-19 with Science categories.
NANOTECHNOLOGY IN MEDICINE Discover thorough insights into the toxicology of nanomaterials used in medicine In Nanotechnology in Medicine: Toxicity and Safety, an expert team of nanotechnologists delivers a robust and up-to-date review of current and future applications of nanotechnology in medicine with a special focus on neurodegenerative diseases, cancer, diagnostics, nano-nutraceuticals, dermatology, and gene therapy. The editors offer resources that address nanomaterial safety, which tends to be the greatest hurdle to obtaining the benefits of nanomedicine in healthcare. The book is a one-stop resource for recent and comprehensive information on the toxico logical and safety aspects of nanotechnology used in human health and medicine. It provides readers with cutting-edge techniques for delivering therapeutic agents into targeted cellular compartments, cells, tissues, and organs by using nanoparticulate carriers. The book also offers methodological considerations for toxicity, safety, and risk assessment. Nanotechnology in Medicine: Toxicity and Safety also provides readers with: A thorough introduction to the nanotoxicological aspects of nanomedicine, including translational nanomedicine and nanomedicine personalization Comprehensive introductions to nanoparticle toxicity and safety, including selenium nanoparticles and metallic nanoparticles Practical discussions of nanotoxicology and drug delivery, including gene delivery using nanocarriers and the use of nanomaterials for ocular delivery applications In-depth examinations of nanotechnology ethics and the regulatory framework of nanotechnology and medicine Perfect for researchers, post-doctoral candidates, and specialists in the fields of nanotechnology, nanomaterials, and nanocarriers, Nanotechnology in Medicine: Toxicity and Safety will also prove to be an indispensable part of the libraries of nanoengineering, nanomedicine, and biopharmaceutical professionals and nanobiotechnologists.
Nanomaterial Biointeractions At The Cellular Organismal And System Levels
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Author : Nilesh Sharma
language : en
Publisher: Springer Nature
Release Date : 2021-03-26
Nanomaterial Biointeractions At The Cellular Organismal And System Levels written by Nilesh Sharma and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-26 with Science categories.
The range of nanomaterial applications has expanded recently from catalysis, electronics, and filtration to therapeutics, diagnostics, agriculture, and food because of unique properties and potentials of different nanoparticles and nanomaterials. Research shows that these exquisite particles can interact with an organism at the cellular, physiological, biochemical, and molecular levels. However, our knowledge of how they affect these changes, selectively or generally, in diverse organism or ecosystems is very limited and far from satisfactory. Data indicate that the biological function largely depends on the shape, size, and surface characteristics of the nanoparticles used besides life cycle stages of an organism. Therefore, this compilation will focus on the body of work carried out by distinguished investigators using diverse nanomaterials and plant and animal species. This book includes specific case studies as well as general review articles highlighting aspects of multilayered interactions, and targets not only research and academic scholars but also the concerned industry and policy makers as well.
Computational Nanotoxicology
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Author : Agnieszka Gajewicz
language : en
Publisher: CRC Press
Release Date : 2019-11-13
Computational Nanotoxicology written by Agnieszka Gajewicz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-13 with Medical categories.
The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials (ENMs) has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of ENMs, computational methods originally developed for regular chemicals cannot always be applied explicitly in nanotoxicology. This book discusses the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. It focuses on (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics), (ii) nanochemoinformatic methods (quantitative structure–activity relationship modeling, grouping, read-across), and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics). It reviews methods of calculating molecular descriptors sufficient to characterize the structure of nanoparticles, specifies recent trends in the validation of computational methods, and discusses ways to cope with the uncertainty of predictions. In addition, it highlights the status quo and further challenges in the application of computational methods in regulation (e.g., REACH, OECD) and in industry for product development and optimization and the future directions for increasing acceptance of computational modeling for nanotoxicology.
Towards Efficient Designing Of Safe Nanomaterials
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Author : Jerzy Leszczynski
language : en
Publisher: Royal Society of Chemistry
Release Date : 2012-09-30
Towards Efficient Designing Of Safe Nanomaterials written by Jerzy Leszczynski and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-30 with Science categories.
The expanding field of nanotechnology is now one of the most promising areas of science. However, because some nanoparticles can have a negative impact on human health and the environment, the design of novel materials must always be accompanied by a comprehensive risk assessment. Until now, the information on the methods available has been fragmented and incomplete. This book is the first to provide a comprehensive review of recent progress and challenges in the risk assessment of nanomaterials by empirical and computational techniques. Topics covered include: benefits versus risks, carbon based nanomaterials, environmental detection and quantitative analysis, chemometric modelling, human exposure assessment, toxicity testing, nano-QSAR, risk assessment strategies, policy and regulatory frameworks.
Nanotoxicology
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Author : Nancy A. Monteiro-Riviere
language : en
Publisher: CRC Press
Release Date : 2014-03-03
Nanotoxicology written by Nancy A. Monteiro-Riviere and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-03 with Medical categories.
Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This in
Nanotoxicology
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Author : Vineet Kumar
language : en
Publisher: CRC Press
Release Date : 2018-03-12
Nanotoxicology written by Vineet Kumar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-12 with Medical categories.
As the application of nanotechnology in the myriad disciplines of science and engineering--from agriculture, pharmaceuticals, material science, and biotechnology to sensors, electronics, and mechanical and electrical engineering--brings benefits it also can produce serious threats to human health and the environment that must be evaluated. The unique properties of nanomaterials make them different from their bulk counterparts. In addition to such unique properties, the nanometric size of nanomaterials can invite some detrimental effects on the health and well-being of living organisms and the environment. Thus, it is important to distinguish nanomaterials with such ill effects from nanomaterials with no or minimum toxicity. Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management covers issues such as the basic principles of nanotoxicity, methods used for nanotoxicity evaluation, risk assessment and its management for nanomaterial toxicity with a focus on current trends, limitations, challenges, and future directions of nanotoxicity evaluation. Various experts from different countries discuss these issues in detail in this book. This will be helpful to researchers, educators, and students who are interested in research opportunities for avoiding the environmental and health hazards of nanomaterials. This book will also be useful for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, drugs, and other regulatory sciences.
Silver Nanoparticles
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Author : Khan Maaz
language : en
Publisher: Intechopen
Release Date : 2018
Silver Nanoparticles written by Khan Maaz and has been published by Intechopen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Technology & Engineering categories.
Silver nanoparticles are the subject of immense interest because of their distinct chemical and physical properties that are different from their bulk counterpart. This makes these nanoparticles very important in many fields including antimicrobial applications, biosensor materials, composite fibers, cryogenic superconducting materials, cosmetic products, and electronic components. This book aims to provide in-depth study and analysis of various fabrication, characterization, and application techniques of silver nanoparticles that lead these nanoparticles very important in the recent technology. This book presents deep understanding of the new techniques from basic to the advanced level. This book addresses scientists, engineers, doctoral and postdoctoral fellows, and technical professionals working in specialized fields.