Modelling The Toxicity Of Nanoparticles

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Modelling The Toxicity Of Nanoparticles
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Author : Lang Tran
language : en
Publisher: Springer
Release Date : 2017-02-06
Modelling The Toxicity Of Nanoparticles written by Lang Tran and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-06 with Medical categories.
In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.
Model Organisms To Study Biological Activities And Toxicity Of Nanoparticles
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Author : Busi Siddhardha
language : en
Publisher: Springer Nature
Release Date : 2020-03-28
Model Organisms To Study Biological Activities And Toxicity Of Nanoparticles written by Busi Siddhardha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-28 with Medical categories.
This book provides a comprehensive overview of state-of-the-art applications of nanotechnology in biology and medicine, as well as model organisms that can help us understand the biological activity and associated toxicity of nanoparticles, and devise strategies to minimize toxicity and enhance therapies. Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics. The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research.
Toxicity Of Nanoparticles
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Author : Mohammed Muzibur Rahman
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-01-10
Toxicity Of Nanoparticles written by Mohammed Muzibur Rahman and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-10 with Technology & Engineering categories.
Toxicity of Nanoparticles - Recent Advances and New Perspectives covers all the important nanotechnological aspects of various metallic nanoparticles, including their growth and characterization, facile synthesis and fabrication, development, and potential applications for industrial, environmental, and healthcare purposes. Recent developments, innovative synthesis methods, metal oxides, drug delivery, bioengineering, microbiology, seafood and aquacultures, phytometallics, nanotoxicological assessment, immunotoxicity, and promising new frontiers around these advanced nanoscale materials are reviewed under the editorship of an internationally renowned scientist. This book is useful for a diverse range of readers and important for research organizations, government research centers, academic libraries, and those involved in the research and development of carbon materials.
Biochemical Toxicology
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Author : Muharrem Ince
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-07-29
Biochemical Toxicology written by Muharrem Ince and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-29 with Medical categories.
Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health.
Cellular And Molecular Toxicology Of Nanoparticles
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Author : Quaiser Saquib
language : en
Publisher: Springer
Release Date : 2018-02-16
Cellular And Molecular Toxicology Of Nanoparticles written by Quaiser Saquib and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-16 with Science categories.
This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types. Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”. The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.
Applications Of Nanotechnology In Drug Discovery And Delivery
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Author : Chukwuebuka Egbuna
language : en
Publisher: Elsevier
Release Date : 2022-08-17
Applications Of Nanotechnology In Drug Discovery And Delivery written by Chukwuebuka Egbuna and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-17 with Science categories.
Applications of Nanotechnology in Drug Discovery and Delivery, in the Drug Discovery Update series, presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials. This book brings together a global team of experts, making it an essential resource for researchers, drug developers, medicinal chemists, toxicologists and analytical chemists. - Serves as a guide to drug developers working in pharma, biotech and academia, bringing together the latest research on the topic - Presents recent information on the use of nanomaterials for the development of drugs using engineered nanocarriers to target specific delivery - Features a global team of contributing experts who discuss nanotechnology applications in drug discovery as well as safety issues and challenges
Predictive Analytics For Toxicology
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Author : Luis G. Valerio, Jr.
language : en
Publisher: CRC Press
Release Date : 2024-08-13
Predictive Analytics For Toxicology written by Luis G. Valerio, Jr. and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-13 with Science categories.
Predictive data science is already in use in many fields, but its application in toxicology is new and sought after by non-animal alternative testing initiatives. Predictive Analytics for Toxicology: Applications in Discovery Science provides a comprehensive overview of the application of predictive analytics in the field of toxicology, highlighting its role and applications in discovery science. This book addresses the challenges of accurately predicting high-level endpoints of toxicity and explores the use of computational and artificial intelligence research to automate predictive toxicology. It underscores the importance of predictive toxicology in proposing and explaining adverse outcomes resulting from human exposures to specific toxicants, especially when experimental and observational data on the toxicant are incomplete or unavailable. Key features: Includes a plain language description of predictive analytics in toxicology adding an overview of the wide range of applications Examines the science of prediction, computational models as an automated science and comprehensive discussions on concepts of machine learning Opens the hood on AI and its applications in toxicology Features coverage on how in silico toxicity predictions are translational science tools The book integrates strategies and practices of predictive toxicology and offers practical information that students and professionals of the toxicology, chemical, and pharmaceutical industries will find essential. It fulfills the expectations of student researchers seeking to learn predictive analytics in toxicology. This book will energize scientists to conduct predictive toxicology modeling using artificial intelligence and machine learning, and inspire students and seasoned scientists interested in automated science to pick up new research using predictive in silico models to evaluate chemical-induced toxicity. With its focus on practical applications and real-world examples, this book serves as a guide for navigating the complex issues and practices of discovery toxicology. It is an essential resource for those interested in computer-based methods in toxicology, providing valuable insights into the use of predictive analytics.
Advances In Nanotechnology Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Advances In Nanotechnology Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Technology & Engineering categories.
Advances in Nanotechnology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nanotechnology. The editors have built Advances in Nanotechnology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Nanotechnology Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Toxicology For The Health And Pharmaceutical Sciences
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Author : Antonio Peña-Fernández
language : en
Publisher: CRC Press
Release Date : 2021-12-21
Toxicology For The Health And Pharmaceutical Sciences written by Antonio Peña-Fernández and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-21 with Medical categories.
There is an increasing need for knowledge of toxicology to safeguard the use of chemicals in industry and in the public and private sectors. The study of toxicology is becoming increasingly relevant in human health sciences, as future health and clinical professionals will be pivotal in addressing and managing emerging chemical threats and hazards related to modern anthropogenic activities and technological development. Comprising a series of chapters from leading toxicology, pharmacy and public health academics and experts across Europe, the United States and beyond, Toxicology for the Health and Pharmaceutical Sciences provides a concise yet comprehensive volume that can be used as a relevant textbook on toxicology for the clinical, healthcare, educational and professional sectors. Key Features: Includes cutting edge information regarding the very lastest environmental threats to public health Provides a detailed case study based on a real-world scenario that allows the reader to practice human health risk assessment Describes innovative guidance and tools to respond to chemical incidents and attacks, which enables the reader to tailor an effective protection and remediation response This book covers the fundamentals and recent developments in toxicology, to respond to local and global chemical, pharmaceutical and environmental threats. Thus, this volume has chapters specifically designed to support the understanding of the most current toxicology-related subjects for any undergraduate/postgraduate health programs as well as aid the delivery of continuing professional development training on up-to-date topics in toxicology for current practicing health professionals wishing to improve their background knowledge in toxicology. The book is also vital reading and reference for policy makers and others that influence and set regulations that have an impact on the environment and human health.
Nanotechnology In Food Packaging
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Author : Awanish Kumar
language : en
Publisher: Springer Nature
Release Date : 2025-03-14
Nanotechnology In Food Packaging written by Awanish Kumar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-14 with Technology & Engineering categories.
For researchers and food industry professionals seeking a comprehensive, fully up to date single source on nanotechnology in food packaging, this text provides all the needed information. The book begins with a chapter on the current state of nanotechnology and its use in food packaging and the industry as a whole, including current advances in methods and technology. Further chapters address organic nano packaging for shelf life and quality retention, the use of inorganic nanomaterials, biopolymeric nano packaging and composite nano packaging materials. Nanotechnology in Food Packaging focuses on the methods of synthesis for nano-based food packaging materials and the fabrication of improved, active and smart packaging materials. Ethical issues and safety features of nanomaterials are addressed, plus the main challenges and regulatory aspects of nanomaterials in food products. An important chapter looks to the future of nanotechnology in the food packaging industry. Toxicological aspects, detection methods and analysis of nanomaterials are also covered in full. With its wide scope and up to date information on technological advancements, this is the perfect source for those seeking knowledge on the use of nanotechnology in the food industry.